Ligand: 65L

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 7VDPA
DFGin BLBtrans 1 33.3% 7VDUA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 7VDUA 1.53 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaioi APEdist_oooo 65L Type1 1 - 296 0 None None Cyclin-dependent kinase 2
CMGC CDK5 CDK5_HUMAN 7VDPA 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 2 - 291 0 None None Cyclin-dependent kinase 5
CMGC CDK5 CDK5_HUMAN 7VDPB 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 3 - 288 0 None None Cyclin-dependent kinase 5

Ligand: 65L

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 7VDPA
DFGin BLBtrans 1 33.3% 7VDUA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 7VDUA 1.53 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaioi APEdist_oooo 65L Type1 1 - 296 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK5 CDK5_HUMAN 7VDPA 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 2 - 291 0 None None Cyclin-dependent kinase 5 Homo sapiens
CMGC CDK5 CDK5_HUMAN 7VDPB 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 3 - 288 0 None None Cyclin-dependent kinase 5 Homo sapiens

Ligand: 65L

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism