Ligand: 0UN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 7ZYNA
DFGin ABAminus 1 33.3% 3IKAA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3IKAA P00533 696 1020 1210.0 0UN:1797 Type1 Inactive DFGin 5.778 14.354 ABAminus -126.08, -29.6 -103.63, 124.88 -119.83, 2.06 294.25, 104.41 -43.93, -35.44 in-in in 9.442 Saltbr-in 3.22 HRD-in -72.42, -49.2 76.65, -5.52 in-in-in SNCiii in-in ActLoopNT-in 2.91 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -121.67, 130.5 APE9-dihe-in -133.91, 150.07 APE8-dihe-in -89.48, 105.4 APE8-rot-na 32.64 APE67-dihe-in -62.96, -1.82 -70.92, -51.09 APE12-dist-na 11.082 APE11-dist-na 9.128 APE10-dist-na 9.94 APE9-dist-in 6.742 T790M None None XRAY 2.9 0.21 0.257 A 331 310 0 0 0 0 [[712, 970]] 1.0 3ika TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2KA P00533 696 1020 1210.0 0UN:1101 Type1 Active DFGin 6.252 15.402 BLAminus -162.18, -166.94 57.57, 64.19 -89.05, 1.52 298.25, 111.15 -60.1, -40.29 in-in in 8.377 Saltbr-in 3.231 HRD-in -63.42, -47.14 78.88, -6.86 in-in-in SNCiii in-in ActLoopNT-in 2.731 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.48, 127.33 APE9-dihe-in -122.09, 137.71 APE8-dihe-in -92.31, 106.07 APE8-rot-na 35.16 APE67-dihe-in -60.76, -39.83 -65.9, -37.9 APE12-dist-na 13.719 APE11-dist-na 11.84 APE10-dist-na 11.783 APE9-dist-in 7.957 T790M None None XRAY 3.201 0.227 0.244 A 327 314 8 0 0 6 [[712, 970]] 1.0 5x2k TYR_EGFR_HUMAN TYR 8e-88 300.2 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYNA P00533 697 1018 1210.0 0UN:1101 Type1 Active DFGin 5.896 15.046 BLAminus -145.65, -166.89 58.05, 78.44 -95.11, 31.85 294.9, 83.85 -65.75, -30.64 in-in in 8.443 Saltbr-in 2.894 HRD-in -73.97, -47.38 70.32, 2.73 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.42, 134.47 APE9-dihe-in -142.75, 146.34 APE8-dihe-in -74.74, 108.36 APE8-rot-na 25.93 APE67-dihe-in -69.45, -12.52 -69.08, -37.0 APE12-dist-na 12.422 APE11-dist-na 9.178 APE10-dist-na 10.479 APE9-dist-in 6.554 T790M,C797S,E865A,E866A,K867A None None XRAY 2.3 0.193 0.223 A 333 317 4 0 0 0 [[712, 970]] 1.0 7zyn TYR_EGFR_HUMAN TYR 3.4e-87 298.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 0UN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 7ZYNA
DFGin ABAminus 1 33.3% 3IKAA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3IKAA P00533 696 1020 1210.0 0UN:1797 Type1 Inactive DFGin 5.778 14.354 ABAminus -126.08, -29.6 -103.63, 124.88 -119.83, 2.06 294.25, 104.41 -43.93, -35.44 in-in in 9.442 Saltbr-in 3.22 HRD-in -72.42, -49.2 76.65, -5.52 in-in-in SNCiii in-in ActLoopNT-in 2.91 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -121.67, 130.5 APE9-dihe-in -133.91, 150.07 APE8-dihe-in -89.48, 105.4 APE8-rot-na 32.64 APE67-dihe-in -62.96, -1.82 -70.92, -51.09 APE12-dist-na 11.082 APE11-dist-na 9.128 APE10-dist-na 9.94 APE9-dist-in 6.742 T790M None None XRAY 2.9 0.21 0.257 A 331 310 0 0 0 0 [[712, 970]] 1.0 3ika Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2KA P00533 696 1020 1210.0 0UN:1101 Type1 Active DFGin 6.252 15.402 BLAminus -162.18, -166.94 57.57, 64.19 -89.05, 1.52 298.25, 111.15 -60.1, -40.29 in-in in 8.377 Saltbr-in 3.231 HRD-in -63.42, -47.14 78.88, -6.86 in-in-in SNCiii in-in ActLoopNT-in 2.731 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.48, 127.33 APE9-dihe-in -122.09, 137.71 APE8-dihe-in -92.31, 106.07 APE8-rot-na 35.16 APE67-dihe-in -60.76, -39.83 -65.9, -37.9 APE12-dist-na 13.719 APE11-dist-na 11.84 APE10-dist-na 11.783 APE9-dist-in 7.957 T790M None None XRAY 3.201 0.227 0.244 A 327 314 8 0 0 6 [[712, 970]] 1.0 5x2k Homo sapiens TYR_EGFR_HUMAN TYR 8e-88 300.2 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYNA P00533 697 1018 1210.0 0UN:1101 Type1 Active DFGin 5.896 15.046 BLAminus -145.65, -166.89 58.05, 78.44 -95.11, 31.85 294.9, 83.85 -65.75, -30.64 in-in in 8.443 Saltbr-in 2.894 HRD-in -73.97, -47.38 70.32, 2.73 in-in-in SNCiii in-in ActLoopNT-in 2.899 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.42, 134.47 APE9-dihe-in -142.75, 146.34 APE8-dihe-in -74.74, 108.36 APE8-rot-na 25.93 APE67-dihe-in -69.45, -12.52 -69.08, -37.0 APE12-dist-na 12.422 APE11-dist-na 9.178 APE10-dist-na 10.479 APE9-dist-in 6.554 T790M,C797S,E865A,E866A,K867A None None XRAY 2.3 0.193 0.223 A 333 317 4 0 0 0 [[712, 970]] 1.0 7zyn Homo sapiens TYR_EGFR_HUMAN TYR 3.4e-87 298.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 0UN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name