Ligand: 4UQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 5BPYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 5BPYA Q06187 396 657 659.0 4UQ:64000 Type1 Inactive DFGin 6.3602 13.3055 BLBplus -124.65, 164.88 51.29, 37.75 -70.0, 127.36 35.13, 98.17 69.78, 12.96 out-out out 15.0418 Saltbr-out 16.1326 HRD-in -71.75, -58.49 82.06, -15.91 out-out-out SNCooo out-out ActLoopNT-out 7.8951 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -111.29, -6.51 APE9-dihe-in -62.22, 139.35 APE8-dihe-in -81.26, 69.56 APE8-rot-na 30.14 APE67-dihe-in -66.47, -13.16 -61.31, -41.9 APE12-dist-na 17.2653 APE11-dist-na 19.274 APE10-dist-na 14.23 APE9-dist-out 8.7636 None None None XRAY 2.31 0.215 0.242 A 267.0 262.0 0 29 29 0 [[402, 653]] 1.0 5bpy TYR_BTK_HUMAN TYR 5.7e-93 316.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BPYB Q06187 396 657 659.0 4UQ:64000 Type1 Inactive DFGin 6.0407 13.3553 BLBplus -124.21, 164.45 49.48, 38.96 -70.05, 125.98 33.54, 98.82 68.93, 10.8 out-none out 14.6981 Saltbr-none 999.0 HRD-in -73.63, -56.78 81.23, -14.54 none-out-out SNCnoo out-out ActLoopNT-out 7.9375 ActLoopCT-out TYR APEdihe_nooai APEdist_aaao APE10-dihe-none 999.0, -33.35 APE9-dihe-out -59.81, -45.04 APE8-dihe-out -62.46, 0.27 APE8-rot-na 341.31 APE67-dihe-in -65.96, -13.01 -56.63, -35.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 18.1618 APE9-dist-out 11.0675 None None None XRAY 2.31 0.215 0.242 B 267.0 246.0 16 29 18 11 [[402, 653]] 1.0 5bpy TYR_BTK_HUMAN TYR 5.7e-93 316.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 4UQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 5BPYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 5BPYA Q06187 396 657 659.0 4UQ:64000 Type1 Inactive DFGin 6.3602 13.3055 BLBplus -124.65, 164.88 51.29, 37.75 -70.0, 127.36 35.13, 98.17 69.78, 12.96 out-out out 15.0418 Saltbr-out 16.1326 HRD-in -71.75, -58.49 82.06, -15.91 out-out-out SNCooo out-out ActLoopNT-out 7.8951 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -111.29, -6.51 APE9-dihe-in -62.22, 139.35 APE8-dihe-in -81.26, 69.56 APE8-rot-na 30.14 APE67-dihe-in -66.47, -13.16 -61.31, -41.9 APE12-dist-na 17.2653 APE11-dist-na 19.274 APE10-dist-na 14.23 APE9-dist-out 8.7636 None None None XRAY 2.31 0.215 0.242 A 267.0 262.0 0 29 29 0 [[402, 653]] 1.0 5bpy Homo sapiens TYR_BTK_HUMAN TYR 5.7e-93 316.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BPYB Q06187 396 657 659.0 4UQ:64000 Type1 Inactive DFGin 6.0407 13.3553 BLBplus -124.21, 164.45 49.48, 38.96 -70.05, 125.98 33.54, 98.82 68.93, 10.8 out-none out 14.6981 Saltbr-none 999.0 HRD-in -73.63, -56.78 81.23, -14.54 none-out-out SNCnoo out-out ActLoopNT-out 7.9375 ActLoopCT-out TYR APEdihe_nooai APEdist_aaao APE10-dihe-none 999.0, -33.35 APE9-dihe-out -59.81, -45.04 APE8-dihe-out -62.46, 0.27 APE8-rot-na 341.31 APE67-dihe-in -65.96, -13.01 -56.63, -35.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 18.1618 APE9-dist-out 11.0675 None None None XRAY 2.31 0.215 0.242 B 267.0 246.0 16 29 18 11 [[402, 653]] 1.0 5bpy Homo sapiens TYR_BTK_HUMAN TYR 5.7e-93 316.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 4UQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name