| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NA | O75116 | 24 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9603 | 12.8924 | BLAminus | -147.52, 173.21 | 55.09, 95.25 | -112.31, 21.69 | 306.93, 92.98 | -47.43, -30.39 | in-in | in | 8.6076 | Saltbr-in | 2.8602 | HRD-in | -68.21, -48.5 | 74.44, -76.91 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1915 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_niio | APE10-dihe-na | -137.17, 134.7 | APE9-dihe-na | 66.08, 179.98 | APE8-dihe-in | -79.2, 152.03 | APE8-rot-out | 39.36 | APE67-dihe-in | -55.24, -42.06 | -64.41, -46.65 | APE12-dist-none | 999.0 | APE11-dist-in | 9.5364 | APE10-dist-in | 6.7557 | APE9-dist-out | 7.0612 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | A | 399.0 | 384.0 | 6 | 29 | 26 | 3 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NB | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9177 | 12.9079 | BLAminus | -147.26, 173.64 | 54.74, 95.37 | -112.38, 21.14 | 305.76, 93.69 | -46.34, -30.83 | in-in | in | 8.6582 | Saltbr-in | 2.8521 | HRD-in | -68.62, -48.31 | 74.92, -77.15 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1963 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 152.85 | APE8-rot-out | 38.72 | APE67-dihe-in | -58.22, -39.82 | -64.87, -46.83 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | B | 399.0 | 385.0 | 8 | 29 | 25 | 4 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NC | O75116 | 23 | 417 | 1388.0 | 5YS:501 | Type1 | None | DFGin | 5.9336 | 12.9198 | BLAminus | -146.55, 173.64 | 55.03, 95.19 | -112.85, 21.67 | 306.28, 93.38 | -46.66, -30.29 | in-in | in | 8.6716 | Saltbr-in | 2.8448 | HRD-in | -68.54, -48.47 | 75.35, -77.76 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.1882 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -54.16, -41.45 | 999.0, -46.08 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | C | 399.0 | 378.0 | 12 | 29 | 23 | 6 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6ND | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9112 | 12.8869 | BLAminus | -147.57, 174.08 | 54.32, 95.38 | -112.83, 20.77 | 305.2, 94.02 | -46.7, -30.3 | in-in | in | 8.6465 | Saltbr-in | 2.8456 | HRD-in | -68.81, -47.96 | 75.21, -77.34 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1908 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiio | APE10-dihe-na | -138.24, 168.24 | APE9-dihe-na | 66.25, -164.28 | APE8-dihe-in | -79.15, 151.39 | APE8-rot-out | 38.92 | APE67-dihe-in | -57.2, -39.94 | -65.63, -47.15 | APE12-dist-in | 12.8721 | APE11-dist-in | 11.2239 | APE10-dist-in | 6.1189 | APE9-dist-out | 7.0124 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | D | 399.0 | 385.0 | 4 | 29 | 29 | 0 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NE | O75116 | 23 | 417 | 1388.0 | 5YS:501 | Type1 | None | DFGin | 5.9547 | 12.8666 | BLAminus | -145.98, 174.14 | 54.43, 95.4 | -112.52, 20.29 | 306.04, 93.17 | -47.1, -30.89 | in-in | in | 8.6001 | Saltbr-in | 2.8492 | HRD-in | -68.77, -48.13 | 75.51, -77.25 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.1937 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -55.16, -41.37 | 999.0, -45.23 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | E | 399.0 | 385.0 | 6 | 29 | 23 | 6 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NF | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9261 | 12.9235 | BLAminus | -146.77, 174.8 | 54.66, 94.69 | -112.86, 21.29 | 304.94, 93.72 | -46.03, -30.46 | in-in | in | 8.6588 | Saltbr-in | 2.8458 | HRD-in | -68.6, -48.35 | 74.88, -77.16 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1986 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiio | APE10-dihe-na | -139.14, 168.92 | APE9-dihe-na | 66.99, -163.85 | APE8-dihe-in | -78.8, 151.2 | APE8-rot-out | 38.36 | APE67-dihe-in | -57.1, -40.42 | -65.28, -46.28 | APE12-dist-in | 11.5866 | APE11-dist-in | 11.279 | APE10-dist-in | 6.1627 | APE9-dist-out | 7.029 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | F | 399.0 | 384.0 | 5 | 29 | 29 | 0 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NG | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9599 | 12.8721 | BLAminus | -147.02, 173.65 | 54.4, 95.21 | -112.65, 21.16 | 306.2, 93.32 | -46.85, -30.81 | in-in | in | 8.6136 | Saltbr-in | 2.8449 | HRD-in | -68.3, -48.58 | 74.65, -77.07 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1927 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 153.91 | APE8-rot-out | 38.81 | APE67-dihe-in | -55.86, -41.48 | -64.55, -46.84 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | G | 399.0 | 385.0 | 4 | 29 | 25 | 4 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NH | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | None | DFGin | 5.9239 | 12.9869 | BLAminus | -147.12, 173.74 | 54.77, 95.23 | -112.35, 21.15 | 305.58, 93.62 | -44.02, -31.78 | in-in | in | 8.7536 | Saltbr-in | 2.8397 | HRD-in | -68.48, -48.35 | 74.56, -77.19 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.1944 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -56.65, -39.86 | 999.0, -45.7 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | H | 399.0 | 366.0 | 23 | 29 | 14 | 15 | [[92, 354]] | 1.0 | 7p6n | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NA | O75116 | 24 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9603 | 12.8924 | BLAminus | -147.52, 173.21 | 55.09, 95.25 | -112.31, 21.69 | 306.93, 92.98 | -47.43, -30.39 | in-in | in | 8.6076 | Saltbr-in | 2.8602 | HRD-in | -68.21, -48.5 | 74.44, -76.91 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1915 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_niio | APE10-dihe-na | -137.17, 134.7 | APE9-dihe-na | 66.08, 179.98 | APE8-dihe-in | -79.2, 152.03 | APE8-rot-out | 39.36 | APE67-dihe-in | -55.24, -42.06 | -64.41, -46.65 | APE12-dist-none | 999.0 | APE11-dist-in | 9.5364 | APE10-dist-in | 6.7557 | APE9-dist-out | 7.0612 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | A | 399.0 | 384.0 | 6 | 29 | 26 | 3 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NB | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9177 | 12.9079 | BLAminus | -147.26, 173.64 | 54.74, 95.37 | -112.38, 21.14 | 305.76, 93.69 | -46.34, -30.83 | in-in | in | 8.6582 | Saltbr-in | 2.8521 | HRD-in | -68.62, -48.31 | 74.92, -77.15 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1963 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 152.85 | APE8-rot-out | 38.72 | APE67-dihe-in | -58.22, -39.82 | -64.87, -46.83 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | B | 399.0 | 385.0 | 8 | 29 | 25 | 4 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NC | O75116 | 23 | 417 | 1388.0 | 5YS:501 | Type1 | None | DFGin | 5.9336 | 12.9198 | BLAminus | -146.55, 173.64 | 55.03, 95.19 | -112.85, 21.67 | 306.28, 93.38 | -46.66, -30.29 | in-in | in | 8.6716 | Saltbr-in | 2.8448 | HRD-in | -68.54, -48.47 | 75.35, -77.76 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.1882 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -54.16, -41.45 | 999.0, -46.08 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | C | 399.0 | 378.0 | 12 | 29 | 23 | 6 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6ND | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9112 | 12.8869 | BLAminus | -147.57, 174.08 | 54.32, 95.38 | -112.83, 20.77 | 305.2, 94.02 | -46.7, -30.3 | in-in | in | 8.6465 | Saltbr-in | 2.8456 | HRD-in | -68.81, -47.96 | 75.21, -77.34 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1908 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiio | APE10-dihe-na | -138.24, 168.24 | APE9-dihe-na | 66.25, -164.28 | APE8-dihe-in | -79.15, 151.39 | APE8-rot-out | 38.92 | APE67-dihe-in | -57.2, -39.94 | -65.63, -47.15 | APE12-dist-in | 12.8721 | APE11-dist-in | 11.2239 | APE10-dist-in | 6.1189 | APE9-dist-out | 7.0124 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | D | 399.0 | 385.0 | 4 | 29 | 29 | 0 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NE | O75116 | 23 | 417 | 1388.0 | 5YS:501 | Type1 | None | DFGin | 5.9547 | 12.8666 | BLAminus | -145.98, 174.14 | 54.43, 95.4 | -112.52, 20.29 | 306.04, 93.17 | -47.1, -30.89 | in-in | in | 8.6001 | Saltbr-in | 2.8492 | HRD-in | -68.77, -48.13 | 75.51, -77.25 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.1937 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -55.16, -41.37 | 999.0, -45.23 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | E | 399.0 | 385.0 | 6 | 29 | 23 | 6 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NF | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9261 | 12.9235 | BLAminus | -146.77, 174.8 | 54.66, 94.69 | -112.86, 21.29 | 304.94, 93.72 | -46.03, -30.46 | in-in | in | 8.6588 | Saltbr-in | 2.8458 | HRD-in | -68.6, -48.35 | 74.88, -77.16 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1986 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiio | APE10-dihe-na | -139.14, 168.92 | APE9-dihe-na | 66.99, -163.85 | APE8-dihe-in | -78.8, 151.2 | APE8-rot-out | 38.36 | APE67-dihe-in | -57.1, -40.42 | -65.28, -46.28 | APE12-dist-in | 11.5866 | APE11-dist-in | 11.279 | APE10-dist-in | 6.1627 | APE9-dist-out | 7.029 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | F | 399.0 | 384.0 | 5 | 29 | 29 | 0 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NG | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | Inactive | DFGin | 5.9599 | 12.8721 | BLAminus | -147.02, 173.65 | 54.4, 95.21 | -112.65, 21.16 | 306.2, 93.32 | -46.85, -30.81 | in-in | in | 8.6136 | Saltbr-in | 2.8449 | HRD-in | -68.3, -48.58 | 74.65, -77.07 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1927 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 153.91 | APE8-rot-out | 38.81 | APE67-dihe-in | -55.86, -41.48 | -64.55, -46.84 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | G | 399.0 | 385.0 | 4 | 29 | 25 | 4 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6NH | O75116 | 25 | 417 | 1388.0 | 5YS:501 | Type1 | None | DFGin | 5.9239 | 12.9869 | BLAminus | -147.12, 173.74 | 54.77, 95.23 | -112.35, 21.15 | 305.58, 93.62 | -44.02, -31.78 | in-in | in | 8.7536 | Saltbr-in | 2.8397 | HRD-in | -68.48, -48.35 | 74.56, -77.19 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.1944 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -56.65, -39.86 | 999.0, -45.7 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 3.0 | 0.186 | 0.288 | H | 399.0 | 366.0 | 23 | 29 | 14 | 15 | [[92, 354]] | 1.0 | 7p6n | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|