KinCore

CAMK_TRIB2 (Tribbles homolog 2)

Total number of chains: 1

Active chains: 0

Uniprot: TRIB2_HUMAN

Kinase Domain Residues: 64 - 308

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	ABAminus	1	100.0%	7UPMA

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Gene	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
TRIB2	7UPMA	Q92519	55	312	343.0	No_ligand	No_ligand	Pseudo	DFGin	4.9053	14.4403	ABAminus	-58.01, -48.87	-164.7, 172.09	-114.04, 14.33	303.11, 167.65	-48.53, -44.56	in-na	in	9.5876	Saltbr-na	999.0	HRD-in	-81.23, -42.97	77.99, -33.0	na-in-out	SNCaio	in-out	ActLoopNT-in	2.8738	ActLoopCT-out	nonTYR	APEdihe_aaiai	APEdist_iooi	APE10-dihe-na	-129.77, 155.01	APE9-dihe-na	130.76, 152.14	APE8-dihe-in	-71.56, 130.0	APE8-rot-na	194.78	APE67-dihe-in	-65.79, -28.93	-44.49, -39.77	APE12-dist-in	12.6199	APE11-dist-out	15.2789	APE10-dist-out	9.7337	APE9-dist-in	3.7272	None	None	None	XRAY	2.7	0.207	0.26	A	264.0	258.0	0	28	28	0	[[64, 308]]	1.0	7upm	CAMK_TRIB2_HUMAN	CAMK	2.3e-61	213.3	14.0	256.0	243.0	194	195	196	198	200	90	100	104	172	174	173	175.0	236	222	217	216	215	214	213	212	211	131	Tribbles homolog 2

CAMK_TRIB2 (Tribbles homolog 2)

Total number of chains: 1

Active chains: 0

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	ABAminus	1	100.0%	7UPMA

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Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
TRIB2	TRIB2_HUMAN	7UPMA	Q92519	55	312	343.0	No_ligand	No_ligand	Pseudo	DFGin	4.9053	14.4403	ABAminus	-58.01, -48.87	-164.7, 172.09	-114.04, 14.33	303.11, 167.65	-48.53, -44.56	in-na	in	9.5876	Saltbr-na	999.0	HRD-in	-81.23, -42.97	77.99, -33.0	na-in-out	SNCaio	in-out	ActLoopNT-in	2.8738	ActLoopCT-out	nonTYR	APEdihe_aaiai	APEdist_iooi	APE10-dihe-na	-129.77, 155.01	APE9-dihe-na	130.76, 152.14	APE8-dihe-in	-71.56, 130.0	APE8-rot-na	194.78	APE67-dihe-in	-65.79, -28.93	-44.49, -39.77	APE12-dist-in	12.6199	APE11-dist-out	15.2789	APE10-dist-out	9.7337	APE9-dist-in	3.7272	None	None	None	XRAY	2.7	0.207	0.26	A	264.0	258.0	0	28	28	0	[[64, 308]]	1.0	7upm	Homo sapiens	CAMK_TRIB2_HUMAN	CAMK	2.3e-61	213.3	14.0	256.0	243.0	194	195	196	198	200	90	100	104	172	174	173	175.0	236	222	217	216	215	214	213	212	211	131	Tribbles homolog 2

CAMK_TRIB2 (Tribbles homolog 2)

Total number of chains: 0

Active chains: 0

Spatial label	Dihedral label	Number of Chains	Percent	Representative

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Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name