Ligand: 0UN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 7ZYNA
DFGin ABAminus 1 33.3% 3IKAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3IKAA P00533 696 1020 1210.0 0UN:1797 Type1 Inactive DFGin 5.7776 14.3544 ABAminus -126.08, -29.6 -103.63, 124.88 -119.83, 2.06 294.25, 104.41 -43.93, -35.44 in-in in 9.4422 Saltbr-in 3.2201 HRD-in -72.42, -49.2 76.65, -5.52 in-in-in SNCiii in-in ActLoopNT-in 2.9099 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -121.67, 130.5 APE9-dihe-in -133.91, 150.07 APE8-dihe-in -89.48, 105.4 APE8-rot-na 32.64 APE67-dihe-in -62.96, -1.82 -70.92, -51.09 APE12-dist-na 11.0816 APE11-dist-na 9.1284 APE10-dist-na 9.9399 APE9-dist-in 6.7425 T790M None None XRAY 2.9 0.21 0.257 A 331.0 310.0 0 30 30 0 [[712, 970]] 1.0 3ika TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2KA P00533 696 1020 1210.0 0UN:1101 Type1 Active DFGin 6.2518 15.4016 BLAminus -162.18, -166.94 57.57, 64.19 -89.05, 1.52 298.25, 111.15 -60.1, -40.29 in-in in 8.3767 Saltbr-in 3.2309 HRD-in -63.42, -47.14 78.88, -6.86 in-in-in SNCiii in-in ActLoopNT-in 2.7308 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.48, 127.33 APE9-dihe-in -122.09, 137.71 APE8-dihe-in -92.31, 106.07 APE8-rot-na 35.16 APE67-dihe-in -60.76, -39.83 -65.9, -37.9 APE12-dist-na 13.7192 APE11-dist-na 11.8401 APE10-dist-na 11.7833 APE9-dist-in 7.9573 T790M None None XRAY 3.201 0.227 0.244 A 327.0 314.0 8 30 24 6 [[712, 970]] 1.0 5x2k TYR_EGFR_HUMAN TYR 8e-88 300.2 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYNA P00533 697 1018 1210.0 0UN:1101 Type1 Active DFGin 5.8962 15.0459 BLAminus -145.65, -166.89 58.05, 78.44 -95.11, 31.85 294.9, 83.85 -65.75, -30.64 in-in in 8.4425 Saltbr-in 2.894 HRD-in -73.97, -47.38 70.32, 2.73 in-in-in SNCiii in-in ActLoopNT-in 2.8987 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.42, 134.47 APE9-dihe-in -142.75, 146.34 APE8-dihe-in -74.74, 108.36 APE8-rot-na 25.93 APE67-dihe-in -69.45, -12.52 -69.08, -37.0 APE12-dist-na 12.4223 APE11-dist-na 9.1781 APE10-dist-na 10.4792 APE9-dist-in 6.5537 T790M,C797S,E865A,E866A,K867A None None XRAY 2.3 0.193 0.223 A 333.0 317.0 4 30 30 0 [[712, 970]] 1.0 7zyn TYR_EGFR_HUMAN TYR 3.4e-87 298.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 0UN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 7ZYNA
DFGin ABAminus 1 33.3% 3IKAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3IKAA P00533 696 1020 1210.0 0UN:1797 Type1 Inactive DFGin 5.7776 14.3544 ABAminus -126.08, -29.6 -103.63, 124.88 -119.83, 2.06 294.25, 104.41 -43.93, -35.44 in-in in 9.4422 Saltbr-in 3.2201 HRD-in -72.42, -49.2 76.65, -5.52 in-in-in SNCiii in-in ActLoopNT-in 2.9099 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -121.67, 130.5 APE9-dihe-in -133.91, 150.07 APE8-dihe-in -89.48, 105.4 APE8-rot-na 32.64 APE67-dihe-in -62.96, -1.82 -70.92, -51.09 APE12-dist-na 11.0816 APE11-dist-na 9.1284 APE10-dist-na 9.9399 APE9-dist-in 6.7425 T790M None None XRAY 2.9 0.21 0.257 A 331.0 310.0 0 30 30 0 [[712, 970]] 1.0 3ika Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2KA P00533 696 1020 1210.0 0UN:1101 Type1 Active DFGin 6.2518 15.4016 BLAminus -162.18, -166.94 57.57, 64.19 -89.05, 1.52 298.25, 111.15 -60.1, -40.29 in-in in 8.3767 Saltbr-in 3.2309 HRD-in -63.42, -47.14 78.88, -6.86 in-in-in SNCiii in-in ActLoopNT-in 2.7308 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.48, 127.33 APE9-dihe-in -122.09, 137.71 APE8-dihe-in -92.31, 106.07 APE8-rot-na 35.16 APE67-dihe-in -60.76, -39.83 -65.9, -37.9 APE12-dist-na 13.7192 APE11-dist-na 11.8401 APE10-dist-na 11.7833 APE9-dist-in 7.9573 T790M None None XRAY 3.201 0.227 0.244 A 327.0 314.0 8 30 24 6 [[712, 970]] 1.0 5x2k Homo sapiens TYR_EGFR_HUMAN TYR 8e-88 300.2 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYNA P00533 697 1018 1210.0 0UN:1101 Type1 Active DFGin 5.8962 15.0459 BLAminus -145.65, -166.89 58.05, 78.44 -95.11, 31.85 294.9, 83.85 -65.75, -30.64 in-in in 8.4425 Saltbr-in 2.894 HRD-in -73.97, -47.38 70.32, 2.73 in-in-in SNCiii in-in ActLoopNT-in 2.8987 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.42, 134.47 APE9-dihe-in -142.75, 146.34 APE8-dihe-in -74.74, 108.36 APE8-rot-na 25.93 APE67-dihe-in -69.45, -12.52 -69.08, -37.0 APE12-dist-na 12.4223 APE11-dist-na 9.1781 APE10-dist-na 10.4792 APE9-dist-in 6.5537 T790M,C797S,E865A,E866A,K867A None None XRAY 2.3 0.193 0.223 A 333.0 317.0 4 30 30 0 [[712, 970]] 1.0 7zyn Homo sapiens TYR_EGFR_HUMAN TYR 3.4e-87 298.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 0UN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name