Ligand: 6A7

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5IDNA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK8 CDK8_HUMAN 5IDNA 2.26 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 6A7 Type1 1 - 363 0 None None Cyclin-dependent kinase 8

Ligand: 6A7

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5IDNA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK8 CDK8_HUMAN 5IDNA 2.26 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 6A7 Type1 1 - 363 0 None None Cyclin-dependent kinase 8 Homo sapiens

Ligand: 6A7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism