| Gene | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PAK6 | AF-Q9NQU5-K1A | Q9NQU5 | 399 | 666 | 681.0 | No_ligand | No_ligand | Active | DFGin | 5.9956 | 13.3749 | BLAminus | -134.37, -175.73 | 64.14, 51.11 | -74.82, 7.36 | 304.32, 104.32 | -60.02, -34.48 | in-in | in | 7.482 | Saltbr-in | 2.7064 | HRD-in | -70.99, -51.55 | 65.92, 9.36 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.7864 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -145.39, 162.53 | APE9-dihe-na | 109.38, 179.76 | APE8-dihe-in | -84.5, 126.56 | APE8-rot-in | 303.38 | APE67-dihe-in | -77.88, -20.54 | -49.12, -41.56 | APE12-dist-in | 9.0587 | APE11-dist-in | 11.6174 | APE10-dist-in | 5.6611 | APE9-dist-in | 3.2504 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 268.0 | 268.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | AF-Q9NQU5-K1 | STE_PAK6_HUMAN | STE | 1.7e-91 | 312.1 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | AF-Q9NQU5-K3A | Q9NQU5 | 399 | 666 | 681.0 | No_ligand | No_ligand | Active | DFGin | 6.973 | 14.8672 | BLAminus | -132.74, -172.11 | 59.56, 51.25 | -73.68, 15.14 | 292.99, 83.96 | -58.39, -25.06 | in-in | in | 8.1627 | Saltbr-in | 2.8382 | HRD-in | -74.74, -48.3 | 66.41, 3.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8543 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -137.76, 139.95 | APE9-dihe-na | 128.99, 169.95 | APE8-dihe-in | -82.08, 126.62 | APE8-rot-in | 298.52 | APE67-dihe-in | -78.9, -18.18 | -44.18, -42.51 | APE12-dist-in | 9.1408 | APE11-dist-in | 11.5336 | APE10-dist-in | 5.6935 | APE9-dist-in | 3.0642 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 268.0 | 268.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | AF-Q9NQU5-K3 | STE_PAK6_HUMAN | STE | 1.7e-91 | 312.1 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | 4KS7A | Q9NQU5 | 386 | 672 | 681.0 | 7KC:702 | Type1 | Active | DFGin | 6.3989 | 14.0699 | BLAminus | -131.53, -164.02 | 58.87, 58.03 | -84.12, 9.46 | 299.86, 106.48 | -62.0, -36.31 | in-in | in | 6.6476 | Saltbr-in | 2.7816 | HRD-in | -71.32, -50.61 | 76.7, -3.92 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8425 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -137.42, 131.66 | APE9-dihe-na | 146.46, -164.78 | APE8-dihe-in | -110.2, 122.65 | APE8-rot-in | 303.96 | APE67-dihe-in | -64.79, -19.68 | -38.25, -57.9 | APE12-dist-in | 9.5278 | APE11-dist-in | 11.5642 | APE10-dist-in | 5.9068 | APE9-dist-in | 3.344 | None | SEP560 | SEP560 | XRAY | 1.4 | 0.195 | 0.217 | A | 292.0 | 287.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | 4ks7 | STE_PAK6_HUMAN | STE | 2.4e-91 | 311.6 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | 4KS8A | Q9NQU5 | 385 | 671 | 681.0 | B49:701 | Type1 | Active | DFGin | 6.3448 | 13.5239 | BLAminus | -140.01, -170.23 | 63.35, 61.58 | -89.05, 6.98 | 299.26, 108.58 | -57.68, -33.0 | in-in | in | 6.9584 | Saltbr-in | 2.9133 | HRD-in | -67.27, -52.49 | 75.45, -5.04 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8012 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -128.89, 129.35 | APE9-dihe-na | 153.97, -169.18 | APE8-dihe-in | -106.27, 121.21 | APE8-rot-in | 308.12 | APE67-dihe-in | -63.35, -19.7 | -31.2, -62.7 | APE12-dist-in | 9.8713 | APE11-dist-in | 11.5056 | APE10-dist-in | 5.7538 | APE9-dist-in | 3.36 | None | SEP560 | SEP560 | XRAY | 1.95 | 0.22 | 0.261 | A | 292.0 | 287.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | 4ks8 | STE_PAK6_HUMAN | STE | 2.4e-91 | 311.6 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | 2C30A | Q9NQU5 | 385 | 674 | 681.0 | No_ligand | No_ligand | Inactive | DFGin | 7.3766 | 16.4314 | BLAminus | -134.69, -166.33 | 59.54, 59.75 | -84.16, 17.29 | 284.94, 79.67 | -48.96, -37.48 | out-out | out | 10.6099 | Saltbr-out | 4.7217 | HRD-in | -77.12, -50.35 | 73.19, 0.7 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.8866 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -133.3, 159.49 | APE9-dihe-na | 123.06, -161.66 | APE8-dihe-in | -118.32, 126.94 | APE8-rot-in | 303.64 | APE67-dihe-in | -65.44, -18.81 | -40.03, -54.6 | APE12-dist-in | 8.6902 | APE11-dist-in | 11.4684 | APE10-dist-in | 5.5442 | APE9-dist-in | 3.3318 | None | SEP560 | SEP560 | XRAY | 1.6 | 0.198 | 0.222 | A | 321.0 | 290.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | 2c30 | STE_PAK6_HUMAN | STE | 3.3e-91 | 311.2 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PAK6 | PAK6_HUMAN | AF-Q9NQU5-K1A | Q9NQU5 | 399 | 666 | 681.0 | No_ligand | No_ligand | Active | DFGin | 5.9956 | 13.3749 | BLAminus | -134.37, -175.73 | 64.14, 51.11 | -74.82, 7.36 | 304.32, 104.32 | -60.02, -34.48 | in-in | in | 7.482 | Saltbr-in | 2.7064 | HRD-in | -70.99, -51.55 | 65.92, 9.36 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.7864 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -145.39, 162.53 | APE9-dihe-na | 109.38, 179.76 | APE8-dihe-in | -84.5, 126.56 | APE8-rot-in | 303.38 | APE67-dihe-in | -77.88, -20.54 | -49.12, -41.56 | APE12-dist-in | 9.0587 | APE11-dist-in | 11.6174 | APE10-dist-in | 5.6611 | APE9-dist-in | 3.2504 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 268.0 | 268.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | AF-Q9NQU5-K1 | Homo sapiens | STE_PAK6_HUMAN | STE | 1.7e-91 | 312.1 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | PAK6_HUMAN | AF-Q9NQU5-K3A | Q9NQU5 | 399 | 666 | 681.0 | No_ligand | No_ligand | Active | DFGin | 6.973 | 14.8672 | BLAminus | -132.74, -172.11 | 59.56, 51.25 | -73.68, 15.14 | 292.99, 83.96 | -58.39, -25.06 | in-in | in | 8.1627 | Saltbr-in | 2.8382 | HRD-in | -74.74, -48.3 | 66.41, 3.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8543 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -137.76, 139.95 | APE9-dihe-na | 128.99, 169.95 | APE8-dihe-in | -82.08, 126.62 | APE8-rot-in | 298.52 | APE67-dihe-in | -78.9, -18.18 | -44.18, -42.51 | APE12-dist-in | 9.1408 | APE11-dist-in | 11.5336 | APE10-dist-in | 5.6935 | APE9-dist-in | 3.0642 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 268.0 | 268.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | AF-Q9NQU5-K3 | Homo sapiens | STE_PAK6_HUMAN | STE | 1.7e-91 | 312.1 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | PAK6_HUMAN | 4KS7A | Q9NQU5 | 386 | 672 | 681.0 | 7KC:702 | Type1 | Active | DFGin | 6.3989 | 14.0699 | BLAminus | -131.53, -164.02 | 58.87, 58.03 | -84.12, 9.46 | 299.86, 106.48 | -62.0, -36.31 | in-in | in | 6.6476 | Saltbr-in | 2.7816 | HRD-in | -71.32, -50.61 | 76.7, -3.92 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8425 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -137.42, 131.66 | APE9-dihe-na | 146.46, -164.78 | APE8-dihe-in | -110.2, 122.65 | APE8-rot-in | 303.96 | APE67-dihe-in | -64.79, -19.68 | -38.25, -57.9 | APE12-dist-in | 9.5278 | APE11-dist-in | 11.5642 | APE10-dist-in | 5.9068 | APE9-dist-in | 3.344 | None | SEP560 | SEP560 | XRAY | 1.4 | 0.195 | 0.217 | A | 292.0 | 287.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | 4ks7 | Homo sapiens | STE_PAK6_HUMAN | STE | 2.4e-91 | 311.6 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | PAK6_HUMAN | 4KS8A | Q9NQU5 | 385 | 671 | 681.0 | B49:701 | Type1 | Active | DFGin | 6.3448 | 13.5239 | BLAminus | -140.01, -170.23 | 63.35, 61.58 | -89.05, 6.98 | 299.26, 108.58 | -57.68, -33.0 | in-in | in | 6.9584 | Saltbr-in | 2.9133 | HRD-in | -67.27, -52.49 | 75.45, -5.04 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8012 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -128.89, 129.35 | APE9-dihe-na | 153.97, -169.18 | APE8-dihe-in | -106.27, 121.21 | APE8-rot-in | 308.12 | APE67-dihe-in | -63.35, -19.7 | -31.2, -62.7 | APE12-dist-in | 9.8713 | APE11-dist-in | 11.5056 | APE10-dist-in | 5.7538 | APE9-dist-in | 3.36 | None | SEP560 | SEP560 | XRAY | 1.95 | 0.22 | 0.261 | A | 292.0 | 287.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | 4ks8 | Homo sapiens | STE_PAK6_HUMAN | STE | 2.4e-91 | 311.6 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| PAK6 | PAK6_HUMAN | 2C30A | Q9NQU5 | 385 | 674 | 681.0 | No_ligand | No_ligand | Inactive | DFGin | 7.3766 | 16.4314 | BLAminus | -134.69, -166.33 | 59.54, 59.75 | -84.16, 17.29 | 284.94, 79.67 | -48.96, -37.48 | out-out | out | 10.6099 | Saltbr-out | 4.7217 | HRD-in | -77.12, -50.35 | 73.19, 0.7 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.8866 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -133.3, 159.49 | APE9-dihe-na | 123.06, -161.66 | APE8-dihe-in | -118.32, 126.94 | APE8-rot-in | 303.64 | APE67-dihe-in | -65.44, -18.81 | -40.03, -54.6 | APE12-dist-in | 8.6902 | APE11-dist-in | 11.4684 | APE10-dist-in | 5.5442 | APE9-dist-in | 3.3318 | None | SEP560 | SEP560 | XRAY | 1.6 | 0.198 | 0.222 | A | 321.0 | 290.0 | 0 | 28 | 28 | 0 | [[407, 658]] | 1.0 | 2c30 | Homo sapiens | STE_PAK6_HUMAN | STE | 3.3e-91 | 311.2 | 4.0 | 257.0 | 254.0 | 543 | 544 | 545 | 547 | 549 | 436 | 452 | 456 | 523 | 525 | 524 | 526.0 | 583 | 571 | 566 | 565 | 564 | 563 | 562 | 561 | 560 | 482 | Serine/threonine-protein kinase PAK 6 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|