Ligand: 2VL

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 5P9FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 4OTFA Q06187 396 657 659.0 2VL:60704 Type1 Inactive DFGin 6.1809 13.7558 BLBplus -118.16, 151.16 61.72, 28.57 -55.11, 129.8 38.1, 96.01 83.0, -13.47 out-out out 16.4557 Saltbr-out 16.2069 HRD-in -75.92, -56.91 83.51, -16.44 out-out-out SNCooo out-out ActLoopNT-out 7.7345 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -103.77, -4.68 APE9-dihe-in -64.45, 137.09 APE8-dihe-in -77.9, 61.16 APE8-rot-na 31.4 APE67-dihe-in -69.89, -12.66 -52.32, -42.22 APE12-dist-na 17.474 APE11-dist-na 19.1296 APE10-dist-na 13.8482 APE9-dist-out 8.5545 None None OCS481 XRAY 1.95 0.167 0.203 A 271.0 262.0 0 29 29 0 [[402, 653]] 1.0 4otf TYR_BTK_HUMAN TYR 6e-93 316.8 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9FA Q06187 394 659 659.0 2VL:701 Type1 Inactive DFGin 6.6211 13.7553 BLBplus -119.02, 151.22 61.15, 24.35 -53.19, 127.83 42.31, 92.54 85.51, -16.73 out-out out 14.4003 Saltbr-out 15.0261 HRD-in -75.39, -58.81 80.41, -9.12 out-out-out SNCooo out-out ActLoopNT-out 8.005 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -107.51, 4.62 APE9-dihe-in -72.87, 137.83 APE8-dihe-in -76.24, 65.65 APE8-rot-na 33.67 APE67-dihe-in -72.92, -8.6 -57.83, -44.5 APE12-dist-na 17.3063 APE11-dist-na 18.6164 APE10-dist-na 13.6802 APE9-dist-out 8.3054 None None None XRAY 1.71 0.15 0.223 A 279.0 266.0 0 29 29 0 [[402, 653]] 1.0 5p9f TYR_BTK_HUMAN TYR 6.7e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 2VL

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 5P9FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 4OTFA Q06187 396 657 659.0 2VL:60704 Type1 Inactive DFGin 6.1809 13.7558 BLBplus -118.16, 151.16 61.72, 28.57 -55.11, 129.8 38.1, 96.01 83.0, -13.47 out-out out 16.4557 Saltbr-out 16.2069 HRD-in -75.92, -56.91 83.51, -16.44 out-out-out SNCooo out-out ActLoopNT-out 7.7345 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -103.77, -4.68 APE9-dihe-in -64.45, 137.09 APE8-dihe-in -77.9, 61.16 APE8-rot-na 31.4 APE67-dihe-in -69.89, -12.66 -52.32, -42.22 APE12-dist-na 17.474 APE11-dist-na 19.1296 APE10-dist-na 13.8482 APE9-dist-out 8.5545 None None OCS481 XRAY 1.95 0.167 0.203 A 271.0 262.0 0 29 29 0 [[402, 653]] 1.0 4otf Homo sapiens TYR_BTK_HUMAN TYR 6e-93 316.8 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9FA Q06187 394 659 659.0 2VL:701 Type1 Inactive DFGin 6.6211 13.7553 BLBplus -119.02, 151.22 61.15, 24.35 -53.19, 127.83 42.31, 92.54 85.51, -16.73 out-out out 14.4003 Saltbr-out 15.0261 HRD-in -75.39, -58.81 80.41, -9.12 out-out-out SNCooo out-out ActLoopNT-out 8.005 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -107.51, 4.62 APE9-dihe-in -72.87, 137.83 APE8-dihe-in -76.24, 65.65 APE8-rot-na 33.67 APE67-dihe-in -72.92, -8.6 -57.83, -44.5 APE12-dist-na 17.3063 APE11-dist-na 18.6164 APE10-dist-na 13.6802 APE9-dist-out 8.3054 None None None XRAY 1.71 0.15 0.223 A 279.0 266.0 0 29 29 0 [[402, 653]] 1.0 5p9f Homo sapiens TYR_BTK_HUMAN TYR 6.7e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 2VL

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name