Ligand: 0UJ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4FK6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4FK6A P23458 863 1154 1154.0 0UJ:1201 Type1 Inactive DFGin 6.5774 13.4134 ABAminus -112.19, 2.74 -147.97, 135.94 -128.79, 22.38 293.74, 90.76 -52.95, -29.36 in-in in 7.654 Saltbr-in 2.6738 HRD-in -73.71, -49.95 70.6, -2.02 in-in-out SNCiio in-out ActLoopNT-in 2.8101 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -107.7, 28.56 APE9-dihe-in -63.18, 134.95 APE8-dihe-in -78.74, 77.08 APE8-rot-na 27.11 APE67-dihe-in -76.1, -2.34 -51.26, -33.75 APE12-dist-na 11.3197 APE11-dist-na 12.8559 APE10-dist-na 10.101 APE9-dist-in 6.6455 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.211 0.251 A 302.0 287.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 4fk6 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4FK6B P23458 864 1154 1154.0 0UJ:1201 Type1 Inactive DFGin 6.5944 13.4059 ABAminus -112.12, 2.82 -147.85, 135.79 -128.94, 22.08 293.63, 90.77 -52.49, -30.06 in-in in 7.6382 Saltbr-in 2.6795 HRD-in -73.35, -50.23 70.8, -1.92 in-in-out SNCiio in-out ActLoopNT-in 2.8173 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.94, 28.16 APE9-dihe-in -62.61, 135.05 APE8-dihe-in -78.72, 77.07 APE8-rot-na 27.01 APE67-dihe-in -76.01, -2.17 -51.54, -33.82 APE12-dist-na 11.3135 APE11-dist-na 12.766 APE10-dist-na 10.1407 APE9-dist-in 6.6468 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.211 0.251 B 302.0 286.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 4fk6 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 0UJ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4FK6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4FK6A P23458 863 1154 1154.0 0UJ:1201 Type1 Inactive DFGin 6.5774 13.4134 ABAminus -112.19, 2.74 -147.97, 135.94 -128.79, 22.38 293.74, 90.76 -52.95, -29.36 in-in in 7.654 Saltbr-in 2.6738 HRD-in -73.71, -49.95 70.6, -2.02 in-in-out SNCiio in-out ActLoopNT-in 2.8101 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -107.7, 28.56 APE9-dihe-in -63.18, 134.95 APE8-dihe-in -78.74, 77.08 APE8-rot-na 27.11 APE67-dihe-in -76.1, -2.34 -51.26, -33.75 APE12-dist-na 11.3197 APE11-dist-na 12.8559 APE10-dist-na 10.101 APE9-dist-in 6.6455 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.211 0.251 A 302.0 287.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 4fk6 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4FK6B P23458 864 1154 1154.0 0UJ:1201 Type1 Inactive DFGin 6.5944 13.4059 ABAminus -112.12, 2.82 -147.85, 135.79 -128.94, 22.08 293.63, 90.77 -52.49, -30.06 in-in in 7.6382 Saltbr-in 2.6795 HRD-in -73.35, -50.23 70.8, -1.92 in-in-out SNCiio in-out ActLoopNT-in 2.8173 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.94, 28.16 APE9-dihe-in -62.61, 135.05 APE8-dihe-in -78.72, 77.07 APE8-rot-na 27.01 APE67-dihe-in -76.01, -2.17 -51.54, -33.82 APE12-dist-na 11.3135 APE11-dist-na 12.766 APE10-dist-na 10.1407 APE9-dist-in 6.6468 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.211 0.251 B 302.0 286.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 4fk6 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 0UJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name