Ligand: 5U4

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5F20A

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR TYK2-2 TYK2_HUMAN 5F20A 2.91 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5U4 Type1 888 - 1176 0 None None Non-receptor tyrosine-protein kinase TYK2

Ligand: 5U4

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5F20A

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TYK2-2 TYK2_HUMAN 5F20A 2.91 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5U4 Type1 888 - 1176 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

Ligand: 5U4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism