Ligand: 0NL

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E4NB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4E4NA P23458 854 1154 1154.0 0NL:61201 Type1 Inactive DFGin 6.3841 13.5599 ABAminus -120.02, 11.21 -158.48, 139.99 -136.43, 26.78 297.09, 85.57 -63.39, -21.4 in-in in 7.7905 Saltbr-in 2.5546 HRD-in -80.31, -49.85 72.5, 4.9 in-in-out SNCiio in-out ActLoopNT-in 2.8478 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -96.76, 48.8 APE9-dihe-in -75.99, 139.57 APE8-dihe-in -78.93, 73.17 APE8-rot-na 33.7 APE67-dihe-in -74.47, -3.41 -60.94, -30.72 APE12-dist-na 11.0707 APE11-dist-na 12.7564 APE10-dist-na 10.411 APE9-dist-in 6.8318 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.226 A 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4e4n TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4NB P23458 865 1154 1154.0 0NL:61201 Type1 Inactive DFGin 6.3464 13.5023 ABAminus -119.9, 9.63 -155.68, 139.61 -133.8, 28.11 297.19, 80.43 -62.66, -24.74 in-in in 7.7373 Saltbr-in 2.6034 HRD-in -78.32, -48.47 74.25, 0.38 in-in-out SNCiio in-out ActLoopNT-in 2.8745 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -107.54, 49.17 APE9-dihe-in -76.21, 142.06 APE8-dihe-in -79.22, 71.62 APE8-rot-na 25.59 APE67-dihe-in -77.0, -5.97 -60.76, -27.4 APE12-dist-na 11.1624 APE11-dist-na 12.7927 APE10-dist-na 10.4333 APE9-dist-in 6.9387 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.226 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4e4n TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 0NL

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E4NB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4E4NA P23458 854 1154 1154.0 0NL:61201 Type1 Inactive DFGin 6.3841 13.5599 ABAminus -120.02, 11.21 -158.48, 139.99 -136.43, 26.78 297.09, 85.57 -63.39, -21.4 in-in in 7.7905 Saltbr-in 2.5546 HRD-in -80.31, -49.85 72.5, 4.9 in-in-out SNCiio in-out ActLoopNT-in 2.8478 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -96.76, 48.8 APE9-dihe-in -75.99, 139.57 APE8-dihe-in -78.93, 73.17 APE8-rot-na 33.7 APE67-dihe-in -74.47, -3.41 -60.94, -30.72 APE12-dist-na 11.0707 APE11-dist-na 12.7564 APE10-dist-na 10.411 APE9-dist-in 6.8318 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.226 A 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4e4n Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4NB P23458 865 1154 1154.0 0NL:61201 Type1 Inactive DFGin 6.3464 13.5023 ABAminus -119.9, 9.63 -155.68, 139.61 -133.8, 28.11 297.19, 80.43 -62.66, -24.74 in-in in 7.7373 Saltbr-in 2.6034 HRD-in -78.32, -48.47 74.25, 0.38 in-in-out SNCiio in-out ActLoopNT-in 2.8745 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -107.54, 49.17 APE9-dihe-in -76.21, 142.06 APE8-dihe-in -79.22, 71.62 APE8-rot-na 25.59 APE67-dihe-in -77.0, -5.97 -60.76, -27.4 APE12-dist-na 11.1624 APE11-dist-na 12.7927 APE10-dist-na 10.4333 APE9-dist-in 6.9387 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.226 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4e4n Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: 0NL

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name