Ligand: 0XH

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4GJ2A
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR TYK2-2 TYK2_HUMAN 4GJ2A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0XH Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2

Ligand: 0XH

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4GJ2A
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TYK2-2 TYK2_HUMAN 4GJ2A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0XH Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

Ligand: 0XH

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism