Ligand: 0NU

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E6DA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4E6DA O60674 840 1132 1132.0 0NU:1201 Type1 Inactive DFGin 6.0961 13.3116 ABAminus -122.24, 3.75 -153.98, 144.84 -134.34, 24.14 296.82, 81.89 -55.12, -26.57 in-in in 8.2475 Saltbr-in 2.6491 HRD-in -69.92, -47.82 71.55, -0.63 in-in-in SNCiii in-in ActLoopNT-in 2.6854 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -112.79, 131.23 APE9-dihe-in -111.58, 150.84 APE8-dihe-in -76.94, 65.01 APE8-rot-na 34.92 APE67-dihe-in -79.16, -3.09 -56.44, -27.07 APE12-dist-na 12.5057 APE11-dist-na 13.314 APE10-dist-na 12.7745 APE9-dist-in 7.9674 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.22 0.162 0.203 A 298.0 288.0 5 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6d TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6DB O60674 840 1132 1132.0 0NU:1201 Type1 Inactive DFGin 6.3056 13.3866 ABAminus -117.06, 8.14 -158.35, 146.27 -137.86, 24.42 294.7, 80.09 -57.56, -27.02 in-in in 8.175 Saltbr-in 2.7206 HRD-in -78.46, -40.84 73.08, -9.79 in-in-in SNCiii in-in ActLoopNT-in 2.7958 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.69, 149.18 APE9-dihe-in -123.01, 137.44 APE8-dihe-in -75.9, 62.49 APE8-rot-na 355.6 APE67-dihe-in -81.97, -0.11 -52.79, -31.49 APE12-dist-na 7.2504 APE11-dist-na 9.8819 APE10-dist-na 11.5794 APE9-dist-in 7.6521 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.22 0.162 0.203 B 298.0 288.0 5 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6d TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: 0NU

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E6DA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4E6DA O60674 840 1132 1132.0 0NU:1201 Type1 Inactive DFGin 6.0961 13.3116 ABAminus -122.24, 3.75 -153.98, 144.84 -134.34, 24.14 296.82, 81.89 -55.12, -26.57 in-in in 8.2475 Saltbr-in 2.6491 HRD-in -69.92, -47.82 71.55, -0.63 in-in-in SNCiii in-in ActLoopNT-in 2.6854 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -112.79, 131.23 APE9-dihe-in -111.58, 150.84 APE8-dihe-in -76.94, 65.01 APE8-rot-na 34.92 APE67-dihe-in -79.16, -3.09 -56.44, -27.07 APE12-dist-na 12.5057 APE11-dist-na 13.314 APE10-dist-na 12.7745 APE9-dist-in 7.9674 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.22 0.162 0.203 A 298.0 288.0 5 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6d Homo sapiens TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6DB O60674 840 1132 1132.0 0NU:1201 Type1 Inactive DFGin 6.3056 13.3866 ABAminus -117.06, 8.14 -158.35, 146.27 -137.86, 24.42 294.7, 80.09 -57.56, -27.02 in-in in 8.175 Saltbr-in 2.7206 HRD-in -78.46, -40.84 73.08, -9.79 in-in-in SNCiii in-in ActLoopNT-in 2.7958 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.69, 149.18 APE9-dihe-in -123.01, 137.44 APE8-dihe-in -75.9, 62.49 APE8-rot-na 355.6 APE67-dihe-in -81.97, -0.11 -52.79, -31.49 APE12-dist-na 7.2504 APE11-dist-na 9.8819 APE10-dist-na 11.5794 APE9-dist-in 7.6521 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.22 0.162 0.203 B 298.0 288.0 5 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6d Homo sapiens TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: 0NU

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name