STE_PAK3 (Serine/threonine-protein kinase PAK 3)

Total number of chains: 3
Active chains: 3
Uniprot: PAK3_HUMAN
Kinase Domain Residues: 283 - 534
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-O75914-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PAK3 6FD3A O75914 261 556 559.0 ADP:60603 ATPlike Active DFGin 5.9519 14.1494 BLAminus -133.62, -174.01 64.9, 77.07 -96.85, 18.52 289.09, 83.73 -72.71, -11.5 in-in in 8.938 Saltbr-in 2.7609 HRD-in -71.32, -50.63 74.19, 1.63 in-in-in SNCiii in-in ActLoopNT-in 2.9127 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.75, 147.44 APE9-dihe-na 132.72, -161.48 APE8-dihe-in -114.41, 121.22 APE8-rot-in 305.33 APE67-dihe-in -64.48, -19.99 -44.4, -48.2 APE12-dist-in 8.8491 APE11-dist-in 11.3583 APE10-dist-in 5.5763 APE9-dist-in 3.3396 A537D None T8L436 XRAY 1.52 0.176 0.19 A 300.0 296.0 0 28 28 0 [[283, 534]] 1.0 6fd3 STE_PAK3_HUMAN STE 1.1e-94 322.5 1.0 257.0 257.0 419 420 421 423 425 312 328 332 399 401 400 402.0 459 447 442 441 440 439 438 437 436 358 Serine/threonine-protein kinase PAK 3
PAK3 AF-O75914-K1A O75914 275 542 559.0 No_ligand No_ligand Active DFGin 5.9565 14.0876 BLAminus -132.14, -176.18 59.41, 61.38 -75.54, 13.79 297.0, 90.53 -57.03, -33.73 in-in in 8.4164 Saltbr-in 2.6742 HRD-in -71.8, -49.24 65.42, 10.92 in-in-in SNCiii in-in ActLoopNT-in 2.8622 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.74, 154.91 APE9-dihe-na 121.49, 170.06 APE8-dihe-in -75.28, 127.31 APE8-rot-in 302.17 APE67-dihe-in -70.63, -20.74 -49.24, -47.09 APE12-dist-in 9.075 APE11-dist-in 11.6816 APE10-dist-in 5.856 APE9-dist-in 3.2286 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 28 28 0 [[283, 534]] 1.0 AF-O75914-K1 STE_PAK3_HUMAN STE 7.5e-95 323.0 1.0 257.0 257.0 419 420 421 423 425 312 328 332 399 401 400 402.0 459 447 442 441 440 439 438 437 436 358 Serine/threonine-protein kinase PAK 3
PAK3 AF-O75914-K3A O75914 275 542 559.0 No_ligand No_ligand Active DFGin 5.8036 14.8046 BLAminus -136.32, -175.1 65.13, 61.42 -79.15, 5.3 292.02, 82.41 -58.35, -32.4 in-in in 9.1624 Saltbr-in 2.9638 HRD-in -72.63, -49.65 69.85, 1.97 in-in-in SNCiii in-in ActLoopNT-in 2.8683 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.62, 140.94 APE9-dihe-na 121.04, 177.69 APE8-dihe-in -88.2, 128.79 APE8-rot-in 306.84 APE67-dihe-in -67.63, -21.94 -41.8, -52.86 APE12-dist-in 9.6702 APE11-dist-in 11.8251 APE10-dist-in 5.9411 APE9-dist-in 3.1334 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 28 28 0 [[283, 534]] 1.0 AF-O75914-K3 STE_PAK3_HUMAN STE 7.5e-95 323.0 1.0 257.0 257.0 419 420 421 423 425 312 328 332 399 401 400 402.0 459 447 442 441 440 439 438 437 436 358 Serine/threonine-protein kinase PAK 3

STE_PAK3 (Serine/threonine-protein kinase PAK 3)

Total number of chains: 3
Active chains: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-O75914-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PAK3 PAK3_HUMAN 6FD3A O75914 261 556 559.0 ADP:60603 ATPlike Active DFGin 5.9519 14.1494 BLAminus -133.62, -174.01 64.9, 77.07 -96.85, 18.52 289.09, 83.73 -72.71, -11.5 in-in in 8.938 Saltbr-in 2.7609 HRD-in -71.32, -50.63 74.19, 1.63 in-in-in SNCiii in-in ActLoopNT-in 2.9127 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.75, 147.44 APE9-dihe-na 132.72, -161.48 APE8-dihe-in -114.41, 121.22 APE8-rot-in 305.33 APE67-dihe-in -64.48, -19.99 -44.4, -48.2 APE12-dist-in 8.8491 APE11-dist-in 11.3583 APE10-dist-in 5.5763 APE9-dist-in 3.3396 A537D None T8L436 XRAY 1.52 0.176 0.19 A 300.0 296.0 0 28 28 0 [[283, 534]] 1.0 6fd3 Homo sapiens STE_PAK3_HUMAN STE 1.1e-94 322.5 1.0 257.0 257.0 419 420 421 423 425 312 328 332 399 401 400 402.0 459 447 442 441 440 439 438 437 436 358 Serine/threonine-protein kinase PAK 3
PAK3 PAK3_HUMAN AF-O75914-K1A O75914 275 542 559.0 No_ligand No_ligand Active DFGin 5.9565 14.0876 BLAminus -132.14, -176.18 59.41, 61.38 -75.54, 13.79 297.0, 90.53 -57.03, -33.73 in-in in 8.4164 Saltbr-in 2.6742 HRD-in -71.8, -49.24 65.42, 10.92 in-in-in SNCiii in-in ActLoopNT-in 2.8622 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.74, 154.91 APE9-dihe-na 121.49, 170.06 APE8-dihe-in -75.28, 127.31 APE8-rot-in 302.17 APE67-dihe-in -70.63, -20.74 -49.24, -47.09 APE12-dist-in 9.075 APE11-dist-in 11.6816 APE10-dist-in 5.856 APE9-dist-in 3.2286 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 28 28 0 [[283, 534]] 1.0 AF-O75914-K1 Homo sapiens STE_PAK3_HUMAN STE 7.5e-95 323.0 1.0 257.0 257.0 419 420 421 423 425 312 328 332 399 401 400 402.0 459 447 442 441 440 439 438 437 436 358 Serine/threonine-protein kinase PAK 3
PAK3 PAK3_HUMAN AF-O75914-K3A O75914 275 542 559.0 No_ligand No_ligand Active DFGin 5.8036 14.8046 BLAminus -136.32, -175.1 65.13, 61.42 -79.15, 5.3 292.02, 82.41 -58.35, -32.4 in-in in 9.1624 Saltbr-in 2.9638 HRD-in -72.63, -49.65 69.85, 1.97 in-in-in SNCiii in-in ActLoopNT-in 2.8683 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.62, 140.94 APE9-dihe-na 121.04, 177.69 APE8-dihe-in -88.2, 128.79 APE8-rot-in 306.84 APE67-dihe-in -67.63, -21.94 -41.8, -52.86 APE12-dist-in 9.6702 APE11-dist-in 11.8251 APE10-dist-in 5.9411 APE9-dist-in 3.1334 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 28 28 0 [[283, 534]] 1.0 AF-O75914-K3 Homo sapiens STE_PAK3_HUMAN STE 7.5e-95 323.0 1.0 257.0 257.0 419 420 421 423 425 312 328 332 399 401 400 402.0 459 447 442 441 440 439 438 437 436 358 Serine/threonine-protein kinase PAK 3

STE_PAK3 (Serine/threonine-protein kinase PAK 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name