OTHER_WEE2 (Wee1-like protein kinase 2)

Total number of chains: 3
Active chains: 1
Uniprot: WEE2_HUMAN
Kinase Domain Residues: 212 - 486
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-P0C1S8-K3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
WEE2 AF-P0C1S8-K3A P0C1S8 204 494 567.0 No_ligand No_ligand Active DFGin 4.8938 12.4972 BLAminus -119.45, -168.98 52.61, 59.95 -76.18, 12.61 302.76, 173.67 -62.64, -30.65 in-in in 8.5768 Saltbr-in 2.6765 HRD-in -81.7, -40.04 64.39, -17.02 in-in-in SNCiii in-in ActLoopNT-in 2.836 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -105.49, 9.11 APE9-dihe-na -67.07, 172.0 APE8-dihe-in -63.15, 114.72 APE8-rot-na 187.96 APE67-dihe-in -76.52, -29.76 -55.98, -20.19 APE12-dist-in 7.8901 APE11-dist-in 12.0388 APE10-dist-in 7.9724 APE9-dist-in 4.4399 None None None AF2 -1.0 1.0 1.0 A 291.0 291.0 0 24 24 0 [[72, 512]] 1.0 AF-P0C1S8-K3 OTHER_WEE2_HUMAN NEK 8.8e-28 133.4 4.0 139.0 258.0 379 380 381 383 385 241 259 263 336 338 337 339.0 416 403 398 397 396 395 394 393 392 290 Wee1-like protein kinase 2
WEE2 AF-P0C1S8-K1A P0C1S8 204 494 567.0 No_ligand No_ligand Inactive DFGin 5.3196 12.4321 BLAminus -134.3, -173.99 56.51, 72.13 -83.29, 17.15 299.06, 178.27 -58.97, -32.71 in-in in 8.3709 Saltbr-in 2.7592 HRD-in -86.34, -43.98 65.43, -12.21 in-in-out SNCiio in-out ActLoopNT-in 2.9244 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_iooi APE10-dihe-na -60.93, 117.49 APE9-dihe-na -76.85, -151.62 APE8-dihe-in -67.85, 108.91 APE8-rot-na 189.25 APE67-dihe-in -65.75, -31.9 -51.0, -20.9 APE12-dist-in 8.1221 APE11-dist-out 5.3634 APE10-dist-out 9.271 APE9-dist-in 4.5454 None None None AF2 -1.0 1.0 1.0 A 291.0 291.0 0 24 24 0 [[72, 512]] 1.0 AF-P0C1S8-K1 OTHER_WEE2_HUMAN NEK 8.8e-28 133.4 4.0 139.0 258.0 379 380 381 383 385 241 259 263 336 338 337 339.0 416 403 398 397 396 395 394 393 392 290 Wee1-like protein kinase 2
WEE2 5VDKA P0C1S8 204 486 567.0 8X7:501 Type1 Inactive DFGin 6.4749 12.7642 BLAminus -132.14, -176.96 59.49, 97.22 -108.31, 27.61 318.48, 177.21 -67.75, -13.32 in-in in 8.8786 Saltbr-in 2.3427 HRD-in -78.19, -59.39 74.05, 21.2 in-in-out SNCiio in-out ActLoopNT-in 3.0583 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_iooi APE10-dihe-na -64.06, 140.87 APE9-dihe-na -77.49, -156.13 APE8-dihe-in -55.32, 132.04 APE8-rot-na 187.37 APE67-dihe-in -66.18, -15.37 -69.73, -32.22 APE12-dist-in 8.3338 APE11-dist-out 5.9297 APE10-dist-out 8.8777 APE9-dist-in 3.4176 None None None XRAY 2.7 0.228 0.284 A 297.0 260.0 23 24 24 0 [[72, 512]] 1.0 5vdk OTHER_WEE2_HUMAN NEK 9.3e-28 133.3 4.0 139.0 258.0 379 380 381 383 385 241 259 263 336 338 337 339.0 416 403 398 397 396 395 394 393 392 290 Wee1-like protein kinase 2

OTHER_WEE2 (Wee1-like protein kinase 2)

Total number of chains: 3
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-P0C1S8-K3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
WEE2 WEE2_HUMAN AF-P0C1S8-K3A P0C1S8 204 494 567.0 No_ligand No_ligand Active DFGin 4.8938 12.4972 BLAminus -119.45, -168.98 52.61, 59.95 -76.18, 12.61 302.76, 173.67 -62.64, -30.65 in-in in 8.5768 Saltbr-in 2.6765 HRD-in -81.7, -40.04 64.39, -17.02 in-in-in SNCiii in-in ActLoopNT-in 2.836 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -105.49, 9.11 APE9-dihe-na -67.07, 172.0 APE8-dihe-in -63.15, 114.72 APE8-rot-na 187.96 APE67-dihe-in -76.52, -29.76 -55.98, -20.19 APE12-dist-in 7.8901 APE11-dist-in 12.0388 APE10-dist-in 7.9724 APE9-dist-in 4.4399 None None None AF2 -1.0 1.0 1.0 A 291.0 291.0 0 24 24 0 [[72, 512]] 1.0 AF-P0C1S8-K3 Homo sapiens OTHER_WEE2_HUMAN NEK 8.8e-28 133.4 4.0 139.0 258.0 379 380 381 383 385 241 259 263 336 338 337 339.0 416 403 398 397 396 395 394 393 392 290 Wee1-like protein kinase 2
WEE2 WEE2_HUMAN AF-P0C1S8-K1A P0C1S8 204 494 567.0 No_ligand No_ligand Inactive DFGin 5.3196 12.4321 BLAminus -134.3, -173.99 56.51, 72.13 -83.29, 17.15 299.06, 178.27 -58.97, -32.71 in-in in 8.3709 Saltbr-in 2.7592 HRD-in -86.34, -43.98 65.43, -12.21 in-in-out SNCiio in-out ActLoopNT-in 2.9244 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_iooi APE10-dihe-na -60.93, 117.49 APE9-dihe-na -76.85, -151.62 APE8-dihe-in -67.85, 108.91 APE8-rot-na 189.25 APE67-dihe-in -65.75, -31.9 -51.0, -20.9 APE12-dist-in 8.1221 APE11-dist-out 5.3634 APE10-dist-out 9.271 APE9-dist-in 4.5454 None None None AF2 -1.0 1.0 1.0 A 291.0 291.0 0 24 24 0 [[72, 512]] 1.0 AF-P0C1S8-K1 Homo sapiens OTHER_WEE2_HUMAN NEK 8.8e-28 133.4 4.0 139.0 258.0 379 380 381 383 385 241 259 263 336 338 337 339.0 416 403 398 397 396 395 394 393 392 290 Wee1-like protein kinase 2
WEE2 WEE2_HUMAN 5VDKA P0C1S8 204 486 567.0 8X7:501 Type1 Inactive DFGin 6.4749 12.7642 BLAminus -132.14, -176.96 59.49, 97.22 -108.31, 27.61 318.48, 177.21 -67.75, -13.32 in-in in 8.8786 Saltbr-in 2.3427 HRD-in -78.19, -59.39 74.05, 21.2 in-in-out SNCiio in-out ActLoopNT-in 3.0583 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_iooi APE10-dihe-na -64.06, 140.87 APE9-dihe-na -77.49, -156.13 APE8-dihe-in -55.32, 132.04 APE8-rot-na 187.37 APE67-dihe-in -66.18, -15.37 -69.73, -32.22 APE12-dist-in 8.3338 APE11-dist-out 5.9297 APE10-dist-out 8.8777 APE9-dist-in 3.4176 None None None XRAY 2.7 0.228 0.284 A 297.0 260.0 23 24 24 0 [[72, 512]] 1.0 5vdk Homo sapiens OTHER_WEE2_HUMAN NEK 9.3e-28 133.3 4.0 139.0 258.0 379 380 381 383 385 241 259 263 336 338 337 339.0 416 403 398 397 396 395 394 393 392 290 Wee1-like protein kinase 2

OTHER_WEE2 (Wee1-like protein kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name