AGC_PRKCH (Protein kinase C eta type)

Total number of chains: 5
Active chains: 4
Family: AGC
Uniprot: KPCL_HUMAN
Kinase Domain Residues: 355 - 614
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-P24723-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-P24723-K1A 347 622 683.0 No_ligand No_ligand Active DFGin 5.749 12.772 BLAminus -106.1, -173.16 38.28, 91.09 -97.14, 16.07 304.8, 94.12 -62.68, -25.89 in-in in 8.525 Saltbr-in 2.617 HRD-in -85.22, -48.7 63.75, -0.17 in-in-in SNCiii in-in ActLoopNT-in 2.903 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.59, 159.8 APE9-dihe-na 134.84, 173.72 APE8-dihe-in -79.82, 127.49 APE8-rot-in 296.6 APE67-dihe-in -67.71, -17.85 -43.24, -50.27 APE12-dist-in 8.71 APE11-dist-in 11.608 APE10-dist-in 5.964 APE9-dist-in 3.432 None None None AF2 -1.0 1.0 1.0 A 276 276 0 0 0 0 [[355, 614]] 1.0 AF-P24723-K1 AGC_PRKCH_HUMAN AGC 6.9e-98 332.8 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
AF-P24723-K3A 347 622 683.0 No_ligand No_ligand Active DFGin 5.486 12.838 BLAminus -113.3, -173.79 33.92, 96.43 -97.69, 15.91 306.27, 99.4 -63.08, -28.8 in-in in 8.388 Saltbr-in 2.625 HRD-in -87.28, -49.72 68.32, -5.12 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.76, 163.25 APE9-dihe-na 130.19, 175.68 APE8-dihe-in -87.39, 133.47 APE8-rot-in 293.76 APE67-dihe-in -64.49, -20.83 -48.29, -47.55 APE12-dist-in 8.681 APE11-dist-in 11.638 APE10-dist-in 6.033 APE9-dist-in 3.433 None None None AF2 -1.0 1.0 1.0 A 276 276 0 0 0 0 [[355, 614]] 1.0 AF-P24723-K3 AGC_PRKCH_HUMAN AGC 6.9e-98 332.8 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
8FP1A 349 676 683.0 XXF:9000 Type1 Active DFGin 6.04 12.861 BLAminus -134.17, 160.39 76.6, 103.68 -113.44, 14.82 306.37, 103.97 -62.81, -37.48 in-in in 8.529 Saltbr-in 2.747 HRD-in -71.28, -48.4 60.66, 8.21 in-in-in SNCiii in-in ActLoopNT-in 3.042 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -168.52, 169.89 APE9-dihe-na 121.68, 166.05 APE8-dihe-in -83.39, 128.15 APE8-rot-in 297.95 APE67-dihe-in -61.25, -27.98 -43.8, -44.17 APE12-dist-in 8.666 APE11-dist-in 11.701 APE10-dist-in 6.365 APE9-dist-in 3.566 S675E TPO513,TPO656 TPO513,TPO656 XRAY 1.85 0.2 0.234 A 353 328 0 0 0 0 [[355, 614]] 1.0 8fp1 AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
8FP3A 349 679 683.0 Y3I:9000 Type1 Active DFGin 6.22 13.226 BLAminus -127.87, 165.42 68.91, 93.86 -107.42, 16.9 300.66, 99.02 -64.47, -31.74 in-in in 8.835 Saltbr-in 2.953 HRD-in -62.84, -58.95 67.06, -3.18 in-in-in SNCiii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.98, 170.15 APE9-dihe-na 118.17, 177.41 APE8-dihe-in -88.28, 125.69 APE8-rot-in 312.19 APE67-dihe-in -66.78, -22.74 -44.71, -43.76 APE12-dist-in 8.702 APE11-dist-in 11.681 APE10-dist-in 6.178 APE9-dist-in 3.426 S675E TPO513,TPO656 TPO513,TPO656 XRAY 2.3 0.198 0.256 A 353 331 0 0 0 0 [[355, 614]] 1.0 8fp3 AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
3TXOA 353 679 683.0 07U:1 Type1 Inactive DFGin 6.194 12.867 BLAminus -131.98, 154.73 77.42, 93.31 -108.7, 22.52 305.55, 91.59 -71.89, -20.94 in-in in 8.675 Saltbr-in 2.739 HRD-in -77.21, -43.2 71.88, -16.47 in-in-out SNCiio in-out ActLoopNT-in 3.033 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -168.17 APE8-dihe-in -81.7, 128.35 APE8-rot-in 299.86 APE67-dihe-in -64.49, -27.49 -50.95, -35.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 25.627 S675E TPO656 TPO656 XRAY 2.05 0.212 0.241 A 353 318 9 0 0 9 [[355, 614]] 1.0 3txo AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type

AGC_PRKCH (Protein kinase C eta type)

Total number of chains: 5
Active chains: 4
Family: AGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-P24723-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KPCL_HUMAN AF-P24723-K1A P24723 347 622 683.0 No_ligand No_ligand Active DFGin 5.749 12.772 BLAminus -106.1, -173.16 38.28, 91.09 -97.14, 16.07 304.8, 94.12 -62.68, -25.89 in-in in 8.525 Saltbr-in 2.617 HRD-in -85.22, -48.7 63.75, -0.17 in-in-in SNCiii in-in ActLoopNT-in 2.903 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.59, 159.8 APE9-dihe-na 134.84, 173.72 APE8-dihe-in -79.82, 127.49 APE8-rot-in 296.6 APE67-dihe-in -67.71, -17.85 -43.24, -50.27 APE12-dist-in 8.71 APE11-dist-in 11.608 APE10-dist-in 5.964 APE9-dist-in 3.432 None None None AF2 -1.0 1.0 1.0 A 276 276 0 0 0 0 [[355, 614]] 1.0 AF-P24723-K1 Homo sapiens AGC_PRKCH_HUMAN AGC 6.9e-98 332.8 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
KPCL_HUMAN AF-P24723-K3A P24723 347 622 683.0 No_ligand No_ligand Active DFGin 5.486 12.838 BLAminus -113.3, -173.79 33.92, 96.43 -97.69, 15.91 306.27, 99.4 -63.08, -28.8 in-in in 8.388 Saltbr-in 2.625 HRD-in -87.28, -49.72 68.32, -5.12 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.76, 163.25 APE9-dihe-na 130.19, 175.68 APE8-dihe-in -87.39, 133.47 APE8-rot-in 293.76 APE67-dihe-in -64.49, -20.83 -48.29, -47.55 APE12-dist-in 8.681 APE11-dist-in 11.638 APE10-dist-in 6.033 APE9-dist-in 3.433 None None None AF2 -1.0 1.0 1.0 A 276 276 0 0 0 0 [[355, 614]] 1.0 AF-P24723-K3 Homo sapiens AGC_PRKCH_HUMAN AGC 6.9e-98 332.8 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
KPCL_HUMAN 8FP1A P24723 349 676 683.0 XXF:9000 Type1 Active DFGin 6.04 12.861 BLAminus -134.17, 160.39 76.6, 103.68 -113.44, 14.82 306.37, 103.97 -62.81, -37.48 in-in in 8.529 Saltbr-in 2.747 HRD-in -71.28, -48.4 60.66, 8.21 in-in-in SNCiii in-in ActLoopNT-in 3.042 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -168.52, 169.89 APE9-dihe-na 121.68, 166.05 APE8-dihe-in -83.39, 128.15 APE8-rot-in 297.95 APE67-dihe-in -61.25, -27.98 -43.8, -44.17 APE12-dist-in 8.666 APE11-dist-in 11.701 APE10-dist-in 6.365 APE9-dist-in 3.566 S675E TPO513,TPO656 TPO513,TPO656 XRAY 1.85 0.2 0.234 A 353 328 0 0 0 0 [[355, 614]] 1.0 8fp1 Homo sapiens AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
KPCL_HUMAN 8FP3A P24723 349 679 683.0 Y3I:9000 Type1 Active DFGin 6.22 13.226 BLAminus -127.87, 165.42 68.91, 93.86 -107.42, 16.9 300.66, 99.02 -64.47, -31.74 in-in in 8.835 Saltbr-in 2.953 HRD-in -62.84, -58.95 67.06, -3.18 in-in-in SNCiii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -165.98, 170.15 APE9-dihe-na 118.17, 177.41 APE8-dihe-in -88.28, 125.69 APE8-rot-in 312.19 APE67-dihe-in -66.78, -22.74 -44.71, -43.76 APE12-dist-in 8.702 APE11-dist-in 11.681 APE10-dist-in 6.178 APE9-dist-in 3.426 S675E TPO513,TPO656 TPO513,TPO656 XRAY 2.3 0.198 0.256 A 353 331 0 0 0 0 [[355, 614]] 1.0 8fp3 Homo sapiens AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type
KPCL_HUMAN 3TXOA P24723 353 679 683.0 07U:1 Type1 Inactive DFGin 6.194 12.867 BLAminus -131.98, 154.73 77.42, 93.31 -108.7, 22.52 305.55, 91.59 -71.89, -20.94 in-in in 8.675 Saltbr-in 2.739 HRD-in -77.21, -43.2 71.88, -16.47 in-in-out SNCiio in-out ActLoopNT-in 3.033 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -168.17 APE8-dihe-in -81.7, 128.35 APE8-rot-in 299.86 APE67-dihe-in -64.49, -27.49 -50.95, -35.14 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 25.627 S675E TPO656 TPO656 XRAY 2.05 0.212 0.241 A 353 318 9 0 0 9 [[355, 614]] 1.0 3txo Homo sapiens AGC_PRKCH_HUMAN AGC 1.6e-97 331.6 1 260 260 496 497 498 500 502 384 403 407 476 478 477 479 536 524 519 518 517 516 515 514 513 434 Protein kinase C eta type

AGC_PRKCH (Protein kinase C eta type)

Total number of chains: 0
Active chains: 0
Family: AGC
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name