Ligand: 3O4

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4BBEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK2-2 JAK2_HUMAN 4BBEA 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBEB 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBEC 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBED 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2

Ligand: 3O4

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4BBEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK2-2 JAK2_HUMAN 4BBEA 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4BBEB 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4BBEC 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4BBED 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2 Homo sapiens

Ligand: 3O4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism