Ligand: 6TP

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3TJDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3TJDA O60674 843 1132 1132.0 6TP:1 Type1 Inactive DFGin 5.9907 13.6677 ABAminus -106.4, 6.86 -148.97, 135.33 -126.71, 31.52 298.26, 96.91 -65.03, -17.37 in-in in 8.6613 Saltbr-in 2.4046 HRD-in -60.32, -42.09 57.24, 2.17 in-in-in SNCiii in-in ActLoopNT-in 2.7555 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.99, 136.33 APE9-dihe-in -114.67, 153.5 APE8-dihe-in -80.71, 62.46 APE8-rot-na 37.92 APE67-dihe-in -72.13, 9.26 -46.3, -36.88 APE12-dist-na 12.8734 APE11-dist-na 12.7661 APE10-dist-na 12.946 APE9-dist-in 7.8339 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.9 0.286 0.312 A 298.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjd TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJDB O60674 840 1132 1132.0 6TP:1 Type1 Inactive DFGin 6.3888 13.998 ABAminus -115.4, 19.45 -153.78, 133.17 -126.99, 29.7 296.86, 92.39 -60.7, -23.46 in-in in 8.4717 Saltbr-in 2.8991 HRD-in -70.92, -38.15 64.72, -21.56 in-in-in SNCiii in-in ActLoopNT-in 2.8078 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -58.27, 138.19 APE9-dihe-in -112.71, 149.09 APE8-dihe-in -82.04, 69.58 APE8-rot-na 37.61 APE67-dihe-in -79.66, -3.25 -52.11, -26.43 APE12-dist-na 12.3993 APE11-dist-na 10.6915 APE10-dist-na 12.3131 APE9-dist-in 7.8262 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.9 0.286 0.312 B 298.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjd TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: 6TP

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3TJDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3TJDA O60674 843 1132 1132.0 6TP:1 Type1 Inactive DFGin 5.9907 13.6677 ABAminus -106.4, 6.86 -148.97, 135.33 -126.71, 31.52 298.26, 96.91 -65.03, -17.37 in-in in 8.6613 Saltbr-in 2.4046 HRD-in -60.32, -42.09 57.24, 2.17 in-in-in SNCiii in-in ActLoopNT-in 2.7555 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.99, 136.33 APE9-dihe-in -114.67, 153.5 APE8-dihe-in -80.71, 62.46 APE8-rot-na 37.92 APE67-dihe-in -72.13, 9.26 -46.3, -36.88 APE12-dist-na 12.8734 APE11-dist-na 12.7661 APE10-dist-na 12.946 APE9-dist-in 7.8339 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.9 0.286 0.312 A 298.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjd Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJDB O60674 840 1132 1132.0 6TP:1 Type1 Inactive DFGin 6.3888 13.998 ABAminus -115.4, 19.45 -153.78, 133.17 -126.99, 29.7 296.86, 92.39 -60.7, -23.46 in-in in 8.4717 Saltbr-in 2.8991 HRD-in -70.92, -38.15 64.72, -21.56 in-in-in SNCiii in-in ActLoopNT-in 2.8078 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -58.27, 138.19 APE9-dihe-in -112.71, 149.09 APE8-dihe-in -82.04, 69.58 APE8-rot-na 37.61 APE67-dihe-in -79.66, -3.25 -52.11, -26.43 APE12-dist-na 12.3993 APE11-dist-na 10.6915 APE10-dist-na 12.3131 APE9-dist-in 7.8262 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.9 0.286 0.312 B 298.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjd Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: 6TP

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name