NEK_NEK4 (Serine/threonine-protein kinase Nek4)

Total number of chains: 2
Active chains: 2
Uniprot: NEK4_HUMAN
Kinase Domain Residues: 6 - 261
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P51957-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK4 AF-P51957-K1A P51957 1 269 841.0 No_ligand No_ligand Active DFGin 5.9506 12.6522 BLAminus -136.17, -168.66 54.74, 80.73 -95.02, 20.26 296.44, 175.76 -60.98, -23.0 in-in in 8.5818 Saltbr-in 2.6945 HRD-in -73.23, -45.43 63.69, 3.21 in-in-in SNCiii in-in ActLoopNT-in 2.8439 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.28, 160.73 APE9-dihe-na 121.34, 171.83 APE8-dihe-in -80.02, 125.58 APE8-rot-in 301.33 APE67-dihe-in -68.92, -15.47 -49.04, -40.44 APE12-dist-in 9.0913 APE11-dist-in 12.4423 APE10-dist-in 6.6246 APE9-dist-in 3.6193 None None None AF2 -1.0 1.0 1.0 A 269.0 269.0 0 28 28 0 [[6, 261]] 1.0 AF-P51957-K1 NEK_NEK4_HUMAN NEK 7.9e-114 385.4 1.0 256.0 256.0 148 149 150 152 154 35 53 57 128 130 129 131.0 188 176 171 170 169 168 167 166 165 84 Serine/threonine-protein kinase Nek4
NEK4 AF-P51957-K3A P51957 1 269 841.0 No_ligand No_ligand Active DFGin 6.1011 12.7447 BLAminus -142.58, -165.14 54.55, 69.27 -85.65, 15.86 296.16, 173.27 -60.6, -22.58 in-in in 8.2967 Saltbr-in 2.6824 HRD-in -74.61, -45.17 66.1, -17.97 in-in-in SNCiii in-in ActLoopNT-in 2.8269 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.33, 149.33 APE9-dihe-na 128.01, -177.27 APE8-dihe-in -92.63, 122.23 APE8-rot-in 299.29 APE67-dihe-in -61.56, -16.98 -49.75, -41.16 APE12-dist-in 9.2188 APE11-dist-in 12.3024 APE10-dist-in 6.5941 APE9-dist-in 3.5122 None None None AF2 -1.0 1.0 1.0 A 269.0 269.0 0 28 28 0 [[6, 261]] 1.0 AF-P51957-K3 NEK_NEK4_HUMAN NEK 7.9e-114 385.4 1.0 256.0 256.0 148 149 150 152 154 35 53 57 128 130 129 131.0 188 176 171 170 169 168 167 166 165 84 Serine/threonine-protein kinase Nek4

NEK_NEK4 (Serine/threonine-protein kinase Nek4)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P51957-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK4 NEK4_HUMAN AF-P51957-K1A P51957 1 269 841.0 No_ligand No_ligand Active DFGin 5.9506 12.6522 BLAminus -136.17, -168.66 54.74, 80.73 -95.02, 20.26 296.44, 175.76 -60.98, -23.0 in-in in 8.5818 Saltbr-in 2.6945 HRD-in -73.23, -45.43 63.69, 3.21 in-in-in SNCiii in-in ActLoopNT-in 2.8439 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.28, 160.73 APE9-dihe-na 121.34, 171.83 APE8-dihe-in -80.02, 125.58 APE8-rot-in 301.33 APE67-dihe-in -68.92, -15.47 -49.04, -40.44 APE12-dist-in 9.0913 APE11-dist-in 12.4423 APE10-dist-in 6.6246 APE9-dist-in 3.6193 None None None AF2 -1.0 1.0 1.0 A 269.0 269.0 0 28 28 0 [[6, 261]] 1.0 AF-P51957-K1 Homo sapiens NEK_NEK4_HUMAN NEK 7.9e-114 385.4 1.0 256.0 256.0 148 149 150 152 154 35 53 57 128 130 129 131.0 188 176 171 170 169 168 167 166 165 84 Serine/threonine-protein kinase Nek4
NEK4 NEK4_HUMAN AF-P51957-K3A P51957 1 269 841.0 No_ligand No_ligand Active DFGin 6.1011 12.7447 BLAminus -142.58, -165.14 54.55, 69.27 -85.65, 15.86 296.16, 173.27 -60.6, -22.58 in-in in 8.2967 Saltbr-in 2.6824 HRD-in -74.61, -45.17 66.1, -17.97 in-in-in SNCiii in-in ActLoopNT-in 2.8269 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.33, 149.33 APE9-dihe-na 128.01, -177.27 APE8-dihe-in -92.63, 122.23 APE8-rot-in 299.29 APE67-dihe-in -61.56, -16.98 -49.75, -41.16 APE12-dist-in 9.2188 APE11-dist-in 12.3024 APE10-dist-in 6.5941 APE9-dist-in 3.5122 None None None AF2 -1.0 1.0 1.0 A 269.0 269.0 0 28 28 0 [[6, 261]] 1.0 AF-P51957-K3 Homo sapiens NEK_NEK4_HUMAN NEK 7.9e-114 385.4 1.0 256.0 256.0 148 149 150 152 154 35 53 57 128 130 129 131.0 188 176 171 170 169 168 167 166 165 84 Serine/threonine-protein kinase Nek4

NEK_NEK4 (Serine/threonine-protein kinase Nek4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name