Ligand: 1Q4

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4K77A

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK1-2 JAK1_HUMAN 4K77A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77B 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1

Ligand: 1Q4

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4K77A

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK1-2 JAK1_HUMAN 4K77A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4K77B 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens

Ligand: 1Q4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism