AGC_RPS6KA4-1 (Ribosomal protein S6 kinase alpha-4)

Total number of chains: 2
Active chains: 2
Uniprot: KS6A4_HUMAN
Kinase Domain Residues: 33 - 301
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O75676-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA4-1 AF-O75676-K1A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 6.5976 13.7105 BLAminus -124.98, -168.39 42.55, 70.55 -80.59, 14.7 297.97, 83.91 -61.19, -20.29 in-in in 8.7699 Saltbr-in 2.6042 HRD-in -82.76, -47.29 63.76, 4.18 in-in-in SNCiii in-in ActLoopNT-in 2.9195 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.03, 161.17 APE9-dihe-na 111.84, 169.32 APE8-dihe-in -72.29, 131.49 APE8-rot-in 292.11 APE67-dihe-in -60.98, -29.84 -59.69, -36.55 APE12-dist-in 8.5409 APE11-dist-in 11.5169 APE10-dist-in 5.7607 APE9-dist-in 3.5937 None None None AF2 -1.0 1.0 1.0 A 285.0 285.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K1 AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1.0 260.0 260.0 178 179 180 182 184 65 85 89 158 160 159 161.0 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4
RPS6KA4-1 AF-O75676-K3A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 5.8781 13.3453 BLAminus -137.86, 174.13 57.75, 77.02 -80.17, 14.68 304.16, 99.37 -63.32, -16.55 in-in in 8.7027 Saltbr-in 2.6232 HRD-in -79.41, -52.95 68.65, 0.29 in-in-in SNCiii in-in ActLoopNT-in 2.8836 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.69, 162.48 APE9-dihe-na 107.74, -177.94 APE8-dihe-in -90.07, 132.25 APE8-rot-in 304.86 APE67-dihe-in -59.91, -31.29 -62.41, -36.29 APE12-dist-in 8.3402 APE11-dist-in 11.5249 APE10-dist-in 5.7751 APE9-dist-in 3.8979 None None None AF2 -1.0 1.0 1.0 A 285.0 285.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K3 AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1.0 260.0 260.0 178 179 180 182 184 65 85 89 158 160 159 161.0 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4

AGC_RPS6KA4-1 (Ribosomal protein S6 kinase alpha-4)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O75676-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA4-1 KS6A4_HUMAN AF-O75676-K1A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 6.5976 13.7105 BLAminus -124.98, -168.39 42.55, 70.55 -80.59, 14.7 297.97, 83.91 -61.19, -20.29 in-in in 8.7699 Saltbr-in 2.6042 HRD-in -82.76, -47.29 63.76, 4.18 in-in-in SNCiii in-in ActLoopNT-in 2.9195 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.03, 161.17 APE9-dihe-na 111.84, 169.32 APE8-dihe-in -72.29, 131.49 APE8-rot-in 292.11 APE67-dihe-in -60.98, -29.84 -59.69, -36.55 APE12-dist-in 8.5409 APE11-dist-in 11.5169 APE10-dist-in 5.7607 APE9-dist-in 3.5937 None None None AF2 -1.0 1.0 1.0 A 285.0 285.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K1 Homo sapiens AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1.0 260.0 260.0 178 179 180 182 184 65 85 89 158 160 159 161.0 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4
RPS6KA4-1 KS6A4_HUMAN AF-O75676-K3A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 5.8781 13.3453 BLAminus -137.86, 174.13 57.75, 77.02 -80.17, 14.68 304.16, 99.37 -63.32, -16.55 in-in in 8.7027 Saltbr-in 2.6232 HRD-in -79.41, -52.95 68.65, 0.29 in-in-in SNCiii in-in ActLoopNT-in 2.8836 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.69, 162.48 APE9-dihe-na 107.74, -177.94 APE8-dihe-in -90.07, 132.25 APE8-rot-in 304.86 APE67-dihe-in -59.91, -31.29 -62.41, -36.29 APE12-dist-in 8.3402 APE11-dist-in 11.5249 APE10-dist-in 5.7751 APE9-dist-in 3.8979 None None None AF2 -1.0 1.0 1.0 A 285.0 285.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K3 Homo sapiens AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1.0 260.0 260.0 178 179 180 182 184 65 85 89 158 160 159 161.0 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4

AGC_RPS6KA4-1 (Ribosomal protein S6 kinase alpha-4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name