Ligand: 1J6

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4IVCB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4IVCA P23458 854 1154 1154.0 1J6:61201 Type1 Inactive DFGin 6.2486 13.2512 ABAminus -114.51, 9.81 -157.21, 145.73 -138.3, 37.36 304.45, 81.48 -64.22, -30.51 in-in in 7.8262 Saltbr-in 2.6917 HRD-in -91.76, -42.16 67.22, -0.09 in-in-out SNCiio in-out ActLoopNT-in 2.8419 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.76, 45.97 APE9-dihe-in -72.9, 142.32 APE8-dihe-in -77.97, 76.61 APE8-rot-na 30.79 APE67-dihe-in -73.52, -3.32 -54.87, -39.45 APE12-dist-na 11.1918 APE11-dist-na 12.6517 APE10-dist-na 10.1709 APE9-dist-in 6.5489 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.35 0.2 0.263 A 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivc TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVCB P23458 865 1154 1154.0 1J6:61201 Type1 Inactive DFGin 6.3131 13.3466 ABAminus -119.67, 6.43 -149.04, 145.44 -134.49, 29.55 297.17, 82.22 -60.5, -32.79 in-in in 7.5246 Saltbr-in 2.2767 HRD-in -89.31, -45.09 71.21, 3.65 in-in-out SNCiio in-out ActLoopNT-in 2.7171 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -101.71, 20.54 APE9-dihe-in -65.21, 135.06 APE8-dihe-in -79.05, 83.59 APE8-rot-na 28.99 APE67-dihe-in -78.13, -7.38 -62.67, -27.87 APE12-dist-na 11.123 APE11-dist-na 12.804 APE10-dist-na 9.574 APE9-dist-in 6.6074 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.35 0.2 0.263 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivc TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 1J6

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4IVCB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4IVCA P23458 854 1154 1154.0 1J6:61201 Type1 Inactive DFGin 6.2486 13.2512 ABAminus -114.51, 9.81 -157.21, 145.73 -138.3, 37.36 304.45, 81.48 -64.22, -30.51 in-in in 7.8262 Saltbr-in 2.6917 HRD-in -91.76, -42.16 67.22, -0.09 in-in-out SNCiio in-out ActLoopNT-in 2.8419 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.76, 45.97 APE9-dihe-in -72.9, 142.32 APE8-dihe-in -77.97, 76.61 APE8-rot-na 30.79 APE67-dihe-in -73.52, -3.32 -54.87, -39.45 APE12-dist-na 11.1918 APE11-dist-na 12.6517 APE10-dist-na 10.1709 APE9-dist-in 6.5489 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.35 0.2 0.263 A 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivc Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVCB P23458 865 1154 1154.0 1J6:61201 Type1 Inactive DFGin 6.3131 13.3466 ABAminus -119.67, 6.43 -149.04, 145.44 -134.49, 29.55 297.17, 82.22 -60.5, -32.79 in-in in 7.5246 Saltbr-in 2.2767 HRD-in -89.31, -45.09 71.21, 3.65 in-in-out SNCiio in-out ActLoopNT-in 2.7171 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -101.71, 20.54 APE9-dihe-in -65.21, 135.06 APE8-dihe-in -79.05, 83.59 APE8-rot-na 28.99 APE67-dihe-in -78.13, -7.38 -62.67, -27.87 APE12-dist-na 11.123 APE11-dist-na 12.804 APE10-dist-na 9.574 APE9-dist-in 6.6074 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.35 0.2 0.263 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivc Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 1J6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name