Ligand: 5YV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7P6PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC ROCK2 ROCK2_HUMAN 7P6PA O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.1436 13.4975 BLAminus -132.07, 172.67 54.56, 93.15 -112.26, 31.75 305.01, 96.0 -65.02, -28.17 in-in in 8.9359 Saltbr-in 2.7077 HRD-in -75.76, -48.68 68.71, 2.45 in-in-out SNCiio in-out ActLoopNT-in 3.0199 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_onoo APE10-dihe-na 999.0, -37.69 APE9-dihe-na 68.06, 165.75 APE8-dihe-out 49.49, 69.05 APE8-rot-out 51.42 APE67-dihe-in -43.22, -41.5 -67.31, -24.58 APE12-dist-out 5.8964 APE11-dist-none 999.0 APE10-dist-out 8.8145 APE9-dist-out 9.313 None None None XRAY 2.82 0.222 0.258 A 399.0 389.0 1 29 28 1 [[92, 354]] 1.0 7p6p AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6PB O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.1537 13.387 BLAminus -129.93, 173.86 61.04, 88.71 -108.06, 31.11 304.98, 97.36 -66.26, -28.42 in-in in 8.705 Saltbr-in 3.1205 HRD-in -76.63, -48.03 68.67, 4.31 in-in-out SNCiio in-out ActLoopNT-in 3.0234 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 131.26 APE8-rot-out 47.95 APE67-dihe-in -44.6, -41.1 -70.73, -25.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.82 0.222 0.258 B 399.0 374.0 15 29 17 12 [[92, 354]] 1.0 7p6p AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6PC O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.183 13.4382 BLAminus -129.72, 174.14 60.9, 87.88 -108.85, 31.32 304.91, 96.4 -66.49, -26.92 in-in in 8.7175 Saltbr-in 3.1215 HRD-in -77.5, -47.77 68.57, 3.01 in-in-out SNCiio in-out ActLoopNT-in 3.0284 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 132.51 APE8-rot-out 47.87 APE67-dihe-in -49.24, -39.17 -68.89, -25.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.82 0.222 0.258 C 399.0 378.0 12 29 18 11 [[92, 354]] 1.0 7p6p AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6PD O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.1385 13.3878 BLAminus -129.14, 174.38 61.55, 87.6 -108.19, 31.9 304.73, 96.8 -65.3, -27.92 in-in in 8.7545 Saltbr-in 3.1392 HRD-in -76.81, -47.84 67.84, 3.94 in-in-out SNCiio in-out ActLoopNT-in 3.0286 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.04, 138.37 APE9-dihe-na 76.18, 149.98 APE8-dihe-in -41.73, 133.73 APE8-rot-out 47.62 APE67-dihe-in -47.73, -39.5 -71.48, -25.27 APE12-dist-in 11.0305 APE11-dist-in 11.225 APE10-dist-in 6.1393 APE9-dist-in 5.154 None None None XRAY 2.82 0.222 0.258 D 399.0 383.0 6 29 27 2 [[92, 354]] 1.0 7p6p AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2

Ligand: 5YV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7P6PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC ROCK2 ROCK2_HUMAN 7P6PA O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.1436 13.4975 BLAminus -132.07, 172.67 54.56, 93.15 -112.26, 31.75 305.01, 96.0 -65.02, -28.17 in-in in 8.9359 Saltbr-in 2.7077 HRD-in -75.76, -48.68 68.71, 2.45 in-in-out SNCiio in-out ActLoopNT-in 3.0199 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_onoo APE10-dihe-na 999.0, -37.69 APE9-dihe-na 68.06, 165.75 APE8-dihe-out 49.49, 69.05 APE8-rot-out 51.42 APE67-dihe-in -43.22, -41.5 -67.31, -24.58 APE12-dist-out 5.8964 APE11-dist-none 999.0 APE10-dist-out 8.8145 APE9-dist-out 9.313 None None None XRAY 2.82 0.222 0.258 A 399.0 389.0 1 29 28 1 [[92, 354]] 1.0 7p6p Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6PB O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.1537 13.387 BLAminus -129.93, 173.86 61.04, 88.71 -108.06, 31.11 304.98, 97.36 -66.26, -28.42 in-in in 8.705 Saltbr-in 3.1205 HRD-in -76.63, -48.03 68.67, 4.31 in-in-out SNCiio in-out ActLoopNT-in 3.0234 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 131.26 APE8-rot-out 47.95 APE67-dihe-in -44.6, -41.1 -70.73, -25.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.82 0.222 0.258 B 399.0 374.0 15 29 17 12 [[92, 354]] 1.0 7p6p Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6PC O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.183 13.4382 BLAminus -129.72, 174.14 60.9, 87.88 -108.85, 31.32 304.91, 96.4 -66.49, -26.92 in-in in 8.7175 Saltbr-in 3.1215 HRD-in -77.5, -47.77 68.57, 3.01 in-in-out SNCiio in-out ActLoopNT-in 3.0284 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 132.51 APE8-rot-out 47.87 APE67-dihe-in -49.24, -39.17 -68.89, -25.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.82 0.222 0.258 C 399.0 378.0 12 29 18 11 [[92, 354]] 1.0 7p6p Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6PD O75116 24 417 1388.0 5YV:501 Type1 Inactive DFGin 6.1385 13.3878 BLAminus -129.14, 174.38 61.55, 87.6 -108.19, 31.9 304.73, 96.8 -65.3, -27.92 in-in in 8.7545 Saltbr-in 3.1392 HRD-in -76.81, -47.84 67.84, 3.94 in-in-out SNCiio in-out ActLoopNT-in 3.0286 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.04, 138.37 APE9-dihe-na 76.18, 149.98 APE8-dihe-in -41.73, 133.73 APE8-rot-out 47.62 APE67-dihe-in -47.73, -39.5 -71.48, -25.27 APE12-dist-in 11.0305 APE11-dist-in 11.225 APE10-dist-in 6.1393 APE9-dist-in 5.154 None None None XRAY 2.82 0.222 0.258 D 399.0 383.0 6 29 27 2 [[92, 354]] 1.0 7p6p Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2

Ligand: 5YV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name