NEK_NEK6 (Serine/threonine-protein kinase Nek6)

Total number of chains: 2
Active chains: 2
Uniprot: NEK6_HUMAN
Kinase Domain Residues: 45 - 305
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9HC98-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK6 AF-Q9HC98-K1A Q9HC98 37 313 313.0 No_ligand No_ligand Active DFGin 5.6763 13.2607 BLAminus -131.82, -170.22 57.82, 63.1 -82.72, 16.09 298.64, 2.98 -59.23, -26.48 in-in in 9.312 Saltbr-in 2.7161 HRD-in -79.58, -45.34 66.63, 2.64 in-in-in SNCiii in-in ActLoopNT-in 2.8673 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.94, 153.91 APE9-dihe-na 115.3, -173.7 APE8-dihe-in -89.25, 126.24 APE8-rot-in 302.47 APE67-dihe-in -66.81, -8.69 -48.9, -43.85 APE12-dist-in 9.0267 APE11-dist-in 11.8705 APE10-dist-in 5.9225 APE9-dist-in 3.6329 None None None AF2 -1.0 1.0 1.0 A 277.0 277.0 0 28 28 0 [[45, 305]] 1.0 AF-Q9HC98-K1 NEK_NEK6_HUMAN NEK 3.7e-111 376.7 1.0 255.0 255.0 189 190 191 193 195 74 93 97 169 171 170 172.0 229 217 212 211 210 209 208 207 206 123 Serine/threonine-protein kinase Nek6
NEK6 AF-Q9HC98-K3A Q9HC98 37 313 313.0 No_ligand No_ligand Active DFGin 5.7301 12.5965 BLAminus -142.77, -168.86 55.01, 64.11 -80.23, 15.57 297.05, 179.54 -62.55, -24.81 in-in in 9.1758 Saltbr-in 2.7385 HRD-in -79.52, -42.98 65.34, 2.52 in-in-in SNCiii in-in ActLoopNT-in 2.895 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.38, 156.07 APE9-dihe-na 106.87, -172.23 APE8-dihe-in -93.4, 122.18 APE8-rot-in 303.38 APE67-dihe-in -60.05, -15.32 -49.25, -42.97 APE12-dist-in 9.2719 APE11-dist-in 12.0673 APE10-dist-in 6.1083 APE9-dist-in 3.5903 None None None AF2 -1.0 1.0 1.0 A 277.0 277.0 0 28 28 0 [[45, 305]] 1.0 AF-Q9HC98-K3 NEK_NEK6_HUMAN NEK 3.7e-111 376.7 1.0 255.0 255.0 189 190 191 193 195 74 93 97 169 171 170 172.0 229 217 212 211 210 209 208 207 206 123 Serine/threonine-protein kinase Nek6

NEK_NEK6 (Serine/threonine-protein kinase Nek6)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9HC98-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK6 NEK6_HUMAN AF-Q9HC98-K1A Q9HC98 37 313 313.0 No_ligand No_ligand Active DFGin 5.6763 13.2607 BLAminus -131.82, -170.22 57.82, 63.1 -82.72, 16.09 298.64, 2.98 -59.23, -26.48 in-in in 9.312 Saltbr-in 2.7161 HRD-in -79.58, -45.34 66.63, 2.64 in-in-in SNCiii in-in ActLoopNT-in 2.8673 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.94, 153.91 APE9-dihe-na 115.3, -173.7 APE8-dihe-in -89.25, 126.24 APE8-rot-in 302.47 APE67-dihe-in -66.81, -8.69 -48.9, -43.85 APE12-dist-in 9.0267 APE11-dist-in 11.8705 APE10-dist-in 5.9225 APE9-dist-in 3.6329 None None None AF2 -1.0 1.0 1.0 A 277.0 277.0 0 28 28 0 [[45, 305]] 1.0 AF-Q9HC98-K1 Homo sapiens NEK_NEK6_HUMAN NEK 3.7e-111 376.7 1.0 255.0 255.0 189 190 191 193 195 74 93 97 169 171 170 172.0 229 217 212 211 210 209 208 207 206 123 Serine/threonine-protein kinase Nek6
NEK6 NEK6_HUMAN AF-Q9HC98-K3A Q9HC98 37 313 313.0 No_ligand No_ligand Active DFGin 5.7301 12.5965 BLAminus -142.77, -168.86 55.01, 64.11 -80.23, 15.57 297.05, 179.54 -62.55, -24.81 in-in in 9.1758 Saltbr-in 2.7385 HRD-in -79.52, -42.98 65.34, 2.52 in-in-in SNCiii in-in ActLoopNT-in 2.895 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.38, 156.07 APE9-dihe-na 106.87, -172.23 APE8-dihe-in -93.4, 122.18 APE8-rot-in 303.38 APE67-dihe-in -60.05, -15.32 -49.25, -42.97 APE12-dist-in 9.2719 APE11-dist-in 12.0673 APE10-dist-in 6.1083 APE9-dist-in 3.5903 None None None AF2 -1.0 1.0 1.0 A 277.0 277.0 0 28 28 0 [[45, 305]] 1.0 AF-Q9HC98-K3 Homo sapiens NEK_NEK6_HUMAN NEK 3.7e-111 376.7 1.0 255.0 255.0 189 190 191 193 195 74 93 97 169 171 170 172.0 229 217 212 211 210 209 208 207 206 123 Serine/threonine-protein kinase Nek6

NEK_NEK6 (Serine/threonine-protein kinase Nek6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name