Ligand: 0S8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 4F64A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 4F64A P11362 464 762 822.0 0S8:801 Type1 Inactive DFGin 5.183 13.118 BLAplus -126.63, 159.8 67.66, 19.43 -73.38, -15.37 61.14, 82.05 -112.05, 14.31 in-in in 7.833 Saltbr-in 2.657 HRD-in -75.01, -53.26 79.37, -13.8 in-out-out SNCioo out-out ActLoopNT-out 8.889 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -105.36, 162.32 APE9-dihe-in -110.59, 112.62 APE8-dihe-out -54.21, -21.82 APE8-rot-na 334.94 APE67-dihe-in -73.68, -4.51 -58.01, -22.74 APE12-dist-na 19.925 APE11-dist-na 21.624 APE10-dist-na 19.607 APE9-dist-out 11.74 C488A,C584S None None XRAY 2.05 0.217 0.269 A 309 278 21 0 0 0 [[478, 756]] 1.0 4f64 TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F64B P11362 461 761 822.0 0S8:801 Type1 Inactive DFGin 5.167 12.905 BLAplus -128.73, 164.19 64.4, 29.6 -84.21, -15.05 59.33, 82.94 -106.3, 1.28 in-in in 7.894 Saltbr-in 2.864 HRD-in -73.33, -50.22 71.98, 0.27 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -113.2, 170.72 APE9-dihe-in -106.18, 108.15 APE8-dihe-out -52.36, -27.43 APE8-rot-na 328.0 APE67-dihe-in -80.92, -6.4 -55.61, -16.72 APE12-dist-na 999.0 APE11-dist-na 20.995 APE10-dist-na 19.853 APE9-dist-out 11.556 C488A,C584S None None XRAY 2.05 0.217 0.269 B 309 272 29 0 0 9 [[478, 756]] 1.0 4f64 TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

Ligand: 0S8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 4F64A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 4F64A P11362 464 762 822.0 0S8:801 Type1 Inactive DFGin 5.183 13.118 BLAplus -126.63, 159.8 67.66, 19.43 -73.38, -15.37 61.14, 82.05 -112.05, 14.31 in-in in 7.833 Saltbr-in 2.657 HRD-in -75.01, -53.26 79.37, -13.8 in-out-out SNCioo out-out ActLoopNT-out 8.889 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -105.36, 162.32 APE9-dihe-in -110.59, 112.62 APE8-dihe-out -54.21, -21.82 APE8-rot-na 334.94 APE67-dihe-in -73.68, -4.51 -58.01, -22.74 APE12-dist-na 19.925 APE11-dist-na 21.624 APE10-dist-na 19.607 APE9-dist-out 11.74 C488A,C584S None None XRAY 2.05 0.217 0.269 A 309 278 21 0 0 0 [[478, 756]] 1.0 4f64 Homo sapiens TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F64B P11362 461 761 822.0 0S8:801 Type1 Inactive DFGin 5.167 12.905 BLAplus -128.73, 164.19 64.4, 29.6 -84.21, -15.05 59.33, 82.94 -106.3, 1.28 in-in in 7.894 Saltbr-in 2.864 HRD-in -73.33, -50.22 71.98, 0.27 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -113.2, 170.72 APE9-dihe-in -106.18, 108.15 APE8-dihe-out -52.36, -27.43 APE8-rot-na 328.0 APE67-dihe-in -80.92, -6.4 -55.61, -16.72 APE12-dist-na 999.0 APE11-dist-na 20.995 APE10-dist-na 19.853 APE9-dist-out 11.556 C488A,C584S None None XRAY 2.05 0.217 0.269 B 309 272 29 0 0 9 [[478, 756]] 1.0 4f64 Homo sapiens TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

Ligand: 0S8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name