OTHER_WNK2 (Serine/threonine-protein kinase WNK2)

Total number of chains: 2
Active chains: 2
Uniprot: WNK2_HUMAN
Kinase Domain Residues: 194 - 453
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9Y3S1-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
WNK2 AF-Q9Y3S1-K1A Q9Y3S1 186 461 2297.0 No_ligand No_ligand Active DFGin 6.9336 12.3757 BLAminus -120.89, -161.02 57.35, 44.89 -67.15, 8.11 303.91, 176.5 -66.03, -16.82 out-na out 15.199 Saltbr-na 999.0 HRD-in -71.35, -44.99 64.44, -5.7 na-in-in SNCaii in-in ActLoopNT-in 2.9739 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.09, 149.05 APE9-dihe-na 142.14, -175.6 APE8-dihe-in -86.55, 118.64 APE8-rot-in 302.02 APE67-dihe-in -64.28, -20.73 -50.95, -36.03 APE12-dist-in 8.5702 APE11-dist-in 12.029 APE10-dist-in 6.3493 APE9-dist-in 3.5489 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[194, 453]] 1.0 AF-Q9Y3S1-K1 OTHER_WNK2_HUMAN WNK 2.4e-177 593.4 1.0 260.0 260.0 341 342 343 345 347 224 242 246 320 322 321 323.0 378 367 362 361 360 359 358 357 356 276 Serine/threonine-protein kinase WNK2
WNK2 AF-Q9Y3S1-K3A Q9Y3S1 186 461 2297.0 No_ligand No_ligand Active DFGin 6.7026 13.0097 BLAminus -128.69, -164.36 56.84, 43.1 -64.95, 8.5 305.03, 177.08 -67.2, -13.34 out-na out 14.3285 Saltbr-na 999.0 HRD-in -72.6, -42.44 63.46, -9.88 na-in-in SNCaii in-in ActLoopNT-in 2.8961 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.9, 136.91 APE9-dihe-na 150.13, -174.05 APE8-dihe-in -92.56, 119.06 APE8-rot-in 299.06 APE67-dihe-in -68.79, -16.43 -51.43, -35.59 APE12-dist-in 9.1265 APE11-dist-in 12.2078 APE10-dist-in 6.5914 APE9-dist-in 3.5198 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[194, 453]] 1.0 AF-Q9Y3S1-K3 OTHER_WNK2_HUMAN WNK 2.4e-177 593.4 1.0 260.0 260.0 341 342 343 345 347 224 242 246 320 322 321 323.0 378 367 362 361 360 359 358 357 356 276 Serine/threonine-protein kinase WNK2

OTHER_WNK2 (Serine/threonine-protein kinase WNK2)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9Y3S1-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
WNK2 WNK2_HUMAN AF-Q9Y3S1-K1A Q9Y3S1 186 461 2297.0 No_ligand No_ligand Active DFGin 6.9336 12.3757 BLAminus -120.89, -161.02 57.35, 44.89 -67.15, 8.11 303.91, 176.5 -66.03, -16.82 out-na out 15.199 Saltbr-na 999.0 HRD-in -71.35, -44.99 64.44, -5.7 na-in-in SNCaii in-in ActLoopNT-in 2.9739 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.09, 149.05 APE9-dihe-na 142.14, -175.6 APE8-dihe-in -86.55, 118.64 APE8-rot-in 302.02 APE67-dihe-in -64.28, -20.73 -50.95, -36.03 APE12-dist-in 8.5702 APE11-dist-in 12.029 APE10-dist-in 6.3493 APE9-dist-in 3.5489 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[194, 453]] 1.0 AF-Q9Y3S1-K1 Homo sapiens OTHER_WNK2_HUMAN WNK 2.4e-177 593.4 1.0 260.0 260.0 341 342 343 345 347 224 242 246 320 322 321 323.0 378 367 362 361 360 359 358 357 356 276 Serine/threonine-protein kinase WNK2
WNK2 WNK2_HUMAN AF-Q9Y3S1-K3A Q9Y3S1 186 461 2297.0 No_ligand No_ligand Active DFGin 6.7026 13.0097 BLAminus -128.69, -164.36 56.84, 43.1 -64.95, 8.5 305.03, 177.08 -67.2, -13.34 out-na out 14.3285 Saltbr-na 999.0 HRD-in -72.6, -42.44 63.46, -9.88 na-in-in SNCaii in-in ActLoopNT-in 2.8961 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.9, 136.91 APE9-dihe-na 150.13, -174.05 APE8-dihe-in -92.56, 119.06 APE8-rot-in 299.06 APE67-dihe-in -68.79, -16.43 -51.43, -35.59 APE12-dist-in 9.1265 APE11-dist-in 12.2078 APE10-dist-in 6.5914 APE9-dist-in 3.5198 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 26 26 0 [[194, 453]] 1.0 AF-Q9Y3S1-K3 Homo sapiens OTHER_WNK2_HUMAN WNK 2.4e-177 593.4 1.0 260.0 260.0 341 342 343 345 347 224 242 246 320 322 321 323.0 378 367 362 361 360 359 358 357 356 276 Serine/threonine-protein kinase WNK2

OTHER_WNK2 (Serine/threonine-protein kinase WNK2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name