Ligand: 36H

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7F7WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 7F7WA O60674 536 810 1132.0 36H:1000 Type1 Pseudo DFGin 6.915 13.7962 None -91.54, 171.73 -67.57, 155.24 -69.34, -22.33 351.29, 21.05 78.83, -168.1 out-na out 10.1693 Saltbr-na 999.0 HRD-in -84.02, -62.23 90.48, 0.05 na-out-out SNCaoo out-out ActLoopNT-out 9.7232 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -68.04, -35.76 APE9-dihe-out -66.77, -25.16 APE8-dihe-out -85.21, 3.67 APE8-rot-na 284.34 APE67-dihe-out -100.56, 25.85 -66.38, 135.35 APE12-dist-na 9.6893 APE11-dist-na 11.4731 APE10-dist-na 16.0322 APE9-dist-out 12.6531 None None None XRAY 1.83 0.208 0.238 A 275.0 275.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7f7w TYR_JAK2-1_HUMAN TYR 5.3e-64 222.0 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7F7WB O60674 536 810 1132.0 36H:1000 Type1 Pseudo DFGin 6.9033 13.6869 None -84.95, 175.07 -74.42, 156.63 -70.62, -23.21 351.87, 21.25 77.0, -167.15 out-na out 10.2517 Saltbr-na 999.0 HRD-in -79.03, -66.0 95.6, -1.12 na-out-out SNCaoo out-out ActLoopNT-out 9.4951 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -68.33, -37.68 APE9-dihe-out -69.53, -21.97 APE8-dihe-out -87.12, 4.19 APE8-rot-na 285.11 APE67-dihe-out -99.09, 24.95 -67.63, 136.04 APE12-dist-na 9.7044 APE11-dist-na 11.4907 APE10-dist-na 16.0173 APE9-dist-out 12.671 None None None XRAY 1.83 0.208 0.238 B 275.0 275.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7f7w TYR_JAK2-1_HUMAN TYR 5.3e-64 222.0 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

Ligand: 36H

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7F7WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 7F7WA O60674 536 810 1132.0 36H:1000 Type1 Pseudo DFGin 6.915 13.7962 None -91.54, 171.73 -67.57, 155.24 -69.34, -22.33 351.29, 21.05 78.83, -168.1 out-na out 10.1693 Saltbr-na 999.0 HRD-in -84.02, -62.23 90.48, 0.05 na-out-out SNCaoo out-out ActLoopNT-out 9.7232 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -68.04, -35.76 APE9-dihe-out -66.77, -25.16 APE8-dihe-out -85.21, 3.67 APE8-rot-na 284.34 APE67-dihe-out -100.56, 25.85 -66.38, 135.35 APE12-dist-na 9.6893 APE11-dist-na 11.4731 APE10-dist-na 16.0322 APE9-dist-out 12.6531 None None None XRAY 1.83 0.208 0.238 A 275.0 275.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7f7w Homo sapiens TYR_JAK2-1_HUMAN TYR 5.3e-64 222.0 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7F7WB O60674 536 810 1132.0 36H:1000 Type1 Pseudo DFGin 6.9033 13.6869 None -84.95, 175.07 -74.42, 156.63 -70.62, -23.21 351.87, 21.25 77.0, -167.15 out-na out 10.2517 Saltbr-na 999.0 HRD-in -79.03, -66.0 95.6, -1.12 na-out-out SNCaoo out-out ActLoopNT-out 9.4951 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -68.33, -37.68 APE9-dihe-out -69.53, -21.97 APE8-dihe-out -87.12, 4.19 APE8-rot-na 285.11 APE67-dihe-out -99.09, 24.95 -67.63, 136.04 APE12-dist-na 9.7044 APE11-dist-na 11.4907 APE10-dist-na 16.0173 APE9-dist-out 12.671 None None None XRAY 1.83 0.208 0.238 B 275.0 275.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7f7w Homo sapiens TYR_JAK2-1_HUMAN TYR 5.3e-64 222.0 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

Ligand: 36H

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name