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| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47A | P78368 | 44 | 338 | 415.0 | 5ID:61300 | Type1 | Active | DFGin | 6.313 | 14.64 | BLAminus | -129.51, 170.53 | 64.59, 87.8 | -100.86, 26.45 | 292.82, 85.23 | -61.77, -29.75 | in-in | in | 7.931 | Saltbr-in | 2.762 | HRD-in | -96.4, -53.31 | 67.41, 18.29 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.856 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -129.12, 144.16 | APE9-dihe-na | 130.71, 169.91 | APE8-dihe-in | -87.41, 109.44 | APE8-rot-in | 293.53 | APE67-dihe-in | -64.3, -37.98 | -51.39, -32.12 | APE12-dist-in | 13.265 | APE11-dist-in | 12.427 | APE10-dist-in | 7.515 | APE9-dist-in | 5.131 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | A | 313 | 289 | 6 | 0 | 0 | 0 | [[46, 314]] | 1.0 | 2c47 | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47B | P78368 | 44 | 338 | 415.0 | 5ID:61300 | Type1 | Active | DFGin | 6.311 | 14.691 | BLAminus | -129.31, 171.74 | 68.63, 86.23 | -102.1, 27.46 | 291.19, 100.92 | -63.21, -29.46 | in-in | in | 7.956 | Saltbr-in | 2.807 | HRD-in | -98.17, -49.5 | 61.94, 16.94 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.883 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -130.01, 141.49 | APE9-dihe-na | 135.93, 163.17 | APE8-dihe-in | -82.51, 116.58 | APE8-rot-in | 305.21 | APE67-dihe-in | -63.13, -36.57 | -55.79, -31.0 | APE12-dist-in | 12.828 | APE11-dist-in | 12.36 | APE10-dist-in | 7.656 | APE9-dist-in | 5.024 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | B | 313 | 290 | 5 | 0 | 0 | 0 | [[46, 314]] | 1.0 | 2c47 | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47C | P78368 | 46 | 337 | 415.0 | 5ID:61300 | Type1 | None | DFGin | 6.356 | 14.596 | BLAminus | -130.46, 170.19 | 65.55, 88.27 | -102.77, 30.7 | 296.19, 90.63 | -63.02, -30.33 | in-none | in | 7.865 | Saltbr-none | 999.0 | HRD-in | -98.28, -49.29 | 66.18, 13.24 | none-in-in | SNCnii | in-in | ActLoopNT-in | 2.81 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -130.54, 145.79 | APE9-dihe-na | 130.26, 167.92 | APE8-dihe-in | -84.31, 112.7 | APE8-rot-in | 299.01 | APE67-dihe-in | -60.37, -38.22 | -52.73, -35.19 | APE12-dist-in | 13.224 | APE11-dist-in | 12.469 | APE10-dist-in | 7.664 | APE9-dist-in | 5.033 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | C | 313 | 283 | 9 | 0 | 0 | 0 | [[46, 314]] | 1.0 | 2c47 | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47D | P78368 | 43 | 338 | 415.0 | 5ID:61300 | Type1 | Active | DFGin | 6.369 | 14.679 | BLAminus | -127.86, 168.33 | 69.69, 87.83 | -101.96, 26.04 | 291.76, 83.09 | -63.78, -28.59 | in-in | in | 7.804 | Saltbr-in | 3.284 | HRD-in | -97.58, -49.16 | 65.6, 15.38 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.825 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -125.61, 142.77 | APE9-dihe-na | 131.76, 164.65 | APE8-dihe-in | -83.32, 111.4 | APE8-rot-in | 292.97 | APE67-dihe-in | -63.39, -36.85 | -52.87, -31.96 | APE12-dist-in | 12.973 | APE11-dist-in | 12.452 | APE10-dist-in | 7.367 | APE9-dist-in | 5.073 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | D | 313 | 290 | 6 | 0 | 0 | 1 | [[46, 314]] | 1.0 | 2c47 | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CMGC | CLK1 | CLK1_HUMAN | 6G33A | P49759 | 148 | 482 | 484.0 | 5ID:60501 | Type1 | Inactive | DFGin | 7.039 | 14.029 | BLAminus | -127.31, 176.31 | 68.38, 85.72 | -104.03, 25.47 | 298.82, 93.66 | -74.89, -17.97 | in-in | in | 8.382 | Saltbr-in | 2.725 | HRD-in | -70.1, -50.84 | 78.28, -13.18 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.848 | ActLoopCT-out | nonTYR | APEdihe_aaino | APEdist_oioo | APE10-dihe-na | -128.78, 136.1 | APE9-dihe-na | -77.1, 148.33 | APE8-dihe-in | -66.51, 123.5 | APE8-rot-none | 999.0 | APE67-dihe-out | -66.2, -20.29 | -135.8, 167.22 | APE12-dist-out | 14.701 | APE11-dist-in | 12.354 | APE10-dist-out | 9.499 | APE9-dist-out | 8.8 | None | SEP341,TPO342 | SEP341,TPO342 | XRAY | 2.05 | 0.19 | 0.218 | A | 339 | 335 | 0 | 0 | 0 | 0 | [[161, 477]] | 1.0 | 6g33 | CMGC_CLK1_HUMAN | CMGC | 2.5e-93 | 318.5 | 1 | 301 | 301 | 324 | 325 | 326 | 328 | 330 | 191 | 206 | 210 | 285 | 287 | 286 | 288 | 361 | 349 | 344 | 343 | 342 | 341 | 340 | 339 | 338 | 242 | Dual specificity protein kinase CLK1 |
| CMGC | CLK1 | CLK1_HUMAN | 6G33B | P49759 | 148 | 482 | 484.0 | 5ID:60501 | Type1 | Inactive | DFGin | 7.077 | 13.979 | BLAminus | -125.16, 175.81 | 68.83, 87.13 | -106.27, 24.24 | 297.31, 93.02 | -76.58, -16.07 | in-in | in | 8.386 | Saltbr-in | 2.7 | HRD-in | -69.85, -51.6 | 75.98, -11.49 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.879 | ActLoopCT-out | nonTYR | APEdihe_aaiio | APEdist_iioo | APE10-dihe-na | -123.97, 135.36 | APE9-dihe-na | -72.42, 114.42 | APE8-dihe-in | -42.53, 141.22 | APE8-rot-in | 302.44 | APE67-dihe-out | -66.45, -16.55 | -136.36, 149.49 | APE12-dist-in | 13.884 | APE11-dist-in | 11.906 | APE10-dist-out | 10.349 | APE9-dist-out | 9.743 | None | None | None | XRAY | 2.05 | 0.19 | 0.218 | B | 339 | 335 | 0 | 0 | 0 | 0 | [[161, 477]] | 1.0 | 6g33 | CMGC_CLK1_HUMAN | CMGC | 2.5e-93 | 318.5 | 1 | 301 | 301 | 324 | 325 | 326 | 328 | 330 | 191 | 206 | 210 | 285 | 287 | 286 | 288 | 361 | 349 | 344 | 343 | 342 | 341 | 340 | 339 | 338 | 242 | Dual specificity protein kinase CLK1 |
| CMGC | CLK1 | CLK1_HUMAN | 6G33C | P49759 | 148 | 482 | 484.0 | 5ID:60501 | Type1 | Inactive | DFGin | 7.153 | 14.05 | BLAminus | -127.31, 175.45 | 68.57, 84.45 | -104.42, 25.23 | 297.23, 96.23 | -74.84, -18.72 | in-in | in | 8.43 | Saltbr-in | 2.707 | HRD-in | -68.44, -51.98 | 75.83, -9.76 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.833 | ActLoopCT-out | nonTYR | APEdihe_aaini | APEdist_oioi | APE10-dihe-na | -158.67, 144.43 | APE9-dihe-na | 80.91, 147.02 | APE8-dihe-in | -56.89, 133.87 | APE8-rot-none | 999.0 | APE67-dihe-in | -70.75, -20.64 | -58.82, -30.99 | APE12-dist-out | 14.13 | APE11-dist-in | 11.464 | APE10-dist-out | 8.215 | APE9-dist-in | 3.07 | None | None | None | XRAY | 2.05 | 0.19 | 0.218 | C | 339 | 335 | 0 | 0 | 0 | 0 | [[161, 477]] | 1.0 | 6g33 | CMGC_CLK1_HUMAN | CMGC | 2.5e-93 | 318.5 | 1 | 301 | 301 | 324 | 325 | 326 | 328 | 330 | 191 | 206 | 210 | 285 | 287 | 286 | 288 | 361 | 349 | 344 | 343 | 342 | 341 | 340 | 339 | 338 | 242 | Dual specificity protein kinase CLK1 |
| CMGC | CSNK2A1 | CSK21_HUMAN | 6JWAA | P68400 | 2 | 328 | 391.0 | 5ID:401 | Type1 | Inactive | DFGin | 7.314 | 16.322 | BLAminus | -118.25, -176.85 | 54.81, 78.06 | -96.12, 18.11 | 293.12, 81.85 | -64.69, -21.92 | in-in | in | 9.416 | Saltbr-in | 2.808 | HRD-in | -74.7, -50.79 | 69.14, 11.78 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.895 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -129.39, 169.97 | APE9-dihe-na | 64.81, 154.97 | APE8-dihe-in | -64.61, 144.27 | APE8-rot-out | 155.88 | APE67-dihe-in | -70.41, -16.61 | -43.41, -46.73 | APE12-dist-in | 12.539 | APE11-dist-in | 10.095 | APE10-dist-in | 6.104 | APE9-dist-in | 3.25 | None | None | None | XRAY | 1.781 | 0.187 | 0.225 | A | 340 | 327 | 0 | 0 | 0 | 0 | [[39, 324]] | 1.0 | 6jwa | CMGC_CSNK2A1_HUMAN | CMGC | 1.4e-69 | 240.5 | 1 | 301 | 301 | 174 | 175 | 176 | 178 | 180 | 68 | 81 | 85 | 153 | 155 | 154 | 156 | 214 | 201 | 196 | 195 | 194 | 193 | 192 | 191 | 190 | 114 | Casein kinase II subunit alpha |
| CMGC | MAPK1 | MK01_HUMAN | 8ZJVA | P28482 | 10 | 358 | 360.0 | 5ID:401 | Type1 | Inactive | DFGin | 6.911 | 15.083 | BLAminus | -132.32, -178.04 | 60.39, 69.81 | -88.48, 24.49 | 282.54, 65.61 | -59.28, -29.83 | in-out | in | 9.724 | Saltbr-out | 3.85 | HRD-in | -83.31, -48.81 | 74.28, 2.88 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.723 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -98.6, -35.66 | APE9-dihe-na | -57.94, 156.55 | APE8-dihe-in | -58.22, 132.29 | APE8-rot-in | 307.39 | APE67-dihe-in | -64.79, -16.64 | -58.91, -47.39 | APE12-dist-in | 13.836 | APE11-dist-in | 10.936 | APE10-dist-in | 7.141 | APE9-dist-in | 4.382 | None | None | None | XRAY | 1.8 | 0.192 | 0.22 | A | 351 | 349 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 8zjv | CMGC_MAPK1_HUMAN | CMGC | 8.4e-86 | 293.8 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 5AX3A | P28482 | 10 | 358 | 360.0 | 5ID:60401 | Type1 | Inactive | DFGin | 7.082 | 16.428 | BLAminus | -127.71, -158.49 | 57.95, 57.37 | -96.01, 22.02 | 283.93, 97.26 | -69.96, -43.04 | out-out | out | 10.38 | Saltbr-out | 5.461 | HRD-in | -80.67, -26.64 | 62.8, -46.45 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.68 | ActLoopCT-out | nonTYR | APEdihe_aanii | APEdist_iion | APE10-dihe-na | -119.6, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 86.51 | APE8-rot-in | 343.49 | APE67-dihe-in | -91.22, -8.7 | -96.21, 42.35 | APE12-dist-in | 8.483 | APE11-dist-in | 9.812 | APE10-dist-out | 9.512 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.984 | 0.239 | 0.285 | A | 368 | 329 | 20 | 0 | 0 | 9 | [[25, 313]] | 1.0 | 5ax3 | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7W5OA | P28482 | 11 | 360 | 360.0 | 5ID:401 | Type1 | Inactive | DFGin | 6.726 | 16.074 | BLAminus | -134.06, -178.68 | 57.89, 83.45 | -97.58, 26.47 | 285.78, 74.05 | -62.2, -23.74 | in-out | in | 9.598 | Saltbr-out | 3.664 | HRD-in | -64.25, -57.62 | 81.95, -6.27 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.842 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_ioii | APE10-dihe-na | -125.26, 105.21 | APE9-dihe-na | 77.53, 139.94 | APE8-dihe-in | -62.13, 139.76 | APE8-rot-in | 304.97 | APE67-dihe-in | -67.0, -21.21 | -48.23, -45.39 | APE12-dist-in | 8.898 | APE11-dist-out | 7.52 | APE10-dist-in | 7.667 | APE9-dist-in | 3.055 | None | None | NEP125 | XRAY | 2.35 | 0.228 | 0.279 | A | 368 | 350 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7w5o | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7XC1B | P28482 | 12 | 357 | 360.0 | 5ID:402 | Type1 | Inactive | DFGin | 6.75 | 15.848 | BLAminus | -136.86, 178.87 | 56.25, 81.89 | -92.76, 18.78 | 288.3, 68.54 | -60.11, -21.88 | in-in | in | 9.174 | Saltbr-in | 3.022 | HRD-in | -76.63, -53.91 | 78.34, 9.0 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.708 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_ioii | APE10-dihe-na | -112.15, 106.32 | APE9-dihe-na | 73.8, 141.03 | APE8-dihe-in | -61.74, 138.85 | APE8-rot-in | 297.46 | APE67-dihe-in | -56.69, -24.12 | -44.69, -58.48 | APE12-dist-in | 8.356 | APE11-dist-out | 7.557 | APE10-dist-in | 7.85 | APE9-dist-in | 3.035 | None | None | NEP125 | XRAY | 2.09 | 0.232 | 0.271 | B | 368 | 346 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7xc1 | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7XC1A | P28482 | 10 | 360 | 360.0 | 5ID:401,B8Z:405 | Type1,Allosteric | Inactive | DFGin | 6.708 | 15.976 | BLAminus | -137.71, -179.56 | 58.01, 78.42 | -93.4, 30.18 | 285.99, 69.28 | -65.81, -34.24 | in-in | in | 9.527 | Saltbr-in | 3.0 | HRD-in | -74.95, -51.9 | 73.0, -2.02 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.744 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_ioii | APE10-dihe-na | -122.62, 101.42 | APE9-dihe-na | 74.74, 135.42 | APE8-dihe-in | -55.35, 136.96 | APE8-rot-in | 306.98 | APE67-dihe-in | -57.04, -22.83 | -48.83, -53.13 | APE12-dist-in | 8.712 | APE11-dist-out | 7.512 | APE10-dist-in | 7.787 | APE9-dist-in | 3.016 | None | None | NEP125 | XRAY | 2.09 | 0.232 | 0.271 | A | 368 | 351 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7xc1 | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7X4UA | P28482 | 10 | 359 | 360.0 | 5ID:401,8DK:402,BTB:404 | Type1,Allosteric,Allosteric | Inactive | DFGin | 6.926 | 15.757 | BLAminus | -130.94, 179.99 | 65.43, 75.46 | -94.7, 29.02 | 282.13, 69.46 | -67.73, -25.68 | in-out | in | 9.857 | Saltbr-out | 4.063 | HRD-in | -76.85, -49.01 | 74.24, 2.54 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.695 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -104.34, -27.33 | APE9-dihe-na | -70.01, 158.49 | APE8-dihe-in | -59.37, 130.23 | APE8-rot-in | 310.67 | APE67-dihe-in | -64.33, -17.62 | -55.67, -49.5 | APE12-dist-in | 13.752 | APE11-dist-in | 10.944 | APE10-dist-in | 7.171 | APE9-dist-in | 4.562 | None | None | None | XRAY | 1.98 | 0.199 | 0.235 | A | 368 | 350 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7x4u | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK3 | MK03_HUMAN | 2ZOQA | P27361 | 24 | 375 | 379.0 | 5ID:382 | Type1 | Inactive | DFGin | 6.822 | 14.876 | BLAminus | -110.57, 174.03 | 16.61, 106.79 | -100.79, 23.94 | 292.4, 62.55 | -56.98, -29.52 | in-in | in | 9.223 | Saltbr-in | 2.858 | HRD-in | -74.22, -49.1 | 69.67, -4.29 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.715 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_oiii | APE10-dihe-na | -88.46, -39.85 | APE9-dihe-na | -45.11, 153.81 | APE8-dihe-in | -55.88, 121.07 | APE8-rot-in | 311.89 | APE67-dihe-in | -58.47, -14.87 | -49.12, -49.9 | APE12-dist-out | 14.379 | APE11-dist-in | 9.797 | APE10-dist-in | 6.865 | APE9-dist-in | 4.614 | None | PTR204 | PTR204 | XRAY | 2.39 | 0.249 | 0.267 | A | 382 | 352 | 0 | 0 | 0 | 0 | [[42, 330]] | 1.0 | 2zoq | CMGC_MAPK3_HUMAN | CMGC | 3.2e-87 | 298.5 | 1 | 301 | 301 | 183 | 184 | 185 | 187 | 189 | 71 | 88 | 92 | 163 | 165 | 164 | 166 | 227 | 214 | 209 | 208 | 207 | 206 | 205 | 204 | 203 | 123 | Mitogen-activated protein kinase 3 |
| CMGC | MAPK3 | MK03_HUMAN | 2ZOQB | P27361 | 24 | 375 | 379.0 | 5ID:382 | Type1 | Inactive | DFGin | 7.081 | 14.696 | BLAminus | -126.97, -169.7 | 58.49, 71.36 | -96.75, 32.61 | 283.64, 67.73 | -68.29, -24.37 | in-out | in | 9.648 | Saltbr-out | 3.747 | HRD-in | -67.75, -54.76 | 76.39, 2.97 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.787 | ActLoopCT-out | nonTYR | APEdihe_aaoio | APEdist_iiii | APE10-dihe-na | -62.22, -135.12 | APE9-dihe-na | -49.82, -170.24 | APE8-dihe-out | -38.65, -56.7 | APE8-rot-in | 299.06 | APE67-dihe-out | -72.56, -16.77 | 136.84, -44.19 | APE12-dist-in | 13.667 | APE11-dist-in | 11.413 | APE10-dist-in | 7.869 | APE9-dist-in | 4.076 | None | PTR204 | PTR204 | XRAY | 2.39 | 0.249 | 0.267 | B | 382 | 352 | 0 | 0 | 0 | 0 | [[42, 330]] | 1.0 | 2zoq | CMGC_MAPK3_HUMAN | CMGC | 3.2e-87 | 298.5 | 1 | 301 | 301 | 183 | 184 | 185 | 187 | 189 | 71 | 88 | 92 | 163 | 165 | 164 | 166 | 227 | 214 | 209 | 208 | 207 | 206 | 205 | 204 | 203 | 123 | Mitogen-activated protein kinase 3 |
| OTHER | HASPIN | HASP_HUMAN | 6G39A | Q8TF76 | 471 | 798 | 798.0 | 5ID:802 | Type1 | Active | DFGin | 5.021 | 12.32 | BLAminus | -127.21, 173.16 | 74.1, 91.77 | -104.6, 25.15 | 318.27, 124.04 | -54.52, -37.44 | in-in | in | 9.223 | Saltbr-in | 2.607 | HRD-na-N | -72.86, -48.93 | 72.97, 0.92 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.865 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -116.61, 13.68 | APE9-dihe-na | -74.05, 162.55 | APE8-dihe-na | -147.53, 161.22 | APE8-rot-na | 206.35 | APE67-dihe-na | -163.09, 139.78 | 96.44, 2.71 | APE12-dist-na | 9.496 | APE11-dist-na | 13.491 | APE10-dist-na | 16.919 | APE9-dist-na | 13.026 | F605Y | None | None | XRAY | 1.45 | 0.159 | 0.175 | A | 357 | 328 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 6g39 | OTHER_HASPIN_HUMAN | HASP | 3.9e-226 | 755.1 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 2VUWA | Q8TF76 | 470 | 798 | 798.0 | 5ID:1800 | Type1 | Active | DFGin | 4.977 | 12.344 | BLAminus | -126.7, 172.42 | 73.13, 94.6 | -106.22, 25.34 | 317.03, 123.17 | -59.06, -30.58 | in-in | in | 9.293 | Saltbr-in | 2.791 | HRD-na-N | -69.06, -49.8 | 71.93, -0.86 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.886 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -117.41, 21.25 | APE9-dihe-na | -74.65, 162.69 | APE8-dihe-na | -150.22, 164.21 | APE8-rot-na | 197.92 | APE67-dihe-na | -163.26, 143.62 | 93.5, 5.23 | APE12-dist-na | 9.51 | APE11-dist-na | 13.492 | APE10-dist-na | 17.046 | APE9-dist-na | 12.946 | None | None | MSE615,MSE706,MSE725,MSE752,MSE756,MSE767,MSE781 | XRAY | 1.8 | 0.148 | 0.169 | A | 336 | 329 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 2vuw | OTHER_HASPIN_HUMAN | HASP | 1.1e-226 | 756.9 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 3IQ7A | Q8TF76 | 471 | 798 | 798.0 | 5ID:799 | Type1 | Active | DFGin | 5.002 | 12.525 | BLAminus | -130.14, 168.59 | 78.5, 93.8 | -107.03, 26.88 | 317.14, 123.36 | -63.63, -28.13 | in-in | in | 9.288 | Saltbr-in | 2.716 | HRD-na-N | -69.08, -54.14 | 69.34, 3.59 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.842 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -119.96, 19.66 | APE9-dihe-na | -73.26, 163.53 | APE8-dihe-na | -151.13, 165.69 | APE8-rot-na | 217.79 | APE67-dihe-na | -160.55, 141.37 | 91.74, 4.08 | APE12-dist-na | 9.31 | APE11-dist-na | 13.171 | APE10-dist-na | 16.954 | APE9-dist-na | 12.798 | None | None | None | XRAY | 2.0 | 0.174 | 0.207 | A | 357 | 328 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 3iq7 | OTHER_HASPIN_HUMAN | HASP | 1.4e-226 | 756.6 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 4OUCA | Q8TF76 | 470 | 798 | 798.0 | 5ID:60808 | Type1 | Active | DFGin | 5.142 | 12.398 | BLAminus | -123.14, 171.36 | 70.83, 89.85 | -103.14, 24.75 | 317.85, 126.13 | -50.7, -43.23 | in-in | in | 9.227 | Saltbr-in | 2.635 | HRD-na-N | -73.5, -49.82 | 73.73, 4.15 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.897 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -116.93, 10.97 | APE9-dihe-na | -70.72, 155.25 | APE8-dihe-na | -144.93, 165.92 | APE8-rot-na | 81.62 | APE67-dihe-na | -154.34, 142.15 | 101.34, -0.24 | APE12-dist-na | 9.521 | APE11-dist-na | 13.627 | APE10-dist-na | 17.119 | APE9-dist-na | 12.997 | None | None | None | XRAY | 1.9 | 0.166 | 0.211 | A | 357 | 329 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 4ouc | OTHER_HASPIN_HUMAN | HASP | 1.4e-226 | 756.6 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 6G34A | Q8TF76 | 472 | 798 | 798.0 | 5ID:60401 | Type1 | Active | DFGin | 4.991 | 12.367 | BLAminus | -127.35, 171.15 | 74.89, 93.11 | -104.99, 26.96 | 316.16, 126.1 | -57.37, -32.12 | in-in | in | 9.292 | Saltbr-in | 2.721 | HRD-na-N | -71.53, -47.32 | 70.63, -2.3 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.893 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -117.68, 18.32 | APE9-dihe-na | -70.1, 157.86 | APE8-dihe-na | -146.1, 158.98 | APE8-rot-na | 202.21 | APE67-dihe-na | -162.15, 141.91 | 96.58, 0.13 | APE12-dist-na | 9.436 | APE11-dist-na | 13.462 | APE10-dist-na | 16.952 | APE9-dist-na | 12.837 | None | None | None | XRAY | 1.76 | 0.14 | 0.174 | A | 357 | 327 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 6g34 | OTHER_HASPIN_HUMAN | HASP | 1.4e-226 | 756.6 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 6G3AA | Q8TF76 | 471 | 798 | 798.0 | 5ID:805 | Type1 | Inactive | DFGin | 4.953 | 12.443 | BLAminus | -127.41, 171.94 | 74.51, 93.23 | -106.28, 26.81 | 312.44, 123.45 | -60.95, -29.67 | in-out | in | 9.904 | Saltbr-out | 4.42 | HRD-na-N | -72.27, -48.82 | 73.62, 1.17 | out-in-na | SNCoia | in-na | ActLoopNT-in | 2.883 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -116.57, 14.66 | APE9-dihe-na | -70.85, 159.17 | APE8-dihe-na | -152.35, 172.74 | APE8-rot-na | 72.92 | APE67-dihe-na | -156.95, 142.2 | 92.44, -2.34 | APE12-dist-na | 9.454 | APE11-dist-na | 13.382 | APE10-dist-na | 16.931 | APE9-dist-na | 12.993 | F605T | None | None | XRAY | 1.43 | 0.151 | 0.175 | A | 357 | 328 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 6g3a | OTHER_HASPIN_HUMAN | HASP | 1.8e-225 | 752.9 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47A | P78368 | 44 | 338 | 415.0 | 5ID:61300 | Type1 | Active | DFGin | 6.313 | 14.64 | BLAminus | -129.51, 170.53 | 64.59, 87.8 | -100.86, 26.45 | 292.82, 85.23 | -61.77, -29.75 | in-in | in | 7.931 | Saltbr-in | 2.762 | HRD-in | -96.4, -53.31 | 67.41, 18.29 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.856 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -129.12, 144.16 | APE9-dihe-na | 130.71, 169.91 | APE8-dihe-in | -87.41, 109.44 | APE8-rot-in | 293.53 | APE67-dihe-in | -64.3, -37.98 | -51.39, -32.12 | APE12-dist-in | 13.265 | APE11-dist-in | 12.427 | APE10-dist-in | 7.515 | APE9-dist-in | 5.131 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | A | 313 | 289 | 6 | 0 | 0 | 0 | [[46, 314]] | 1.0 | 2c47 | Homo sapiens | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47B | P78368 | 44 | 338 | 415.0 | 5ID:61300 | Type1 | Active | DFGin | 6.311 | 14.691 | BLAminus | -129.31, 171.74 | 68.63, 86.23 | -102.1, 27.46 | 291.19, 100.92 | -63.21, -29.46 | in-in | in | 7.956 | Saltbr-in | 2.807 | HRD-in | -98.17, -49.5 | 61.94, 16.94 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.883 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -130.01, 141.49 | APE9-dihe-na | 135.93, 163.17 | APE8-dihe-in | -82.51, 116.58 | APE8-rot-in | 305.21 | APE67-dihe-in | -63.13, -36.57 | -55.79, -31.0 | APE12-dist-in | 12.828 | APE11-dist-in | 12.36 | APE10-dist-in | 7.656 | APE9-dist-in | 5.024 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | B | 313 | 290 | 5 | 0 | 0 | 0 | [[46, 314]] | 1.0 | 2c47 | Homo sapiens | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47C | P78368 | 46 | 337 | 415.0 | 5ID:61300 | Type1 | None | DFGin | 6.356 | 14.596 | BLAminus | -130.46, 170.19 | 65.55, 88.27 | -102.77, 30.7 | 296.19, 90.63 | -63.02, -30.33 | in-none | in | 7.865 | Saltbr-none | 999.0 | HRD-in | -98.28, -49.29 | 66.18, 13.24 | none-in-in | SNCnii | in-in | ActLoopNT-in | 2.81 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -130.54, 145.79 | APE9-dihe-na | 130.26, 167.92 | APE8-dihe-in | -84.31, 112.7 | APE8-rot-in | 299.01 | APE67-dihe-in | -60.37, -38.22 | -52.73, -35.19 | APE12-dist-in | 13.224 | APE11-dist-in | 12.469 | APE10-dist-in | 7.664 | APE9-dist-in | 5.033 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | C | 313 | 283 | 9 | 0 | 0 | 0 | [[46, 314]] | 1.0 | 2c47 | Homo sapiens | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CK1 | CSNK1G2 | KC1G2_HUMAN | 2C47D | P78368 | 43 | 338 | 415.0 | 5ID:61300 | Type1 | Active | DFGin | 6.369 | 14.679 | BLAminus | -127.86, 168.33 | 69.69, 87.83 | -101.96, 26.04 | 291.76, 83.09 | -63.78, -28.59 | in-in | in | 7.804 | Saltbr-in | 3.284 | HRD-in | -97.58, -49.16 | 65.6, 15.38 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.825 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -125.61, 142.77 | APE9-dihe-na | 131.76, 164.65 | APE8-dihe-in | -83.32, 111.4 | APE8-rot-in | 292.97 | APE67-dihe-in | -63.39, -36.85 | -52.87, -31.96 | APE12-dist-in | 12.973 | APE11-dist-in | 12.452 | APE10-dist-in | 7.367 | APE9-dist-in | 5.073 | None | None | CSD111 | XRAY | 2.4 | 0.211 | 0.257 | D | 313 | 290 | 6 | 0 | 0 | 1 | [[46, 314]] | 1.0 | 2c47 | Homo sapiens | CK1_CSNK1G2_HUMAN | CK1 | 1.5e-117 | 397.6 | 1 | 261 | 261 | 187 | 188 | 189 | 191 | 193 | 75 | 89 | 93 | 162 | 164 | 163 | 165 | 234 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 120 | Casein kinase I isoform gamma-2 |
| CMGC | CLK1 | CLK1_HUMAN | 6G33A | P49759 | 148 | 482 | 484.0 | 5ID:60501 | Type1 | Inactive | DFGin | 7.039 | 14.029 | BLAminus | -127.31, 176.31 | 68.38, 85.72 | -104.03, 25.47 | 298.82, 93.66 | -74.89, -17.97 | in-in | in | 8.382 | Saltbr-in | 2.725 | HRD-in | -70.1, -50.84 | 78.28, -13.18 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.848 | ActLoopCT-out | nonTYR | APEdihe_aaino | APEdist_oioo | APE10-dihe-na | -128.78, 136.1 | APE9-dihe-na | -77.1, 148.33 | APE8-dihe-in | -66.51, 123.5 | APE8-rot-none | 999.0 | APE67-dihe-out | -66.2, -20.29 | -135.8, 167.22 | APE12-dist-out | 14.701 | APE11-dist-in | 12.354 | APE10-dist-out | 9.499 | APE9-dist-out | 8.8 | None | SEP341,TPO342 | SEP341,TPO342 | XRAY | 2.05 | 0.19 | 0.218 | A | 339 | 335 | 0 | 0 | 0 | 0 | [[161, 477]] | 1.0 | 6g33 | Homo sapiens | CMGC_CLK1_HUMAN | CMGC | 2.5e-93 | 318.5 | 1 | 301 | 301 | 324 | 325 | 326 | 328 | 330 | 191 | 206 | 210 | 285 | 287 | 286 | 288 | 361 | 349 | 344 | 343 | 342 | 341 | 340 | 339 | 338 | 242 | Dual specificity protein kinase CLK1 |
| CMGC | CLK1 | CLK1_HUMAN | 6G33B | P49759 | 148 | 482 | 484.0 | 5ID:60501 | Type1 | Inactive | DFGin | 7.077 | 13.979 | BLAminus | -125.16, 175.81 | 68.83, 87.13 | -106.27, 24.24 | 297.31, 93.02 | -76.58, -16.07 | in-in | in | 8.386 | Saltbr-in | 2.7 | HRD-in | -69.85, -51.6 | 75.98, -11.49 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.879 | ActLoopCT-out | nonTYR | APEdihe_aaiio | APEdist_iioo | APE10-dihe-na | -123.97, 135.36 | APE9-dihe-na | -72.42, 114.42 | APE8-dihe-in | -42.53, 141.22 | APE8-rot-in | 302.44 | APE67-dihe-out | -66.45, -16.55 | -136.36, 149.49 | APE12-dist-in | 13.884 | APE11-dist-in | 11.906 | APE10-dist-out | 10.349 | APE9-dist-out | 9.743 | None | None | None | XRAY | 2.05 | 0.19 | 0.218 | B | 339 | 335 | 0 | 0 | 0 | 0 | [[161, 477]] | 1.0 | 6g33 | Homo sapiens | CMGC_CLK1_HUMAN | CMGC | 2.5e-93 | 318.5 | 1 | 301 | 301 | 324 | 325 | 326 | 328 | 330 | 191 | 206 | 210 | 285 | 287 | 286 | 288 | 361 | 349 | 344 | 343 | 342 | 341 | 340 | 339 | 338 | 242 | Dual specificity protein kinase CLK1 |
| CMGC | CLK1 | CLK1_HUMAN | 6G33C | P49759 | 148 | 482 | 484.0 | 5ID:60501 | Type1 | Inactive | DFGin | 7.153 | 14.05 | BLAminus | -127.31, 175.45 | 68.57, 84.45 | -104.42, 25.23 | 297.23, 96.23 | -74.84, -18.72 | in-in | in | 8.43 | Saltbr-in | 2.707 | HRD-in | -68.44, -51.98 | 75.83, -9.76 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.833 | ActLoopCT-out | nonTYR | APEdihe_aaini | APEdist_oioi | APE10-dihe-na | -158.67, 144.43 | APE9-dihe-na | 80.91, 147.02 | APE8-dihe-in | -56.89, 133.87 | APE8-rot-none | 999.0 | APE67-dihe-in | -70.75, -20.64 | -58.82, -30.99 | APE12-dist-out | 14.13 | APE11-dist-in | 11.464 | APE10-dist-out | 8.215 | APE9-dist-in | 3.07 | None | None | None | XRAY | 2.05 | 0.19 | 0.218 | C | 339 | 335 | 0 | 0 | 0 | 0 | [[161, 477]] | 1.0 | 6g33 | Homo sapiens | CMGC_CLK1_HUMAN | CMGC | 2.5e-93 | 318.5 | 1 | 301 | 301 | 324 | 325 | 326 | 328 | 330 | 191 | 206 | 210 | 285 | 287 | 286 | 288 | 361 | 349 | 344 | 343 | 342 | 341 | 340 | 339 | 338 | 242 | Dual specificity protein kinase CLK1 |
| CMGC | CSNK2A1 | CSK21_HUMAN | 6JWAA | P68400 | 2 | 328 | 391.0 | 5ID:401 | Type1 | Inactive | DFGin | 7.314 | 16.322 | BLAminus | -118.25, -176.85 | 54.81, 78.06 | -96.12, 18.11 | 293.12, 81.85 | -64.69, -21.92 | in-in | in | 9.416 | Saltbr-in | 2.808 | HRD-in | -74.7, -50.79 | 69.14, 11.78 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.895 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -129.39, 169.97 | APE9-dihe-na | 64.81, 154.97 | APE8-dihe-in | -64.61, 144.27 | APE8-rot-out | 155.88 | APE67-dihe-in | -70.41, -16.61 | -43.41, -46.73 | APE12-dist-in | 12.539 | APE11-dist-in | 10.095 | APE10-dist-in | 6.104 | APE9-dist-in | 3.25 | None | None | None | XRAY | 1.781 | 0.187 | 0.225 | A | 340 | 327 | 0 | 0 | 0 | 0 | [[39, 324]] | 1.0 | 6jwa | Homo sapiens | CMGC_CSNK2A1_HUMAN | CMGC | 1.4e-69 | 240.5 | 1 | 301 | 301 | 174 | 175 | 176 | 178 | 180 | 68 | 81 | 85 | 153 | 155 | 154 | 156 | 214 | 201 | 196 | 195 | 194 | 193 | 192 | 191 | 190 | 114 | Casein kinase II subunit alpha |
| CMGC | MAPK1 | MK01_HUMAN | 8ZJVA | P28482 | 10 | 358 | 360.0 | 5ID:401 | Type1 | Inactive | DFGin | 6.911 | 15.083 | BLAminus | -132.32, -178.04 | 60.39, 69.81 | -88.48, 24.49 | 282.54, 65.61 | -59.28, -29.83 | in-out | in | 9.724 | Saltbr-out | 3.85 | HRD-in | -83.31, -48.81 | 74.28, 2.88 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.723 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -98.6, -35.66 | APE9-dihe-na | -57.94, 156.55 | APE8-dihe-in | -58.22, 132.29 | APE8-rot-in | 307.39 | APE67-dihe-in | -64.79, -16.64 | -58.91, -47.39 | APE12-dist-in | 13.836 | APE11-dist-in | 10.936 | APE10-dist-in | 7.141 | APE9-dist-in | 4.382 | None | None | None | XRAY | 1.8 | 0.192 | 0.22 | A | 351 | 349 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 8zjv | Homo sapiens | CMGC_MAPK1_HUMAN | CMGC | 8.4e-86 | 293.8 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 5AX3A | P28482 | 10 | 358 | 360.0 | 5ID:60401 | Type1 | Inactive | DFGin | 7.082 | 16.428 | BLAminus | -127.71, -158.49 | 57.95, 57.37 | -96.01, 22.02 | 283.93, 97.26 | -69.96, -43.04 | out-out | out | 10.38 | Saltbr-out | 5.461 | HRD-in | -80.67, -26.64 | 62.8, -46.45 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.68 | ActLoopCT-out | nonTYR | APEdihe_aanii | APEdist_iion | APE10-dihe-na | -119.6, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 86.51 | APE8-rot-in | 343.49 | APE67-dihe-in | -91.22, -8.7 | -96.21, 42.35 | APE12-dist-in | 8.483 | APE11-dist-in | 9.812 | APE10-dist-out | 9.512 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.984 | 0.239 | 0.285 | A | 368 | 329 | 20 | 0 | 0 | 9 | [[25, 313]] | 1.0 | 5ax3 | Homo sapiens | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7W5OA | P28482 | 11 | 360 | 360.0 | 5ID:401 | Type1 | Inactive | DFGin | 6.726 | 16.074 | BLAminus | -134.06, -178.68 | 57.89, 83.45 | -97.58, 26.47 | 285.78, 74.05 | -62.2, -23.74 | in-out | in | 9.598 | Saltbr-out | 3.664 | HRD-in | -64.25, -57.62 | 81.95, -6.27 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.842 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_ioii | APE10-dihe-na | -125.26, 105.21 | APE9-dihe-na | 77.53, 139.94 | APE8-dihe-in | -62.13, 139.76 | APE8-rot-in | 304.97 | APE67-dihe-in | -67.0, -21.21 | -48.23, -45.39 | APE12-dist-in | 8.898 | APE11-dist-out | 7.52 | APE10-dist-in | 7.667 | APE9-dist-in | 3.055 | None | None | NEP125 | XRAY | 2.35 | 0.228 | 0.279 | A | 368 | 350 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7w5o | Homo sapiens | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7XC1B | P28482 | 12 | 357 | 360.0 | 5ID:402 | Type1 | Inactive | DFGin | 6.75 | 15.848 | BLAminus | -136.86, 178.87 | 56.25, 81.89 | -92.76, 18.78 | 288.3, 68.54 | -60.11, -21.88 | in-in | in | 9.174 | Saltbr-in | 3.022 | HRD-in | -76.63, -53.91 | 78.34, 9.0 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.708 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_ioii | APE10-dihe-na | -112.15, 106.32 | APE9-dihe-na | 73.8, 141.03 | APE8-dihe-in | -61.74, 138.85 | APE8-rot-in | 297.46 | APE67-dihe-in | -56.69, -24.12 | -44.69, -58.48 | APE12-dist-in | 8.356 | APE11-dist-out | 7.557 | APE10-dist-in | 7.85 | APE9-dist-in | 3.035 | None | None | NEP125 | XRAY | 2.09 | 0.232 | 0.271 | B | 368 | 346 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7xc1 | Homo sapiens | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7XC1A | P28482 | 10 | 360 | 360.0 | 5ID:401,B8Z:405 | Type1,Allosteric | Inactive | DFGin | 6.708 | 15.976 | BLAminus | -137.71, -179.56 | 58.01, 78.42 | -93.4, 30.18 | 285.99, 69.28 | -65.81, -34.24 | in-in | in | 9.527 | Saltbr-in | 3.0 | HRD-in | -74.95, -51.9 | 73.0, -2.02 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.744 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_ioii | APE10-dihe-na | -122.62, 101.42 | APE9-dihe-na | 74.74, 135.42 | APE8-dihe-in | -55.35, 136.96 | APE8-rot-in | 306.98 | APE67-dihe-in | -57.04, -22.83 | -48.83, -53.13 | APE12-dist-in | 8.712 | APE11-dist-out | 7.512 | APE10-dist-in | 7.787 | APE9-dist-in | 3.016 | None | None | NEP125 | XRAY | 2.09 | 0.232 | 0.271 | A | 368 | 351 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7xc1 | Homo sapiens | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK1 | MK01_HUMAN | 7X4UA | P28482 | 10 | 359 | 360.0 | 5ID:401,8DK:402,BTB:404 | Type1,Allosteric,Allosteric | Inactive | DFGin | 6.926 | 15.757 | BLAminus | -130.94, 179.99 | 65.43, 75.46 | -94.7, 29.02 | 282.13, 69.46 | -67.73, -25.68 | in-out | in | 9.857 | Saltbr-out | 4.063 | HRD-in | -76.85, -49.01 | 74.24, 2.54 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.695 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -104.34, -27.33 | APE9-dihe-na | -70.01, 158.49 | APE8-dihe-in | -59.37, 130.23 | APE8-rot-in | 310.67 | APE67-dihe-in | -64.33, -17.62 | -55.67, -49.5 | APE12-dist-in | 13.752 | APE11-dist-in | 10.944 | APE10-dist-in | 7.171 | APE9-dist-in | 4.562 | None | None | None | XRAY | 1.98 | 0.199 | 0.235 | A | 368 | 350 | 0 | 0 | 0 | 0 | [[25, 313]] | 1.0 | 7x4u | Homo sapiens | CMGC_MAPK1_HUMAN | CMGC | 9.9e-86 | 293.6 | 1 | 301 | 301 | 166 | 167 | 168 | 170 | 172 | 54 | 71 | 75 | 146 | 148 | 147 | 149 | 210 | 197 | 192 | 191 | 190 | 189 | 188 | 187 | 186 | 106 | Mitogen-activated protein kinase 1 |
| CMGC | MAPK3 | MK03_HUMAN | 2ZOQA | P27361 | 24 | 375 | 379.0 | 5ID:382 | Type1 | Inactive | DFGin | 6.822 | 14.876 | BLAminus | -110.57, 174.03 | 16.61, 106.79 | -100.79, 23.94 | 292.4, 62.55 | -56.98, -29.52 | in-in | in | 9.223 | Saltbr-in | 2.858 | HRD-in | -74.22, -49.1 | 69.67, -4.29 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.715 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_oiii | APE10-dihe-na | -88.46, -39.85 | APE9-dihe-na | -45.11, 153.81 | APE8-dihe-in | -55.88, 121.07 | APE8-rot-in | 311.89 | APE67-dihe-in | -58.47, -14.87 | -49.12, -49.9 | APE12-dist-out | 14.379 | APE11-dist-in | 9.797 | APE10-dist-in | 6.865 | APE9-dist-in | 4.614 | None | PTR204 | PTR204 | XRAY | 2.39 | 0.249 | 0.267 | A | 382 | 352 | 0 | 0 | 0 | 0 | [[42, 330]] | 1.0 | 2zoq | Homo sapiens | CMGC_MAPK3_HUMAN | CMGC | 3.2e-87 | 298.5 | 1 | 301 | 301 | 183 | 184 | 185 | 187 | 189 | 71 | 88 | 92 | 163 | 165 | 164 | 166 | 227 | 214 | 209 | 208 | 207 | 206 | 205 | 204 | 203 | 123 | Mitogen-activated protein kinase 3 |
| CMGC | MAPK3 | MK03_HUMAN | 2ZOQB | P27361 | 24 | 375 | 379.0 | 5ID:382 | Type1 | Inactive | DFGin | 7.081 | 14.696 | BLAminus | -126.97, -169.7 | 58.49, 71.36 | -96.75, 32.61 | 283.64, 67.73 | -68.29, -24.37 | in-out | in | 9.648 | Saltbr-out | 3.747 | HRD-in | -67.75, -54.76 | 76.39, 2.97 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.787 | ActLoopCT-out | nonTYR | APEdihe_aaoio | APEdist_iiii | APE10-dihe-na | -62.22, -135.12 | APE9-dihe-na | -49.82, -170.24 | APE8-dihe-out | -38.65, -56.7 | APE8-rot-in | 299.06 | APE67-dihe-out | -72.56, -16.77 | 136.84, -44.19 | APE12-dist-in | 13.667 | APE11-dist-in | 11.413 | APE10-dist-in | 7.869 | APE9-dist-in | 4.076 | None | PTR204 | PTR204 | XRAY | 2.39 | 0.249 | 0.267 | B | 382 | 352 | 0 | 0 | 0 | 0 | [[42, 330]] | 1.0 | 2zoq | Homo sapiens | CMGC_MAPK3_HUMAN | CMGC | 3.2e-87 | 298.5 | 1 | 301 | 301 | 183 | 184 | 185 | 187 | 189 | 71 | 88 | 92 | 163 | 165 | 164 | 166 | 227 | 214 | 209 | 208 | 207 | 206 | 205 | 204 | 203 | 123 | Mitogen-activated protein kinase 3 |
| OTHER | HASPIN | HASP_HUMAN | 6G39A | Q8TF76 | 471 | 798 | 798.0 | 5ID:802 | Type1 | Active | DFGin | 5.021 | 12.32 | BLAminus | -127.21, 173.16 | 74.1, 91.77 | -104.6, 25.15 | 318.27, 124.04 | -54.52, -37.44 | in-in | in | 9.223 | Saltbr-in | 2.607 | HRD-na-N | -72.86, -48.93 | 72.97, 0.92 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.865 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -116.61, 13.68 | APE9-dihe-na | -74.05, 162.55 | APE8-dihe-na | -147.53, 161.22 | APE8-rot-na | 206.35 | APE67-dihe-na | -163.09, 139.78 | 96.44, 2.71 | APE12-dist-na | 9.496 | APE11-dist-na | 13.491 | APE10-dist-na | 16.919 | APE9-dist-na | 13.026 | F605Y | None | None | XRAY | 1.45 | 0.159 | 0.175 | A | 357 | 328 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 6g39 | Homo sapiens | OTHER_HASPIN_HUMAN | HASP | 3.9e-226 | 755.1 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 2VUWA | Q8TF76 | 470 | 798 | 798.0 | 5ID:1800 | Type1 | Active | DFGin | 4.977 | 12.344 | BLAminus | -126.7, 172.42 | 73.13, 94.6 | -106.22, 25.34 | 317.03, 123.17 | -59.06, -30.58 | in-in | in | 9.293 | Saltbr-in | 2.791 | HRD-na-N | -69.06, -49.8 | 71.93, -0.86 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.886 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -117.41, 21.25 | APE9-dihe-na | -74.65, 162.69 | APE8-dihe-na | -150.22, 164.21 | APE8-rot-na | 197.92 | APE67-dihe-na | -163.26, 143.62 | 93.5, 5.23 | APE12-dist-na | 9.51 | APE11-dist-na | 13.492 | APE10-dist-na | 17.046 | APE9-dist-na | 12.946 | None | None | MSE615,MSE706,MSE725,MSE752,MSE756,MSE767,MSE781 | XRAY | 1.8 | 0.148 | 0.169 | A | 336 | 329 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 2vuw | Homo sapiens | OTHER_HASPIN_HUMAN | HASP | 1.1e-226 | 756.9 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 3IQ7A | Q8TF76 | 471 | 798 | 798.0 | 5ID:799 | Type1 | Active | DFGin | 5.002 | 12.525 | BLAminus | -130.14, 168.59 | 78.5, 93.8 | -107.03, 26.88 | 317.14, 123.36 | -63.63, -28.13 | in-in | in | 9.288 | Saltbr-in | 2.716 | HRD-na-N | -69.08, -54.14 | 69.34, 3.59 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.842 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -119.96, 19.66 | APE9-dihe-na | -73.26, 163.53 | APE8-dihe-na | -151.13, 165.69 | APE8-rot-na | 217.79 | APE67-dihe-na | -160.55, 141.37 | 91.74, 4.08 | APE12-dist-na | 9.31 | APE11-dist-na | 13.171 | APE10-dist-na | 16.954 | APE9-dist-na | 12.798 | None | None | None | XRAY | 2.0 | 0.174 | 0.207 | A | 357 | 328 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 3iq7 | Homo sapiens | OTHER_HASPIN_HUMAN | HASP | 1.4e-226 | 756.6 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 4OUCA | Q8TF76 | 470 | 798 | 798.0 | 5ID:60808 | Type1 | Active | DFGin | 5.142 | 12.398 | BLAminus | -123.14, 171.36 | 70.83, 89.85 | -103.14, 24.75 | 317.85, 126.13 | -50.7, -43.23 | in-in | in | 9.227 | Saltbr-in | 2.635 | HRD-na-N | -73.5, -49.82 | 73.73, 4.15 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.897 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -116.93, 10.97 | APE9-dihe-na | -70.72, 155.25 | APE8-dihe-na | -144.93, 165.92 | APE8-rot-na | 81.62 | APE67-dihe-na | -154.34, 142.15 | 101.34, -0.24 | APE12-dist-na | 9.521 | APE11-dist-na | 13.627 | APE10-dist-na | 17.119 | APE9-dist-na | 12.997 | None | None | None | XRAY | 1.9 | 0.166 | 0.211 | A | 357 | 329 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 4ouc | Homo sapiens | OTHER_HASPIN_HUMAN | HASP | 1.4e-226 | 756.6 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 6G34A | Q8TF76 | 472 | 798 | 798.0 | 5ID:60401 | Type1 | Active | DFGin | 4.991 | 12.367 | BLAminus | -127.35, 171.15 | 74.89, 93.11 | -104.99, 26.96 | 316.16, 126.1 | -57.37, -32.12 | in-in | in | 9.292 | Saltbr-in | 2.721 | HRD-na-N | -71.53, -47.32 | 70.63, -2.3 | in-in-na | SNCiia | in-na | ActLoopNT-in | 2.893 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -117.68, 18.32 | APE9-dihe-na | -70.1, 157.86 | APE8-dihe-na | -146.1, 158.98 | APE8-rot-na | 202.21 | APE67-dihe-na | -162.15, 141.91 | 96.58, 0.13 | APE12-dist-na | 9.436 | APE11-dist-na | 13.462 | APE10-dist-na | 16.952 | APE9-dist-na | 12.837 | None | None | None | XRAY | 1.76 | 0.14 | 0.174 | A | 357 | 327 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 6g34 | Homo sapiens | OTHER_HASPIN_HUMAN | HASP | 1.4e-226 | 756.6 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| OTHER | HASPIN | HASP_HUMAN | 6G3AA | Q8TF76 | 471 | 798 | 798.0 | 5ID:805 | Type1 | Inactive | DFGin | 4.953 | 12.443 | BLAminus | -127.41, 171.94 | 74.51, 93.23 | -106.28, 26.81 | 312.44, 123.45 | -60.95, -29.67 | in-out | in | 9.904 | Saltbr-out | 4.42 | HRD-na-N | -72.27, -48.82 | 73.62, 1.17 | out-in-na | SNCoia | in-na | ActLoopNT-in | 2.883 | ActLoopCT-na | noAPE | APEdihe_aaaaa | APEdist_aaaa | APE10-dihe-na | -116.57, 14.66 | APE9-dihe-na | -70.85, 159.17 | APE8-dihe-na | -152.35, 172.74 | APE8-rot-na | 72.92 | APE67-dihe-na | -156.95, 142.2 | 92.44, -2.34 | APE12-dist-na | 9.454 | APE11-dist-na | 13.382 | APE10-dist-na | 16.931 | APE9-dist-na | 12.993 | F605T | None | None | XRAY | 1.43 | 0.151 | 0.175 | A | 357 | 328 | 0 | 0 | 0 | 0 | [[484, 797]] | 1.0 | 6g3a | Homo sapiens | OTHER_HASPIN_HUMAN | HASP | 1.8e-225 | 752.9 | 1 | 314 | 314 | 686 | 687 | 688 | 690 | 692 | 511 | 535 | 539 | 646 | 648 | 647 | 649 | 741 | 721 | 716 | 715 | 714 | 713 | 712 | 711 | 710 | 604 | Serine/threonine-protein kinase haspin |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
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