AGC_PRKG2 (cGMP-dependent protein kinase 2)

Total number of chains: 2
Active chains: 2
Uniprot: KGP2_HUMAN
Kinase Domain Residues: 453 - 711
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q13237-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PRKG2 AF-Q13237-K1A Q13237 445 719 762.0 No_ligand No_ligand Active DFGin 6.752 14.0817 BLAminus -119.48, -168.56 40.28, 72.03 -81.07, 22.48 279.52, 70.99 -61.25, -29.42 in-in in 9.0965 Saltbr-in 2.6337 HRD-in -88.44, -50.44 65.17, 6.27 in-in-in SNCiii in-in ActLoopNT-in 2.9333 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.09, 174.87 APE9-dihe-na 104.38, 165.11 APE8-dihe-in -75.18, 129.23 APE8-rot-in 301.17 APE67-dihe-in -67.52, -20.75 -48.21, -43.33 APE12-dist-in 7.9645 APE11-dist-in 11.1921 APE10-dist-in 5.5654 APE9-dist-in 3.5161 None None None AF2 -1.0 1.0 1.0 A 275.0 275.0 0 27 27 0 [[453, 711]] 1.0 AF-Q13237-K1 AGC_PRKG2_HUMAN AGC 3.3e-83 284.7 2.0 259.0 258.0 593 594 595 597 599 482 501 505 573 575 574 576.0 632 620 615 614 613 612 611 610 609 531 cGMP-dependent protein kinase 2
PRKG2 AF-Q13237-K3A Q13237 445 719 762.0 No_ligand No_ligand Active DFGin 6.5021 14.1531 BLAminus -125.77, -178.87 48.72, 84.0 -89.45, 17.56 282.99, 76.2 -58.9, -27.76 in-in in 9.0959 Saltbr-in 2.6444 HRD-in -88.18, -50.21 69.86, 1.4 in-in-in SNCiii in-in ActLoopNT-in 2.9048 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.03, 171.58 APE9-dihe-na 102.04, 166.89 APE8-dihe-in -72.95, 132.54 APE8-rot-in 286.13 APE67-dihe-in -67.36, -20.13 -48.32, -44.14 APE12-dist-in 7.6851 APE11-dist-in 10.9859 APE10-dist-in 5.4843 APE9-dist-in 3.7247 None None None AF2 -1.0 1.0 1.0 A 275.0 275.0 0 27 27 0 [[453, 711]] 1.0 AF-Q13237-K3 AGC_PRKG2_HUMAN AGC 3.3e-83 284.7 2.0 259.0 258.0 593 594 595 597 599 482 501 505 573 575 574 576.0 632 620 615 614 613 612 611 610 609 531 cGMP-dependent protein kinase 2

AGC_PRKG2 (cGMP-dependent protein kinase 2)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q13237-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PRKG2 KGP2_HUMAN AF-Q13237-K1A Q13237 445 719 762.0 No_ligand No_ligand Active DFGin 6.752 14.0817 BLAminus -119.48, -168.56 40.28, 72.03 -81.07, 22.48 279.52, 70.99 -61.25, -29.42 in-in in 9.0965 Saltbr-in 2.6337 HRD-in -88.44, -50.44 65.17, 6.27 in-in-in SNCiii in-in ActLoopNT-in 2.9333 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.09, 174.87 APE9-dihe-na 104.38, 165.11 APE8-dihe-in -75.18, 129.23 APE8-rot-in 301.17 APE67-dihe-in -67.52, -20.75 -48.21, -43.33 APE12-dist-in 7.9645 APE11-dist-in 11.1921 APE10-dist-in 5.5654 APE9-dist-in 3.5161 None None None AF2 -1.0 1.0 1.0 A 275.0 275.0 0 27 27 0 [[453, 711]] 1.0 AF-Q13237-K1 Homo sapiens AGC_PRKG2_HUMAN AGC 3.3e-83 284.7 2.0 259.0 258.0 593 594 595 597 599 482 501 505 573 575 574 576.0 632 620 615 614 613 612 611 610 609 531 cGMP-dependent protein kinase 2
PRKG2 KGP2_HUMAN AF-Q13237-K3A Q13237 445 719 762.0 No_ligand No_ligand Active DFGin 6.5021 14.1531 BLAminus -125.77, -178.87 48.72, 84.0 -89.45, 17.56 282.99, 76.2 -58.9, -27.76 in-in in 9.0959 Saltbr-in 2.6444 HRD-in -88.18, -50.21 69.86, 1.4 in-in-in SNCiii in-in ActLoopNT-in 2.9048 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.03, 171.58 APE9-dihe-na 102.04, 166.89 APE8-dihe-in -72.95, 132.54 APE8-rot-in 286.13 APE67-dihe-in -67.36, -20.13 -48.32, -44.14 APE12-dist-in 7.6851 APE11-dist-in 10.9859 APE10-dist-in 5.4843 APE9-dist-in 3.7247 None None None AF2 -1.0 1.0 1.0 A 275.0 275.0 0 27 27 0 [[453, 711]] 1.0 AF-Q13237-K3 Homo sapiens AGC_PRKG2_HUMAN AGC 3.3e-83 284.7 2.0 259.0 258.0 593 594 595 597 599 482 501 505 573 575 574 576.0 632 620 615 614 613 612 611 610 609 531 cGMP-dependent protein kinase 2

AGC_PRKG2 (cGMP-dependent protein kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name