Ligand: 02A

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S76B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S76A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,02A:509,02A:510 Type1,Allosteric,Allosteric,Allosteric,Type1.5_Back Inactive DFGin 8.3968 13.3521 BLAminus -125.71, 163.24 76.56, 90.11 -103.29, 26.3 299.59, 179.12 -70.47, -16.36 in-out in 9.1694 Saltbr-out 6.1364 HRD-in -78.12, -53.94 78.79, 0.3 out-in-out SNCoio in-out ActLoopNT-in 2.9104 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -121.64, 170.51 APE9-dihe-na -62.2, 167.24 APE8-dihe-in -63.35, 123.08 APE8-rot-in 302.24 APE67-dihe-in -58.65, -29.05 -63.37, -35.67 APE12-dist-none 999.0 APE11-dist-out 6.2237 APE10-dist-out 8.9115 APE9-dist-in 3.6733 Q207D None None XRAY 1.31 0.156 0.173 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s76 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S76B Q04771 205 499 509.0 LU8:501,02A:505 Type1,Type1.5_Back Inactive DFGin 7.0455 13.388 BLAminus -126.37, 161.8 77.8, 87.16 -99.2, 20.64 303.2, 173.97 -68.3, -17.34 in-out in 8.8877 Saltbr-out 4.7352 HRD-in -77.8, -54.12 78.31, -2.4 out-in-out SNCoio in-out ActLoopNT-in 2.9422 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.39, 162.33 APE9-dihe-na -57.18, 164.84 APE8-dihe-in -61.8, 127.01 APE8-rot-in 299.22 APE67-dihe-in -57.98, -30.25 -60.93, -39.7 APE12-dist-in 10.3885 APE11-dist-out 6.1918 APE10-dist-out 9.0776 APE9-dist-in 3.7583 Q207D None None XRAY 1.31 0.156 0.173 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s76 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: 02A

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S76B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S76A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,02A:509,02A:510 Type1,Allosteric,Allosteric,Allosteric,Type1.5_Back Inactive DFGin 8.3968 13.3521 BLAminus -125.71, 163.24 76.56, 90.11 -103.29, 26.3 299.59, 179.12 -70.47, -16.36 in-out in 9.1694 Saltbr-out 6.1364 HRD-in -78.12, -53.94 78.79, 0.3 out-in-out SNCoio in-out ActLoopNT-in 2.9104 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -121.64, 170.51 APE9-dihe-na -62.2, 167.24 APE8-dihe-in -63.35, 123.08 APE8-rot-in 302.24 APE67-dihe-in -58.65, -29.05 -63.37, -35.67 APE12-dist-none 999.0 APE11-dist-out 6.2237 APE10-dist-out 8.9115 APE9-dist-in 3.6733 Q207D None None XRAY 1.31 0.156 0.173 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s76 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S76B Q04771 205 499 509.0 LU8:501,02A:505 Type1,Type1.5_Back Inactive DFGin 7.0455 13.388 BLAminus -126.37, 161.8 77.8, 87.16 -99.2, 20.64 303.2, 173.97 -68.3, -17.34 in-out in 8.8877 Saltbr-out 4.7352 HRD-in -77.8, -54.12 78.31, -2.4 out-in-out SNCoio in-out ActLoopNT-in 2.9422 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.39, 162.33 APE9-dihe-na -57.18, 164.84 APE8-dihe-in -61.8, 127.01 APE8-rot-in 299.22 APE67-dihe-in -57.98, -30.25 -60.93, -39.7 APE12-dist-in 10.3885 APE11-dist-out 6.1918 APE10-dist-out 9.0776 APE9-dist-in 3.7583 Q207D None None XRAY 1.31 0.156 0.173 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s76 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: 02A

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name