Ligand: 5YO

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7P6QC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC ROCK2 ROCK2_HUMAN 7P6QA O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.3544 13.3521 BLAminus -144.62, 167.8 60.55, 87.07 -103.28, 32.93 301.59, 102.75 -70.91, -20.49 in-in in 8.6243 Saltbr-in 2.7039 HRD-in -68.26, -48.48 72.01, -4.52 in-in-out SNCiio in-out ActLoopNT-in 2.994 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.2 APE8-rot-out 61.47 APE67-dihe-in -43.02, -40.39 -80.11, -25.58 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.89 0.209 0.266 A 399.0 377.0 13 29 17 12 [[92, 354]] 1.0 7p6q AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6QB O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.3 13.3089 BLAminus -144.44, 167.29 60.61, 86.93 -103.67, 32.19 301.37, 101.58 -69.29, -21.55 in-in in 8.6066 Saltbr-in 2.913 HRD-in -66.9, -49.14 71.14, -2.98 in-in-out SNCiio in-out ActLoopNT-in 2.9639 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 125.87 APE8-rot-out 59.05 APE67-dihe-in -44.93, -40.33 -80.35, -26.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.89 0.209 0.266 B 399.0 374.0 15 29 17 12 [[92, 354]] 1.0 7p6q AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6QC O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.2846 13.3478 BLAminus -141.89, 172.56 57.11, 86.76 -103.5, 32.32 300.6, 102.23 -70.12, -20.17 in-in in 8.6371 Saltbr-in 2.9166 HRD-in -68.26, -48.37 71.29, -4.5 in-in-out SNCiio in-out ActLoopNT-in 2.9721 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnio APE10-dihe-na 999.0, 162.63 APE9-dihe-na 97.71, -154.08 APE8-dihe-in -75.95, 125.62 APE8-rot-out 63.5 APE67-dihe-in -42.44, -40.72 -78.86, -26.19 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.9414 APE9-dist-out 7.9957 None None None XRAY 2.89 0.209 0.266 C 399.0 387.0 2 29 27 2 [[92, 354]] 1.0 7p6q AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6QD O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.282 13.2775 BLAminus -144.35, 168.09 60.51, 86.98 -102.62, 32.26 301.67, 102.33 -72.56, -19.6 in-in in 8.6255 Saltbr-in 2.9146 HRD-in -67.92, -48.44 71.11, -3.01 in-in-out SNCiio in-out ActLoopNT-in 2.9762 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -97.55, 159.64 APE9-dihe-na 118.49, 149.2 APE8-dihe-in -71.69, 137.89 APE8-rot-out 54.73 APE67-dihe-in -45.23, -39.33 -77.36, -30.49 APE12-dist-in 12.6103 APE11-dist-in 11.4713 APE10-dist-in 5.7837 APE9-dist-in 5.2067 None None None XRAY 2.89 0.209 0.266 D 399.0 383.0 6 29 27 2 [[92, 354]] 1.0 7p6q AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2

Ligand: 5YO

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7P6QC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC ROCK2 ROCK2_HUMAN 7P6QA O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.3544 13.3521 BLAminus -144.62, 167.8 60.55, 87.07 -103.28, 32.93 301.59, 102.75 -70.91, -20.49 in-in in 8.6243 Saltbr-in 2.7039 HRD-in -68.26, -48.48 72.01, -4.52 in-in-out SNCiio in-out ActLoopNT-in 2.994 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.2 APE8-rot-out 61.47 APE67-dihe-in -43.02, -40.39 -80.11, -25.58 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.89 0.209 0.266 A 399.0 377.0 13 29 17 12 [[92, 354]] 1.0 7p6q Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6QB O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.3 13.3089 BLAminus -144.44, 167.29 60.61, 86.93 -103.67, 32.19 301.37, 101.58 -69.29, -21.55 in-in in 8.6066 Saltbr-in 2.913 HRD-in -66.9, -49.14 71.14, -2.98 in-in-out SNCiio in-out ActLoopNT-in 2.9639 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 125.87 APE8-rot-out 59.05 APE67-dihe-in -44.93, -40.33 -80.35, -26.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.89 0.209 0.266 B 399.0 374.0 15 29 17 12 [[92, 354]] 1.0 7p6q Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6QC O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.2846 13.3478 BLAminus -141.89, 172.56 57.11, 86.76 -103.5, 32.32 300.6, 102.23 -70.12, -20.17 in-in in 8.6371 Saltbr-in 2.9166 HRD-in -68.26, -48.37 71.29, -4.5 in-in-out SNCiio in-out ActLoopNT-in 2.9721 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnio APE10-dihe-na 999.0, 162.63 APE9-dihe-na 97.71, -154.08 APE8-dihe-in -75.95, 125.62 APE8-rot-out 63.5 APE67-dihe-in -42.44, -40.72 -78.86, -26.19 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.9414 APE9-dist-out 7.9957 None None None XRAY 2.89 0.209 0.266 C 399.0 387.0 2 29 27 2 [[92, 354]] 1.0 7p6q Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6QD O75116 24 417 1388.0 5YO:501 Type1 Inactive DFGin 6.282 13.2775 BLAminus -144.35, 168.09 60.51, 86.98 -102.62, 32.26 301.67, 102.33 -72.56, -19.6 in-in in 8.6255 Saltbr-in 2.9146 HRD-in -67.92, -48.44 71.11, -3.01 in-in-out SNCiio in-out ActLoopNT-in 2.9762 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -97.55, 159.64 APE9-dihe-na 118.49, 149.2 APE8-dihe-in -71.69, 137.89 APE8-rot-out 54.73 APE67-dihe-in -45.23, -39.33 -77.36, -30.49 APE12-dist-in 12.6103 APE11-dist-in 11.4713 APE10-dist-in 5.7837 APE9-dist-in 5.2067 None None None XRAY 2.89 0.209 0.266 D 399.0 383.0 6 29 27 2 [[92, 354]] 1.0 7p6q Homo sapiens AGC_ROCK2_HUMAN AGC 2.3e-93 318.0 1.0 260.0 260.0 231 232 233 235 237 121 140 144 211 213 212 214.0 276 260 255 254 253 252 251 250 249 170 Rho-associated protein kinase 2

Ligand: 5YO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name