Ligand: 844

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4BGGA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 4BGGA Q04771 203 498 509.0 844:1000 Type1 Inactive DFGin 7.6956 13.0117 BLAminus -123.75, 169.71 65.78, 89.27 -103.09, 23.33 302.35, 172.22 -60.21, -27.36 in-out in 8.6134 Saltbr-out 4.4587 HRD-in -75.04, -56.75 78.1, 3.09 out-in-out SNCoio in-out ActLoopNT-in 2.887 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -138.85, 172.45 APE9-dihe-na -51.51, 168.48 APE8-dihe-in -70.31, 126.41 APE8-rot-in 297.38 APE67-dihe-in -52.09, -31.08 -64.93, -41.24 APE12-dist-in 10.7099 APE11-dist-out 6.4804 APE10-dist-out 8.6758 APE9-dist-in 3.9644 Q207D None None XRAY 2.56 0.217 0.247 A 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 4bgg TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGB Q04771 203 498 509.0 844:1000 Type1 Inactive DFGin 7.651 13.0755 BLAminus -126.75, 170.2 64.89, 86.81 -96.93, 22.53 303.15, 172.06 -60.35, -29.64 in-out in 8.6644 Saltbr-out 4.4864 HRD-in -75.94, -57.13 76.77, 3.62 out-in-out SNCoio in-out ActLoopNT-in 2.897 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -139.3, 171.72 APE9-dihe-na -49.5, 168.53 APE8-dihe-in -70.36, 127.01 APE8-rot-in 296.26 APE67-dihe-in -54.49, -30.61 -64.06, -40.52 APE12-dist-in 10.752 APE11-dist-out 6.5389 APE10-dist-out 8.7054 APE9-dist-in 4.0183 Q207D None None XRAY 2.56 0.217 0.247 B 301.0 293.0 3 32 32 0 [[207, 497]] 1.0 4bgg TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGC Q04771 204 497 509.0 844:1000 Type1 Inactive DFGin 7.671 13.1385 BLAminus -121.52, 168.42 68.97, 89.32 -103.54, 23.49 302.06, 172.56 -58.81, -29.29 in-out in 8.7128 Saltbr-out 4.6611 HRD-in -76.71, -57.01 78.56, 1.53 out-in-out SNCoio in-out ActLoopNT-in 2.9038 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -138.8, 173.51 APE9-dihe-na -53.86, 169.02 APE8-dihe-in -71.72, 126.65 APE8-rot-in 296.78 APE67-dihe-in -51.28, -31.99 -62.56, -42.69 APE12-dist-in 10.6435 APE11-dist-out 6.63 APE10-dist-out 8.7062 APE9-dist-in 3.9695 Q207D None None XRAY 2.56 0.217 0.247 C 301.0 279.0 15 32 29 3 [[207, 497]] 1.0 4bgg TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGD Q04771 204 498 509.0 844:1000 Type1 Inactive DFGin 7.6795 13.2991 BLAminus -123.24, 170.49 65.5, 87.93 -101.92, 23.69 301.28, 172.56 -57.6, -28.63 in-out in 8.8928 Saltbr-out 4.8159 HRD-in -73.26, -58.16 80.03, 2.33 out-in-out SNCoio in-out ActLoopNT-in 2.8812 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -139.49, 172.0 APE9-dihe-na -51.1, 169.58 APE8-dihe-in -71.78, 124.32 APE8-rot-in 297.27 APE67-dihe-in -52.31, -32.65 -62.65, -40.28 APE12-dist-in 10.7442 APE11-dist-out 6.7574 APE10-dist-out 8.6752 APE9-dist-in 3.9622 Q207D None None XRAY 2.56 0.217 0.247 D 301.0 286.0 9 32 32 0 [[207, 497]] 1.0 4bgg TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: 844

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4BGGA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 4BGGA Q04771 203 498 509.0 844:1000 Type1 Inactive DFGin 7.6956 13.0117 BLAminus -123.75, 169.71 65.78, 89.27 -103.09, 23.33 302.35, 172.22 -60.21, -27.36 in-out in 8.6134 Saltbr-out 4.4587 HRD-in -75.04, -56.75 78.1, 3.09 out-in-out SNCoio in-out ActLoopNT-in 2.887 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -138.85, 172.45 APE9-dihe-na -51.51, 168.48 APE8-dihe-in -70.31, 126.41 APE8-rot-in 297.38 APE67-dihe-in -52.09, -31.08 -64.93, -41.24 APE12-dist-in 10.7099 APE11-dist-out 6.4804 APE10-dist-out 8.6758 APE9-dist-in 3.9644 Q207D None None XRAY 2.56 0.217 0.247 A 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 4bgg Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGB Q04771 203 498 509.0 844:1000 Type1 Inactive DFGin 7.651 13.0755 BLAminus -126.75, 170.2 64.89, 86.81 -96.93, 22.53 303.15, 172.06 -60.35, -29.64 in-out in 8.6644 Saltbr-out 4.4864 HRD-in -75.94, -57.13 76.77, 3.62 out-in-out SNCoio in-out ActLoopNT-in 2.897 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -139.3, 171.72 APE9-dihe-na -49.5, 168.53 APE8-dihe-in -70.36, 127.01 APE8-rot-in 296.26 APE67-dihe-in -54.49, -30.61 -64.06, -40.52 APE12-dist-in 10.752 APE11-dist-out 6.5389 APE10-dist-out 8.7054 APE9-dist-in 4.0183 Q207D None None XRAY 2.56 0.217 0.247 B 301.0 293.0 3 32 32 0 [[207, 497]] 1.0 4bgg Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGC Q04771 204 497 509.0 844:1000 Type1 Inactive DFGin 7.671 13.1385 BLAminus -121.52, 168.42 68.97, 89.32 -103.54, 23.49 302.06, 172.56 -58.81, -29.29 in-out in 8.7128 Saltbr-out 4.6611 HRD-in -76.71, -57.01 78.56, 1.53 out-in-out SNCoio in-out ActLoopNT-in 2.9038 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -138.8, 173.51 APE9-dihe-na -53.86, 169.02 APE8-dihe-in -71.72, 126.65 APE8-rot-in 296.78 APE67-dihe-in -51.28, -31.99 -62.56, -42.69 APE12-dist-in 10.6435 APE11-dist-out 6.63 APE10-dist-out 8.7062 APE9-dist-in 3.9695 Q207D None None XRAY 2.56 0.217 0.247 C 301.0 279.0 15 32 29 3 [[207, 497]] 1.0 4bgg Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGD Q04771 204 498 509.0 844:1000 Type1 Inactive DFGin 7.6795 13.2991 BLAminus -123.24, 170.49 65.5, 87.93 -101.92, 23.69 301.28, 172.56 -57.6, -28.63 in-out in 8.8928 Saltbr-out 4.8159 HRD-in -73.26, -58.16 80.03, 2.33 out-in-out SNCoio in-out ActLoopNT-in 2.8812 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -139.49, 172.0 APE9-dihe-na -51.1, 169.58 APE8-dihe-in -71.78, 124.32 APE8-rot-in 297.27 APE67-dihe-in -52.31, -32.65 -62.65, -40.28 APE12-dist-in 10.7442 APE11-dist-out 6.7574 APE10-dist-out 8.6752 APE9-dist-in 3.9622 Q207D None None XRAY 2.56 0.217 0.247 D 301.0 286.0 9 32 32 0 [[207, 497]] 1.0 4bgg Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: 844

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name