STE_PAK6 (Serine/threonine-protein kinase PAK 6)

Total number of chains: 5
Active chains: 1
Family: STE
Uniprot: PAK6_HUMAN
Kinase Domain Residues: 407 - 658
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-Q9NQU5-K3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q9NQU5-K3A 399 666 681.0 No_ligand No_ligand Active DFGin 6.094 14.318 BLAminus DFGAsp-rot-in -138.1064, -173.827 62.1437, 46.9317 204.9096, 27.1377 -71.3788, 3.2938 292.212, 89.5267 -54.6601, -32.4754 in-in in 6.866 Saltbr-in 2.731 HRD-in -72.9476, -47.4868 65.8421, 15.1883 in-in-in SNCiii in-in ActLoopNT-in 2.833 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.0939, 143.7393 APE9-dihe-na 123.6296, 178.1281 APE8-dihe-in -88.8886, 128.823 APE8-rot-in 300.9816 APE67-dihe-in -78.3475, -17.7617 -46.9855, -40.511 APE12-dist-in 9.043 APE11-dist-in 11.586 APE10-dist-in 5.811 APE9-dist-in 3.01 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[407, 658]] 1.0 AF-Q9NQU5-K3 STE_PAK6_HUMAN STE 1.8e-91 312.1 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
AF-Q9NQU5-K1A 399 666 681.0 No_ligand No_ligand Inactive DFGin 5.996 13.375 BLAminus DFGAsp-rot-out -134.37, -175.73 64.14, 51.11 281.69, -22.89 -74.82, 7.36 304.32, 104.32 -60.02, -34.48 in-in in 7.482 Saltbr-in 2.706 HRD-in -70.99, -51.55 65.92, 9.36 in-in-in SNCiii in-in ActLoopNT-in 2.786 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.39, 162.53 APE9-dihe-na 109.38, 179.76 APE8-dihe-in -84.5, 126.56 APE8-rot-in 303.38 APE67-dihe-in -77.88, -20.54 -49.12, -41.56 APE12-dist-in 9.059 APE11-dist-in 11.617 APE10-dist-in 5.661 APE9-dist-in 3.25 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[407, 658]] 1.0 AF-Q9NQU5-K1 STE_PAK6_HUMAN STE 1.8e-91 312.1 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
2C30A 385 674 681.0 No_ligand No_ligand Inactive DFGin 7.377 16.431 BLAminus DFGAsp-rot-out -134.69, -166.33 59.54, 59.75 288.62, -6.62 -84.16, 17.29 284.94, 79.67 -48.96, -37.48 out-out out 10.61 Saltbr-out 4.722 HRD-in -77.12, -50.35 73.19, 0.7 out-in-in SNCoii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 159.49 APE9-dihe-na 123.06, -161.66 APE8-dihe-in -118.32, 126.94 APE8-rot-in 303.64 APE67-dihe-in -65.44, -18.81 -40.03, -54.6 APE12-dist-in 8.69 APE11-dist-in 11.468 APE10-dist-in 5.544 APE9-dist-in 3.332 None SEP560 SEP560 XRAY 1.6 0.198 0.222 A 321 290 0 0 0 0 [[407, 658]] 1.0 2c30 STE_PAK6_HUMAN STE 3.4e-91 311.2 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
4KS7A 386 672 681.0 7KC:702 Type1 Inactive DFGin 6.399 14.07 BLAminus DFGAsp-rot-out -131.53, -164.02 58.87, 58.03 283.73, 2.78 -84.12, 9.46 299.86, 106.48 -62.0, -36.31 in-in in 6.648 Saltbr-in 2.782 HRD-in -71.32, -50.61 76.7, -3.92 in-in-in SNCiii in-in ActLoopNT-in 2.842 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.42, 131.66 APE9-dihe-na 146.46, -164.78 APE8-dihe-in -110.2, 122.65 APE8-rot-in 303.96 APE67-dihe-in -64.79, -19.68 -38.25, -57.9 APE12-dist-in 9.528 APE11-dist-in 11.564 APE10-dist-in 5.907 APE9-dist-in 3.344 None SEP560 SEP560 XRAY 1.4 0.195 0.217 A 292 287 0 0 0 0 [[407, 658]] 1.0 4ks7 STE_PAK6_HUMAN STE 2.4e-91 311.6 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
4KS8A 385 671 681.0 B49:701 Type1 Inactive DFGin 6.345 13.524 BLAminus DFGAsp-rot-out -140.01, -170.23 63.35, 61.58 274.57, 35.94 -89.05, 6.98 299.26, 108.58 -57.68, -33.0 in-in in 6.958 Saltbr-in 2.913 HRD-in -67.27, -52.49 75.45, -5.04 in-in-in SNCiii in-in ActLoopNT-in 2.801 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.89, 129.35 APE9-dihe-na 153.97, -169.18 APE8-dihe-in -106.27, 121.21 APE8-rot-in 308.12 APE67-dihe-in -63.35, -19.7 -31.2, -62.7 APE12-dist-in 9.871 APE11-dist-in 11.506 APE10-dist-in 5.754 APE9-dist-in 3.36 None SEP560 SEP560 XRAY 1.95 0.22 0.261 A 292 287 0 0 0 0 [[407, 658]] 1.0 4ks8 STE_PAK6_HUMAN STE 2.4e-91 311.6 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6

STE_PAK6 (Serine/threonine-protein kinase PAK 6)

Total number of chains: 5
Active chains: 1
Family: STE
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-Q9NQU5-K3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PAK6_HUMAN AF-Q9NQU5-K3A Q9NQU5 399 666 681.0 No_ligand No_ligand Active DFGin 6.094 14.318 BLAminus DFGAsp-rot-in -138.1064, -173.827 62.1437, 46.9317 204.9096, 27.1377 -71.3788, 3.2938 292.212, 89.5267 -54.6601, -32.4754 in-in in 6.866 Saltbr-in 2.731 HRD-in -72.9476, -47.4868 65.8421, 15.1883 in-in-in SNCiii in-in ActLoopNT-in 2.833 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.0939, 143.7393 APE9-dihe-na 123.6296, 178.1281 APE8-dihe-in -88.8886, 128.823 APE8-rot-in 300.9816 APE67-dihe-in -78.3475, -17.7617 -46.9855, -40.511 APE12-dist-in 9.043 APE11-dist-in 11.586 APE10-dist-in 5.811 APE9-dist-in 3.01 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[407, 658]] 1.0 AF-Q9NQU5-K3 Homo sapiens STE_PAK6_HUMAN STE 1.8e-91 312.1 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
PAK6_HUMAN AF-Q9NQU5-K1A Q9NQU5 399 666 681.0 No_ligand No_ligand Inactive DFGin 5.996 13.375 BLAminus DFGAsp-rot-out -134.37, -175.73 64.14, 51.11 281.69, -22.89 -74.82, 7.36 304.32, 104.32 -60.02, -34.48 in-in in 7.482 Saltbr-in 2.706 HRD-in -70.99, -51.55 65.92, 9.36 in-in-in SNCiii in-in ActLoopNT-in 2.786 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.39, 162.53 APE9-dihe-na 109.38, 179.76 APE8-dihe-in -84.5, 126.56 APE8-rot-in 303.38 APE67-dihe-in -77.88, -20.54 -49.12, -41.56 APE12-dist-in 9.059 APE11-dist-in 11.617 APE10-dist-in 5.661 APE9-dist-in 3.25 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[407, 658]] 1.0 AF-Q9NQU5-K1 Homo sapiens STE_PAK6_HUMAN STE 1.8e-91 312.1 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
PAK6_HUMAN 2C30A Q9NQU5 385 674 681.0 No_ligand No_ligand Inactive DFGin 7.377 16.431 BLAminus DFGAsp-rot-out -134.69, -166.33 59.54, 59.75 288.62, -6.62 -84.16, 17.29 284.94, 79.67 -48.96, -37.48 out-out out 10.61 Saltbr-out 4.722 HRD-in -77.12, -50.35 73.19, 0.7 out-in-in SNCoii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 159.49 APE9-dihe-na 123.06, -161.66 APE8-dihe-in -118.32, 126.94 APE8-rot-in 303.64 APE67-dihe-in -65.44, -18.81 -40.03, -54.6 APE12-dist-in 8.69 APE11-dist-in 11.468 APE10-dist-in 5.544 APE9-dist-in 3.332 None SEP560 SEP560 XRAY 1.6 0.198 0.222 A 321 290 0 0 0 0 [[407, 658]] 1.0 2c30 Homo sapiens STE_PAK6_HUMAN STE 3.4e-91 311.2 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
PAK6_HUMAN 4KS7A Q9NQU5 386 672 681.0 7KC:702 Type1 Inactive DFGin 6.399 14.07 BLAminus DFGAsp-rot-out -131.53, -164.02 58.87, 58.03 283.73, 2.78 -84.12, 9.46 299.86, 106.48 -62.0, -36.31 in-in in 6.648 Saltbr-in 2.782 HRD-in -71.32, -50.61 76.7, -3.92 in-in-in SNCiii in-in ActLoopNT-in 2.842 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.42, 131.66 APE9-dihe-na 146.46, -164.78 APE8-dihe-in -110.2, 122.65 APE8-rot-in 303.96 APE67-dihe-in -64.79, -19.68 -38.25, -57.9 APE12-dist-in 9.528 APE11-dist-in 11.564 APE10-dist-in 5.907 APE9-dist-in 3.344 None SEP560 SEP560 XRAY 1.4 0.195 0.217 A 292 287 0 0 0 0 [[407, 658]] 1.0 4ks7 Homo sapiens STE_PAK6_HUMAN STE 2.4e-91 311.6 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6
PAK6_HUMAN 4KS8A Q9NQU5 385 671 681.0 B49:701 Type1 Inactive DFGin 6.345 13.524 BLAminus DFGAsp-rot-out -140.01, -170.23 63.35, 61.58 274.57, 35.94 -89.05, 6.98 299.26, 108.58 -57.68, -33.0 in-in in 6.958 Saltbr-in 2.913 HRD-in -67.27, -52.49 75.45, -5.04 in-in-in SNCiii in-in ActLoopNT-in 2.801 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.89, 129.35 APE9-dihe-na 153.97, -169.18 APE8-dihe-in -106.27, 121.21 APE8-rot-in 308.12 APE67-dihe-in -63.35, -19.7 -31.2, -62.7 APE12-dist-in 9.871 APE11-dist-in 11.506 APE10-dist-in 5.754 APE9-dist-in 3.36 None SEP560 SEP560 XRAY 1.95 0.22 0.261 A 292 287 0 0 0 0 [[407, 658]] 1.0 4ks8 Homo sapiens STE_PAK6_HUMAN STE 2.4e-91 311.6 4 257 254 543 544 545 547 549 436 452 456 523 525 524 526 583 571 566 565 564 563 562 561 560 482 Serine/threonine-protein kinase PAK 6

STE_PAK6 (Serine/threonine-protein kinase PAK 6)

Total number of chains: 0
Active chains: 0
Family: STE
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name