Ligand: 0NT

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E5WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4E5WA P23458 854 1154 1154.0 0NT:61201 Type1 Inactive DFGin 6.562 13.397 ABAminus -118.14, 5.18 -153.89, 137.32 -129.51, 26.76 295.21, 88.69 -58.94, -26.21 in-in in 7.7041 Saltbr-in 2.6868 HRD-in -73.36, -50.75 70.96, 2.6 in-in-out SNCiio in-out ActLoopNT-in 2.8337 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.84, 26.34 APE9-dihe-in -57.31, 135.68 APE8-dihe-in -78.98, 72.49 APE8-rot-na 27.03 APE67-dihe-in -72.09, -3.1 -47.71, -39.24 APE12-dist-na 11.0884 APE11-dist-na 13.5699 APE10-dist-na 10.4497 APE9-dist-in 6.7378 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.86 0.184 0.21 A 302.0 293.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4e5w TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E5WB P23458 865 1153 1154.0 0NT:61202 Type1 Inactive DFGin 6.5301 13.3501 ABAminus -114.8, 7.46 -153.87, 137.96 -129.8, 26.64 296.41, 93.24 -58.91, -27.51 in-in in 7.6911 Saltbr-in 2.6865 HRD-in -74.04, -50.94 71.65, 3.46 in-in-out SNCiio in-out ActLoopNT-in 2.8325 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.41, 26.14 APE9-dihe-in -57.59, 134.48 APE8-dihe-in -78.71, 72.64 APE8-rot-na 26.79 APE67-dihe-in -72.94, -2.19 -48.23, -38.49 APE12-dist-na 11.1134 APE11-dist-na 13.5566 APE10-dist-na 10.4312 APE9-dist-in 6.7576 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.86 0.184 0.21 B 302.0 280.0 9 31 29 2 [[583, 847], [875, 1151]] 2.0 4e5w TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 0NT

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E5WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4E5WA P23458 854 1154 1154.0 0NT:61201 Type1 Inactive DFGin 6.562 13.397 ABAminus -118.14, 5.18 -153.89, 137.32 -129.51, 26.76 295.21, 88.69 -58.94, -26.21 in-in in 7.7041 Saltbr-in 2.6868 HRD-in -73.36, -50.75 70.96, 2.6 in-in-out SNCiio in-out ActLoopNT-in 2.8337 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.84, 26.34 APE9-dihe-in -57.31, 135.68 APE8-dihe-in -78.98, 72.49 APE8-rot-na 27.03 APE67-dihe-in -72.09, -3.1 -47.71, -39.24 APE12-dist-na 11.0884 APE11-dist-na 13.5699 APE10-dist-na 10.4497 APE9-dist-in 6.7378 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.86 0.184 0.21 A 302.0 293.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4e5w Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E5WB P23458 865 1153 1154.0 0NT:61202 Type1 Inactive DFGin 6.5301 13.3501 ABAminus -114.8, 7.46 -153.87, 137.96 -129.8, 26.64 296.41, 93.24 -58.91, -27.51 in-in in 7.6911 Saltbr-in 2.6865 HRD-in -74.04, -50.94 71.65, 3.46 in-in-out SNCiio in-out ActLoopNT-in 2.8325 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.41, 26.14 APE9-dihe-in -57.59, 134.48 APE8-dihe-in -78.71, 72.64 APE8-rot-na 26.79 APE67-dihe-in -72.94, -2.19 -48.23, -38.49 APE12-dist-na 11.1134 APE11-dist-na 13.5566 APE10-dist-na 10.4312 APE9-dist-in 6.7576 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.86 0.184 0.21 B 302.0 280.0 9 31 29 2 [[583, 847], [875, 1151]] 2.0 4e5w Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 0NT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name