Ligand: 734

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4E26A
DFGin BLBminus 1 50.0% 4E26B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 4E26A P15056 448 723 766.0 734:801 Type1 Inactive DFGin 6.5482 14.2593 BLAminus -123.09, -155.83 45.29, 82.31 -99.48, 28.47 287.12, 71.36 -65.78, -23.11 in-in in 8.4735 Saltbr-in 3.2762 HRD-in -66.92, -52.0 73.01, 1.38 in-in-out SNCiio in-out ActLoopNT-in 2.8821 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na 176.82, 70.9 APE9-dihe-na -151.07, -48.08 APE8-dihe-in -102.0, 76.55 APE8-rot-out 48.66 APE67-dihe-in -58.71, -28.19 -81.89, -17.55 APE12-dist-out 6.5262 APE11-dist-out 6.9536 APE10-dist-out 12.2841 APE9-dist-out 10.1918 None None None XRAY 2.55 0.22 0.262 A 307.0 270.0 6 30 24 6 [[457, 716]] 1.0 4e26 TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E26B P15056 448 722 766.0 734:801 Type1 Inactive DFGin 6.3612 14.2602 BLBminus -129.24, -167.87 46.52, 96.15 -111.58, -138.63 293.59, 65.8 80.77, -62.67 in-in in 8.0431 Saltbr-in 3.0381 HRD-in -58.73, -54.71 74.73, 10.01 in-in-out SNCiio in-out ActLoopNT-in 2.8443 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, -177.61 APE9-dihe-na -153.13, 152.76 APE8-dihe-out -144.56, 37.84 APE8-rot-in 294.76 APE67-dihe-in -56.79, -31.94 -61.82, -28.63 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.7224 APE9-dist-out 10.4345 None None None XRAY 2.55 0.22 0.262 B 307.0 264.0 11 30 19 11 [[457, 716]] 1.0 4e26 TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

Ligand: 734

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4E26A
DFGin BLBminus 1 50.0% 4E26B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 4E26A P15056 448 723 766.0 734:801 Type1 Inactive DFGin 6.5482 14.2593 BLAminus -123.09, -155.83 45.29, 82.31 -99.48, 28.47 287.12, 71.36 -65.78, -23.11 in-in in 8.4735 Saltbr-in 3.2762 HRD-in -66.92, -52.0 73.01, 1.38 in-in-out SNCiio in-out ActLoopNT-in 2.8821 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na 176.82, 70.9 APE9-dihe-na -151.07, -48.08 APE8-dihe-in -102.0, 76.55 APE8-rot-out 48.66 APE67-dihe-in -58.71, -28.19 -81.89, -17.55 APE12-dist-out 6.5262 APE11-dist-out 6.9536 APE10-dist-out 12.2841 APE9-dist-out 10.1918 None None None XRAY 2.55 0.22 0.262 A 307.0 270.0 6 30 24 6 [[457, 716]] 1.0 4e26 Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E26B P15056 448 722 766.0 734:801 Type1 Inactive DFGin 6.3612 14.2602 BLBminus -129.24, -167.87 46.52, 96.15 -111.58, -138.63 293.59, 65.8 80.77, -62.67 in-in in 8.0431 Saltbr-in 3.0381 HRD-in -58.73, -54.71 74.73, 10.01 in-in-out SNCiio in-out ActLoopNT-in 2.8443 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, -177.61 APE9-dihe-na -153.13, 152.76 APE8-dihe-out -144.56, 37.84 APE8-rot-in 294.76 APE67-dihe-in -56.79, -31.94 -61.82, -28.63 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.7224 APE9-dist-out 10.4345 None None None XRAY 2.55 0.22 0.262 B 307.0 264.0 11 30 19 11 [[457, 716]] 1.0 4e26 Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

Ligand: 734

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name