Ligand: 7QU

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7RUNB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR RET RET_HUMAN 7RUNA P07949 705 1012 1114.0 7QU:1102 Type1.5_Back Inactive DFGin 6.6277 14.2475 BLAminus -134.77, -173.78 63.39, 56.13 -81.71, 19.24 291.69, 108.11 -66.54, -40.45 in-in in 7.5877 Saltbr-in 3.4576 HRD-in -98.1, -27.51 77.75, -68.34 in-in-out SNCiio in-out ActLoopNT-in 2.6867 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -96.35, -14.09 APE9-dihe-in -83.31, 135.75 APE8-dihe-in -58.85, 127.12 APE8-rot-na 17.23 APE67-dihe-in -70.31, -31.91 -52.84, -32.19 APE12-dist-na 11.7648 APE11-dist-na 10.7144 APE10-dist-na 6.9339 APE9-dist-in 6.2386 None PTR809,PTR905,SEP909,PTR928 PTR809,PTR905,SEP909,PTR928 XRAY 3.51 0.222 0.247 A 334.0 287.0 21 30 30 0 [[724, 1007]] 1.0 7run TYR_RET_HUMAN TYR 5.1e-101 343.3 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7RUNB P07949 706 1012 1114.0 7QU:1102 Type1.5_Back Inactive DFGin 6.4786 14.1723 BLAminus -134.95, -173.5 63.71, 56.59 -81.67, 19.29 291.63, 107.9 -66.46, -40.71 in-in in 7.592 Saltbr-in 3.3853 HRD-in -99.07, -30.7 75.06, -75.74 in-in-out SNCiio in-out ActLoopNT-in 2.7037 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -94.95, -13.05 APE9-dihe-in -82.84, 135.71 APE8-dihe-in -58.94, 126.93 APE8-rot-na 17.11 APE67-dihe-in -69.79, -32.06 -52.79, -32.62 APE12-dist-na 11.8666 APE11-dist-na 10.6868 APE10-dist-na 6.8204 APE9-dist-in 6.5907 None PTR809,PTR905,SEP909,PTR928 PTR809,PTR905,SEP909,PTR928 XRAY 3.51 0.222 0.247 B 334.0 288.0 19 30 30 0 [[724, 1007]] 1.0 7run TYR_RET_HUMAN TYR 5.1e-101 343.3 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: 7QU

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7RUNB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR RET RET_HUMAN 7RUNA P07949 705 1012 1114.0 7QU:1102 Type1.5_Back Inactive DFGin 6.6277 14.2475 BLAminus -134.77, -173.78 63.39, 56.13 -81.71, 19.24 291.69, 108.11 -66.54, -40.45 in-in in 7.5877 Saltbr-in 3.4576 HRD-in -98.1, -27.51 77.75, -68.34 in-in-out SNCiio in-out ActLoopNT-in 2.6867 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -96.35, -14.09 APE9-dihe-in -83.31, 135.75 APE8-dihe-in -58.85, 127.12 APE8-rot-na 17.23 APE67-dihe-in -70.31, -31.91 -52.84, -32.19 APE12-dist-na 11.7648 APE11-dist-na 10.7144 APE10-dist-na 6.9339 APE9-dist-in 6.2386 None PTR809,PTR905,SEP909,PTR928 PTR809,PTR905,SEP909,PTR928 XRAY 3.51 0.222 0.247 A 334.0 287.0 21 30 30 0 [[724, 1007]] 1.0 7run Homo sapiens TYR_RET_HUMAN TYR 5.1e-101 343.3 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7RUNB P07949 706 1012 1114.0 7QU:1102 Type1.5_Back Inactive DFGin 6.4786 14.1723 BLAminus -134.95, -173.5 63.71, 56.59 -81.67, 19.29 291.63, 107.9 -66.46, -40.71 in-in in 7.592 Saltbr-in 3.3853 HRD-in -99.07, -30.7 75.06, -75.74 in-in-out SNCiio in-out ActLoopNT-in 2.7037 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -94.95, -13.05 APE9-dihe-in -82.84, 135.71 APE8-dihe-in -58.94, 126.93 APE8-rot-na 17.11 APE67-dihe-in -69.79, -32.06 -52.79, -32.62 APE12-dist-na 11.8666 APE11-dist-na 10.6868 APE10-dist-na 6.8204 APE9-dist-in 6.5907 None PTR809,PTR905,SEP909,PTR928 PTR809,PTR905,SEP909,PTR928 XRAY 3.51 0.222 0.247 B 334.0 288.0 19 30 30 0 [[724, 1007]] 1.0 7run Homo sapiens TYR_RET_HUMAN TYR 5.1e-101 343.3 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: 7QU

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name