Ligand: 2P5

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 4NWMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 4NWMA Q06187 396 657 659.0 2P5:60701 Type1 Inactive DFGin 6.2366 13.5473 BLBplus -124.36, 162.2 58.0, 30.8 -65.9, 131.67 37.39, 93.38 75.76, -5.81 out-none out 15.7388 Saltbr-none 999.0 HRD-in -75.22, -56.08 81.81, -11.35 none-out-out SNCnoo out-out ActLoopNT-out 7.4406 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -104.06, -3.18 APE9-dihe-in -62.5, 137.94 APE8-dihe-in -76.17, 67.69 APE8-rot-na 29.81 APE67-dihe-in -67.16, -10.51 -55.62, -44.66 APE12-dist-na 17.5081 APE11-dist-na 19.1435 APE10-dist-na 14.0443 APE9-dist-out 8.5218 None None OCS481 XRAY 2.03 0.197 0.234 A 263.0 261.0 1 29 29 0 [[402, 653]] 1.0 4nwm TYR_BTK_HUMAN TYR 5.4e-93 317.0 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4NWMB Q06187 396 657 659.0 2P5:60701 Type1 Inactive DFGin 6.136 13.8027 BLBplus -123.62, 161.4 58.54, 30.74 -65.95, 131.21 37.43, 94.6 74.49, -3.43 out-none out 14.7614 Saltbr-none 999.0 HRD-in -74.43, -56.79 83.89, -12.84 none-out-out SNCnoo out-out ActLoopNT-out 7.4869 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -104.71, -3.65 APE9-dihe-in -64.14, 139.49 APE8-dihe-in -76.31, 69.39 APE8-rot-na 29.79 APE67-dihe-in -66.98, -8.96 -53.75, -47.41 APE12-dist-na 17.2896 APE11-dist-na 19.1988 APE10-dist-na 14.1826 APE9-dist-out 8.4816 None None OCS481 XRAY 2.03 0.197 0.234 B 263.0 261.0 1 29 29 0 [[402, 653]] 1.0 4nwm TYR_BTK_HUMAN TYR 5.4e-93 317.0 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 2P5

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 4NWMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 4NWMA Q06187 396 657 659.0 2P5:60701 Type1 Inactive DFGin 6.2366 13.5473 BLBplus -124.36, 162.2 58.0, 30.8 -65.9, 131.67 37.39, 93.38 75.76, -5.81 out-none out 15.7388 Saltbr-none 999.0 HRD-in -75.22, -56.08 81.81, -11.35 none-out-out SNCnoo out-out ActLoopNT-out 7.4406 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -104.06, -3.18 APE9-dihe-in -62.5, 137.94 APE8-dihe-in -76.17, 67.69 APE8-rot-na 29.81 APE67-dihe-in -67.16, -10.51 -55.62, -44.66 APE12-dist-na 17.5081 APE11-dist-na 19.1435 APE10-dist-na 14.0443 APE9-dist-out 8.5218 None None OCS481 XRAY 2.03 0.197 0.234 A 263.0 261.0 1 29 29 0 [[402, 653]] 1.0 4nwm Homo sapiens TYR_BTK_HUMAN TYR 5.4e-93 317.0 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4NWMB Q06187 396 657 659.0 2P5:60701 Type1 Inactive DFGin 6.136 13.8027 BLBplus -123.62, 161.4 58.54, 30.74 -65.95, 131.21 37.43, 94.6 74.49, -3.43 out-none out 14.7614 Saltbr-none 999.0 HRD-in -74.43, -56.79 83.89, -12.84 none-out-out SNCnoo out-out ActLoopNT-out 7.4869 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -104.71, -3.65 APE9-dihe-in -64.14, 139.49 APE8-dihe-in -76.31, 69.39 APE8-rot-na 29.79 APE67-dihe-in -66.98, -8.96 -53.75, -47.41 APE12-dist-na 17.2896 APE11-dist-na 19.1988 APE10-dist-na 14.1826 APE9-dist-out 8.4816 None None OCS481 XRAY 2.03 0.197 0.234 B 263.0 261.0 1 29 29 0 [[402, 653]] 1.0 4nwm Homo sapiens TYR_BTK_HUMAN TYR 5.4e-93 317.0 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: 2P5

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name