Ligand: 0TP

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3TJCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3TJCA O60674 843 1132 1132.0 0TP:1 Type1 Inactive DFGin 6.1824 13.7756 ABAminus -111.28, 8.43 -150.47, 142.92 -136.09, 31.13 297.77, 93.1 -58.92, -26.75 in-in in 8.6326 Saltbr-in 2.701 HRD-in -58.35, -49.6 68.34, 2.22 in-in-in SNCiii in-in ActLoopNT-in 2.8072 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.05, 136.72 APE9-dihe-in -111.73, 151.95 APE8-dihe-in -78.69, 64.15 APE8-rot-na 33.68 APE67-dihe-in -82.41, 8.52 -50.91, -27.5 APE12-dist-na 12.8717 APE11-dist-na 12.6647 APE10-dist-na 13.0332 APE9-dist-in 7.847 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.265 0.275 A 298.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjc TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJCB O60674 840 1132 1132.0 0TP:1 Type1 Inactive DFGin 6.3827 14.1256 ABAminus -116.85, 12.84 -151.32, 140.31 -135.01, 33.47 291.72, 91.04 -63.92, -25.01 in-in in 8.4687 Saltbr-in 2.7607 HRD-in -67.53, -45.4 67.54, -5.76 in-in-in SNCiii in-in ActLoopNT-in 2.7258 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.38, 138.96 APE9-dihe-in -114.25, 144.01 APE8-dihe-in -76.43, 71.46 APE8-rot-na 32.78 APE67-dihe-in -82.33, 3.33 -53.44, -26.31 APE12-dist-na 12.4636 APE11-dist-na 10.8267 APE10-dist-na 12.4103 APE9-dist-in 7.632 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.265 0.275 B 298.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjc TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: 0TP

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3TJCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3TJCA O60674 843 1132 1132.0 0TP:1 Type1 Inactive DFGin 6.1824 13.7756 ABAminus -111.28, 8.43 -150.47, 142.92 -136.09, 31.13 297.77, 93.1 -58.92, -26.75 in-in in 8.6326 Saltbr-in 2.701 HRD-in -58.35, -49.6 68.34, 2.22 in-in-in SNCiii in-in ActLoopNT-in 2.8072 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.05, 136.72 APE9-dihe-in -111.73, 151.95 APE8-dihe-in -78.69, 64.15 APE8-rot-na 33.68 APE67-dihe-in -82.41, 8.52 -50.91, -27.5 APE12-dist-na 12.8717 APE11-dist-na 12.6647 APE10-dist-na 13.0332 APE9-dist-in 7.847 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.265 0.275 A 298.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjc Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJCB O60674 840 1132 1132.0 0TP:1 Type1 Inactive DFGin 6.3827 14.1256 ABAminus -116.85, 12.84 -151.32, 140.31 -135.01, 33.47 291.72, 91.04 -63.92, -25.01 in-in in 8.4687 Saltbr-in 2.7607 HRD-in -67.53, -45.4 67.54, -5.76 in-in-in SNCiii in-in ActLoopNT-in 2.7258 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.38, 138.96 APE9-dihe-in -114.25, 144.01 APE8-dihe-in -76.43, 71.46 APE8-rot-na 32.78 APE67-dihe-in -82.33, 3.33 -53.44, -26.31 APE12-dist-na 12.4636 APE11-dist-na 10.8267 APE10-dist-na 12.4103 APE9-dist-in 7.632 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.265 0.275 B 298.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3tjc Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: 0TP

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name