Ligand: 3WH

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4X21B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 4X21A P53779 46 400 464.0 3WH:501 Type1 Inactive DFGin 3.8772 14.0841 ABAminus -86.15, -29.47 -144.69, -176.02 -119.22, 12.33 302.12, 89.55 63.86, -139.07 in-in in 9.3621 Saltbr-in 2.8907 HRD-in -67.92, -54.72 67.34, -6.59 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 131.48 APE8-dihe-in -96.56, 122.08 APE8-rot-out 53.42 APE67-dihe-in -63.39, -15.55 -110.05, 4.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.4858 None None None XRAY 1.95 0.201 0.224 A 367.0 336.0 14 27 13 14 [[64, 359]] 1.0 4x21 CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4X21B P53779 47 400 464.0 3WH:501 Type1 Inactive DFGin 3.9172 14.2155 ABAminus -86.96, -29.76 -145.94, -175.14 -114.66, 15.37 298.36, 95.81 78.31, -160.57 in-in in 9.0417 Saltbr-in 2.8165 HRD-in -68.55, -57.06 69.42, -2.62 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 131.49 APE8-dihe-in -93.23, 121.56 APE8-rot-out 53.27 APE67-dihe-in -59.62, -14.73 -109.14, 8.1 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.1005 None None None XRAY 1.95 0.201 0.224 B 367.0 336.0 13 27 14 13 [[64, 359]] 1.0 4x21 CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: 3WH

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4X21B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 4X21A P53779 46 400 464.0 3WH:501 Type1 Inactive DFGin 3.8772 14.0841 ABAminus -86.15, -29.47 -144.69, -176.02 -119.22, 12.33 302.12, 89.55 63.86, -139.07 in-in in 9.3621 Saltbr-in 2.8907 HRD-in -67.92, -54.72 67.34, -6.59 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 131.48 APE8-dihe-in -96.56, 122.08 APE8-rot-out 53.42 APE67-dihe-in -63.39, -15.55 -110.05, 4.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.4858 None None None XRAY 1.95 0.201 0.224 A 367.0 336.0 14 27 13 14 [[64, 359]] 1.0 4x21 Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4X21B P53779 47 400 464.0 3WH:501 Type1 Inactive DFGin 3.9172 14.2155 ABAminus -86.96, -29.76 -145.94, -175.14 -114.66, 15.37 298.36, 95.81 78.31, -160.57 in-in in 9.0417 Saltbr-in 2.8165 HRD-in -68.55, -57.06 69.42, -2.62 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 131.49 APE8-dihe-in -93.23, 121.56 APE8-rot-out 53.27 APE67-dihe-in -59.62, -14.73 -109.14, 8.1 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.1005 None None None XRAY 1.95 0.201 0.224 B 367.0 336.0 13 27 14 13 [[64, 359]] 1.0 4x21 Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: 3WH

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name