Ligand: 7GB

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 100.0% 5P9MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 5P9MA Q06187 389 659 659.0 7GB:701 Type1.5_Back Inactive DFGin 5.8516 13.3293 BLBplus -132.36, 168.19 59.41, 28.36 -65.38, 123.69 35.52, 89.9 75.34, -4.93 out-out out 14.7801 Saltbr-out 15.0393 HRD-in -68.48, -50.59 79.48, -16.76 out-out-out SNCooo out-out ActLoopNT-out 8.1708 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -51.99, -28.41 APE9-dihe-in -155.94, 144.77 APE8-dihe-in -76.22, 66.03 APE8-rot-na 26.43 APE67-dihe-in -70.51, -11.44 -52.67, -42.73 APE12-dist-na 16.2836 APE11-dist-na 16.7244 APE10-dist-na 16.1093 APE9-dist-out 8.8831 None None None XRAY 1.41 0.18 0.201 A 279.0 271.0 0 29 29 0 [[402, 653]] 1.0 5p9m TYR_BTK_HUMAN TYR 6.7e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 7GB

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 5P9MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 5P9MA Q06187 389 659 659.0 7GB:701 Type1.5_Back Inactive DFGin 5.8516 13.3293 BLBplus -132.36, 168.19 59.41, 28.36 -65.38, 123.69 35.52, 89.9 75.34, -4.93 out-out out 14.7801 Saltbr-out 15.0393 HRD-in -68.48, -50.59 79.48, -16.76 out-out-out SNCooo out-out ActLoopNT-out 8.1708 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -51.99, -28.41 APE9-dihe-in -155.94, 144.77 APE8-dihe-in -76.22, 66.03 APE8-rot-na 26.43 APE67-dihe-in -70.51, -11.44 -52.67, -42.73 APE12-dist-na 16.2836 APE11-dist-na 16.7244 APE10-dist-na 16.1093 APE9-dist-out 8.8831 None None None XRAY 1.41 0.18 0.201 A 279.0 271.0 0 29 29 0 [[402, 653]] 1.0 5p9m Homo sapiens TYR_BTK_HUMAN TYR 6.7e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_MOUSE 8FF0A P35991 396 659 659.0 7GB:60801 Type1.5_Back Inactive DFGin 5.2191 13.6773 BLBplus -132.25, 167.19 58.69, 27.63 -65.72, 123.75 35.91, 87.62 75.14, 19.75 out-none out 14.9533 Saltbr-none 999.0 HRD-in -69.37, -50.08 80.05, -16.38 none-out-out SNCnoo out-out ActLoopNT-out 7.7789 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -100.85, -26.74 APE9-dihe-in -55.22, 143.13 APE8-dihe-in -77.98, 65.87 APE8-rot-na 26.46 APE67-dihe-in -65.77, -20.77 -52.66, -49.09 APE12-dist-na 17.1354 APE11-dist-na 19.1037 APE10-dist-na 13.5458 APE9-dist-out 8.8625 K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P None None XRAY 2.6 0.242 0.267 A 271.0 264.0 0 29 29 0 [[402, 653]] 1.0 8ff0 Mus musculus TYR_BTK_MOUSE TYR 1.1e-92 316.0 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 7GB

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 100.0% 8FF0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_MOUSE 8FF0A P35991 396 659 659.0 7GB:60801 Type1.5_Back Inactive DFGin 5.2191 13.6773 BLBplus -132.25, 167.19 58.69, 27.63 -65.72, 123.75 35.91, 87.62 75.14, 19.75 out-none out 14.9533 Saltbr-none 999.0 HRD-in -69.37, -50.08 80.05, -16.38 none-out-out SNCnoo out-out ActLoopNT-out 7.7789 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -100.85, -26.74 APE9-dihe-in -55.22, 143.13 APE8-dihe-in -77.98, 65.87 APE8-rot-na 26.46 APE67-dihe-in -65.77, -20.77 -52.66, -49.09 APE12-dist-na 17.1354 APE11-dist-na 19.1037 APE10-dist-na 13.5458 APE9-dist-out 8.8625 K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P None None XRAY 2.6 0.242 0.267 A 271.0 264.0 0 29 29 0 [[402, 653]] 1.0 8ff0 Mus musculus TYR_BTK_MOUSE TYR 1.1e-92 316.0 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK