AGC_RPS6KA2-1 (Ribosomal protein S6 kinase alpha-2)

Total number of chains: 2
Active chains: 2
Uniprot: KS6A2_HUMAN
Kinase Domain Residues: 59 - 318
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q15349-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA2-1 AF-Q15349-K1A Q15349 51 326 733.0 No_ligand No_ligand Active DFGin 6.5598 14.2976 BLAminus -128.83, -162.98 39.17, 62.6 -73.7, 13.33 288.23, 79.39 -63.05, -17.58 in-in in 8.7464 Saltbr-in 2.6179 HRD-in -82.39, -49.82 64.45, 9.53 in-in-in SNCiii in-in ActLoopNT-in 2.8943 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.56, 163.19 APE9-dihe-na 114.31, 169.62 APE8-dihe-in -69.73, 130.78 APE8-rot-in 293.85 APE67-dihe-in -60.4, -27.19 -59.3, -42.05 APE12-dist-in 8.3994 APE11-dist-in 11.4439 APE10-dist-in 5.6991 APE9-dist-in 3.5393 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 28 28 0 [[59, 318], [415, 672]] 2.0 AF-Q15349-K1 AGC_RPS6KA2-1_HUMAN AGC 6.1e-97 329.7 1.0 260.0 260.0 201 202 203 205 207 91 109 113 181 183 182 184.0 241 229 224 223 222 221 220 219 218 139 Ribosomal protein S6 kinase alpha-2
RPS6KA2-1 AF-Q15349-K3A Q15349 51 326 733.0 No_ligand No_ligand Active DFGin 6.4336 14.1588 BLAminus -128.23, -175.81 52.4, 64.67 -72.62, 10.99 294.75, 82.08 -64.43, -12.72 in-in in 8.6258 Saltbr-in 2.6429 HRD-in -85.46, -48.02 66.82, 11.67 in-in-in SNCiii in-in ActLoopNT-in 2.8436 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.59, 164.28 APE9-dihe-na 111.5, 172.79 APE8-dihe-in -74.02, 136.08 APE8-rot-in 294.1 APE67-dihe-in -63.58, -25.11 -70.41, -35.48 APE12-dist-in 8.3739 APE11-dist-in 11.4208 APE10-dist-in 5.655 APE9-dist-in 3.3875 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 28 28 0 [[59, 318], [415, 672]] 2.0 AF-Q15349-K3 AGC_RPS6KA2-1_HUMAN AGC 6.1e-97 329.7 1.0 260.0 260.0 201 202 203 205 207 91 109 113 181 183 182 184.0 241 229 224 223 222 221 220 219 218 139 Ribosomal protein S6 kinase alpha-2

AGC_RPS6KA2-1 (Ribosomal protein S6 kinase alpha-2)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q15349-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA2-1 KS6A2_HUMAN AF-Q15349-K1A Q15349 51 326 733.0 No_ligand No_ligand Active DFGin 6.5598 14.2976 BLAminus -128.83, -162.98 39.17, 62.6 -73.7, 13.33 288.23, 79.39 -63.05, -17.58 in-in in 8.7464 Saltbr-in 2.6179 HRD-in -82.39, -49.82 64.45, 9.53 in-in-in SNCiii in-in ActLoopNT-in 2.8943 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.56, 163.19 APE9-dihe-na 114.31, 169.62 APE8-dihe-in -69.73, 130.78 APE8-rot-in 293.85 APE67-dihe-in -60.4, -27.19 -59.3, -42.05 APE12-dist-in 8.3994 APE11-dist-in 11.4439 APE10-dist-in 5.6991 APE9-dist-in 3.5393 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 28 28 0 [[59, 318], [415, 672]] 2.0 AF-Q15349-K1 Homo sapiens AGC_RPS6KA2-1_HUMAN AGC 6.1e-97 329.7 1.0 260.0 260.0 201 202 203 205 207 91 109 113 181 183 182 184.0 241 229 224 223 222 221 220 219 218 139 Ribosomal protein S6 kinase alpha-2
RPS6KA2-1 KS6A2_HUMAN AF-Q15349-K3A Q15349 51 326 733.0 No_ligand No_ligand Active DFGin 6.4336 14.1588 BLAminus -128.23, -175.81 52.4, 64.67 -72.62, 10.99 294.75, 82.08 -64.43, -12.72 in-in in 8.6258 Saltbr-in 2.6429 HRD-in -85.46, -48.02 66.82, 11.67 in-in-in SNCiii in-in ActLoopNT-in 2.8436 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.59, 164.28 APE9-dihe-na 111.5, 172.79 APE8-dihe-in -74.02, 136.08 APE8-rot-in 294.1 APE67-dihe-in -63.58, -25.11 -70.41, -35.48 APE12-dist-in 8.3739 APE11-dist-in 11.4208 APE10-dist-in 5.655 APE9-dist-in 3.3875 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 28 28 0 [[59, 318], [415, 672]] 2.0 AF-Q15349-K3 Homo sapiens AGC_RPS6KA2-1_HUMAN AGC 6.1e-97 329.7 1.0 260.0 260.0 201 202 203 205 207 91 109 113 181 183 182 184.0 241 229 224 223 222 221 220 219 218 139 Ribosomal protein S6 kinase alpha-2

AGC_RPS6KA2-1 (Ribosomal protein S6 kinase alpha-2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name