Ligand: 3FF

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6ZQSA
DFGin None 1 50.0% 3QUEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 6ZQSA Q16539 4 353 360.0 3FF:400 Type1 Inactive DFGin 7.1312 15.0067 BLAminus -100.05, 172.92 58.72, 89.64 -100.69, 26.63 286.71, 76.86 -66.14, -26.38 out-out out 10.2824 Saltbr-out 3.9201 HRD-in -83.97, -53.39 74.81, 10.18 out-in-in SNCoii in-in ActLoopNT-in 2.8547 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.23, 173.02 APE9-dihe-na 73.87, 161.94 APE8-dihe-in -91.46, 139.33 APE8-rot-in 294.96 APE67-dihe-in -66.05, -18.45 -53.95, -45.87 APE12-dist-in 11.599 APE11-dist-in 11.174 APE10-dist-in 6.7713 APE9-dist-in 3.0458 None TPO180,PTR182 TPO180,PTR182 XRAY 1.95 0.178 0.223 A 362.0 350.0 0 25 25 0 [[24, 308]] 1.0 6zqs CMGC_MAPK14_HUMAN CMGC 6e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3QUEA Q16539 5 353 360.0 3FF:362 Type1 Inactive DFGin 10.6415 12.3386 None -82.41, 155.86 -75.27, -54.23 -130.98, 134.23 308.77, 88.25 -97.08, -170.31 in-in in 8.9604 Saltbr-in 2.6567 HRD-in -64.83, -54.13 86.66, -27.06 in-out-out SNCioo out-out ActLoopNT-out 21.2792 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 66.84 APE9-dihe-na -77.78, 135.56 APE8-dihe-out -48.89, -54.16 APE8-rot-in 280.74 APE67-dihe-in -53.38, -25.8 -51.95, -34.65 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.1952 APE9-dist-out 11.3927 None None None XRAY 2.7 0.23 0.311 A 360.0 343.0 6 25 19 6 [[24, 308]] 1.0 3que CMGC_MAPK14_HUMAN CMGC 5.9e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: 3FF

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6ZQSA
DFGin None 1 50.0% 3QUEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 6ZQSA Q16539 4 353 360.0 3FF:400 Type1 Inactive DFGin 7.1312 15.0067 BLAminus -100.05, 172.92 58.72, 89.64 -100.69, 26.63 286.71, 76.86 -66.14, -26.38 out-out out 10.2824 Saltbr-out 3.9201 HRD-in -83.97, -53.39 74.81, 10.18 out-in-in SNCoii in-in ActLoopNT-in 2.8547 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.23, 173.02 APE9-dihe-na 73.87, 161.94 APE8-dihe-in -91.46, 139.33 APE8-rot-in 294.96 APE67-dihe-in -66.05, -18.45 -53.95, -45.87 APE12-dist-in 11.599 APE11-dist-in 11.174 APE10-dist-in 6.7713 APE9-dist-in 3.0458 None TPO180,PTR182 TPO180,PTR182 XRAY 1.95 0.178 0.223 A 362.0 350.0 0 25 25 0 [[24, 308]] 1.0 6zqs Homo sapiens CMGC_MAPK14_HUMAN CMGC 6e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3QUEA Q16539 5 353 360.0 3FF:362 Type1 Inactive DFGin 10.6415 12.3386 None -82.41, 155.86 -75.27, -54.23 -130.98, 134.23 308.77, 88.25 -97.08, -170.31 in-in in 8.9604 Saltbr-in 2.6567 HRD-in -64.83, -54.13 86.66, -27.06 in-out-out SNCioo out-out ActLoopNT-out 21.2792 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 66.84 APE9-dihe-na -77.78, 135.56 APE8-dihe-out -48.89, -54.16 APE8-rot-in 280.74 APE67-dihe-in -53.38, -25.8 -51.95, -34.65 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.1952 APE9-dist-out 11.3927 None None None XRAY 2.7 0.23 0.311 A 360.0 343.0 6 25 19 6 [[24, 308]] 1.0 3que Homo sapiens CMGC_MAPK14_HUMAN CMGC 5.9e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: 3FF

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name