Ligand: 1M8

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 4KINB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 4KINA Q16539 5 352 360.0 1M8:401 Type1 Inactive DFGin 5.8298 14.4907 BLBplus -112.0, 159.56 58.84, 31.67 -80.2, 161.77 51.23, 91.19 70.21, 3.94 in-in in 9.3321 Saltbr-in 2.6928 HRD-in -75.58, -60.36 79.72, -18.44 in-out-out SNCioo out-out ActLoopNT-out 7.8786 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_nooo APE10-dihe-na -81.36, 45.06 APE9-dihe-na -160.68, 148.72 APE8-dihe-in -80.55, 140.18 APE8-rot-out 52.55 APE67-dihe-out -62.92, -22.56 -122.89, 54.77 APE12-dist-none 999.0 APE11-dist-out 19.6485 APE10-dist-out 19.6951 APE9-dist-out 12.8871 None None None XRAY 1.97 0.186 0.217 A 366.0 338.0 10 25 17 8 [[24, 308]] 1.0 4kin CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINB Q16539 4 352 360.0 1M8:401 Type1 Inactive DFGin 5.8331 14.3759 BLBplus -111.81, 160.82 58.79, 31.15 -82.0, 162.48 50.94, 86.22 67.7, 5.09 in-in in 9.2716 Saltbr-in 2.7051 HRD-in -77.44, -59.82 78.53, -17.64 in-out-out SNCioo out-out ActLoopNT-out 8.1687 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -117.05, 92.32 APE9-dihe-na -152.42, 131.25 APE8-dihe-in -58.54, 143.39 APE8-rot-out 65.06 APE67-dihe-in -56.63, -20.78 -125.76, 48.86 APE12-dist-none 999.0 APE11-dist-out 19.6528 APE10-dist-out 21.2323 APE9-dist-out 13.1311 None None None XRAY 1.97 0.186 0.217 B 366.0 341.0 8 25 17 8 [[24, 308]] 1.0 4kin CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINC Q16539 4 352 360.0 1M8:401 Type1 Inactive DFGin 5.8223 14.3313 BLBplus -112.14, 159.92 56.39, 32.68 -82.61, 164.95 50.22, 87.86 66.13, 5.77 in-in in 9.2196 Saltbr-in 2.6995 HRD-in -77.09, -60.2 79.61, -18.38 in-out-out SNCioo out-out ActLoopNT-out 8.1313 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -157.85 APE8-dihe-in -67.36, 151.26 APE8-rot-out 182.89 APE67-dihe-in -64.44, -23.22 -157.89, 24.71 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.7995 None None None XRAY 1.97 0.186 0.217 C 366.0 338.0 11 25 16 9 [[24, 308]] 1.0 4kin CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIND Q16539 4 354 360.0 1M8:401 Type1 Inactive DFGin 5.8375 13.9246 BLBplus -113.2, 160.86 57.37, 29.91 -79.52, 159.49 50.89, 87.6 72.34, 0.42 in-in in 8.8613 Saltbr-in 2.7368 HRD-in -76.52, -60.3 80.07, -18.04 in-out-out SNCioo out-out ActLoopNT-out 8.1205 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 62.74 APE8-dihe-in -59.81, 147.68 APE8-rot-out 180.07 APE67-dihe-in -62.05, -22.47 -108.39, 8.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.4245 None None None XRAY 1.97 0.186 0.217 D 366.0 339.0 12 25 16 9 [[24, 308]] 1.0 4kin CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: 1M8

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 4KINB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 4KINA Q16539 5 352 360.0 1M8:401 Type1 Inactive DFGin 5.8298 14.4907 BLBplus -112.0, 159.56 58.84, 31.67 -80.2, 161.77 51.23, 91.19 70.21, 3.94 in-in in 9.3321 Saltbr-in 2.6928 HRD-in -75.58, -60.36 79.72, -18.44 in-out-out SNCioo out-out ActLoopNT-out 7.8786 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_nooo APE10-dihe-na -81.36, 45.06 APE9-dihe-na -160.68, 148.72 APE8-dihe-in -80.55, 140.18 APE8-rot-out 52.55 APE67-dihe-out -62.92, -22.56 -122.89, 54.77 APE12-dist-none 999.0 APE11-dist-out 19.6485 APE10-dist-out 19.6951 APE9-dist-out 12.8871 None None None XRAY 1.97 0.186 0.217 A 366.0 338.0 10 25 17 8 [[24, 308]] 1.0 4kin Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINB Q16539 4 352 360.0 1M8:401 Type1 Inactive DFGin 5.8331 14.3759 BLBplus -111.81, 160.82 58.79, 31.15 -82.0, 162.48 50.94, 86.22 67.7, 5.09 in-in in 9.2716 Saltbr-in 2.7051 HRD-in -77.44, -59.82 78.53, -17.64 in-out-out SNCioo out-out ActLoopNT-out 8.1687 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -117.05, 92.32 APE9-dihe-na -152.42, 131.25 APE8-dihe-in -58.54, 143.39 APE8-rot-out 65.06 APE67-dihe-in -56.63, -20.78 -125.76, 48.86 APE12-dist-none 999.0 APE11-dist-out 19.6528 APE10-dist-out 21.2323 APE9-dist-out 13.1311 None None None XRAY 1.97 0.186 0.217 B 366.0 341.0 8 25 17 8 [[24, 308]] 1.0 4kin Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINC Q16539 4 352 360.0 1M8:401 Type1 Inactive DFGin 5.8223 14.3313 BLBplus -112.14, 159.92 56.39, 32.68 -82.61, 164.95 50.22, 87.86 66.13, 5.77 in-in in 9.2196 Saltbr-in 2.6995 HRD-in -77.09, -60.2 79.61, -18.38 in-out-out SNCioo out-out ActLoopNT-out 8.1313 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -157.85 APE8-dihe-in -67.36, 151.26 APE8-rot-out 182.89 APE67-dihe-in -64.44, -23.22 -157.89, 24.71 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.7995 None None None XRAY 1.97 0.186 0.217 C 366.0 338.0 11 25 16 9 [[24, 308]] 1.0 4kin Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIND Q16539 4 354 360.0 1M8:401 Type1 Inactive DFGin 5.8375 13.9246 BLBplus -113.2, 160.86 57.37, 29.91 -79.52, 159.49 50.89, 87.6 72.34, 0.42 in-in in 8.8613 Saltbr-in 2.7368 HRD-in -76.52, -60.3 80.07, -18.04 in-out-out SNCioo out-out ActLoopNT-out 8.1205 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 62.74 APE8-dihe-in -59.81, 147.68 APE8-rot-out 180.07 APE67-dihe-in -62.05, -22.47 -108.39, 8.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.4245 None None None XRAY 1.97 0.186 0.217 D 366.0 339.0 12 25 16 9 [[24, 308]] 1.0 4kin Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: 1M8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name