NEK_NEK3 (Serine/threonine-protein kinase Nek3)

Total number of chains: 2
Active chains: 2
Uniprot: NEK3_HUMAN
Kinase Domain Residues: 4 - 257
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P51956-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK3 AF-P51956-K1A P51956 1 265 506.0 No_ligand No_ligand Active DFGin 6.2946 14.4012 BLAminus -132.87, -171.38 54.82, 82.59 -93.49, 16.24 285.33, 70.99 -61.92, -27.31 in-in in 8.6881 Saltbr-in 2.7348 HRD-in -74.77, -42.88 63.15, 5.81 in-in-in SNCiii in-in ActLoopNT-in 2.8624 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.24, 158.3 APE9-dihe-na 113.67, 166.14 APE8-dihe-in -79.22, 122.82 APE8-rot-in 301.09 APE67-dihe-in -69.65, -9.89 -33.76, -49.87 APE12-dist-in 9.1614 APE11-dist-in 11.6025 APE10-dist-in 5.7775 APE9-dist-in 3.3765 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 28 28 0 [[4, 257]] 1.0 AF-P51956-K1 NEK_NEK3_HUMAN NEK 6.4e-113 382.4 1.0 255.0 255.0 144 145 146 148 150 33 50 54 124 126 125 127.0 184 172 167 166 165 164 163 162 161 80 Serine/threonine-protein kinase Nek3
NEK3 AF-P51956-K3A P51956 1 265 506.0 No_ligand No_ligand Active DFGin 6.0451 14.103 BLAminus -139.87, -171.44 56.73, 72.04 -84.68, 9.62 282.35, 78.86 -61.42, -30.97 in-in in 7.9682 Saltbr-in 2.7101 HRD-in -78.24, -44.39 66.6, -10.13 in-in-in SNCiii in-in ActLoopNT-in 2.8403 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.05, 141.17 APE9-dihe-na 135.98, 164.24 APE8-dihe-in -77.23, 120.88 APE8-rot-in 296.49 APE67-dihe-in -64.95, -16.02 -48.85, -38.95 APE12-dist-in 9.48 APE11-dist-in 11.7534 APE10-dist-in 5.8934 APE9-dist-in 3.2394 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 28 28 0 [[4, 257]] 1.0 AF-P51956-K3 NEK_NEK3_HUMAN NEK 6.4e-113 382.4 1.0 255.0 255.0 144 145 146 148 150 33 50 54 124 126 125 127.0 184 172 167 166 165 164 163 162 161 80 Serine/threonine-protein kinase Nek3

NEK_NEK3 (Serine/threonine-protein kinase Nek3)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P51956-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK3 NEK3_HUMAN AF-P51956-K1A P51956 1 265 506.0 No_ligand No_ligand Active DFGin 6.2946 14.4012 BLAminus -132.87, -171.38 54.82, 82.59 -93.49, 16.24 285.33, 70.99 -61.92, -27.31 in-in in 8.6881 Saltbr-in 2.7348 HRD-in -74.77, -42.88 63.15, 5.81 in-in-in SNCiii in-in ActLoopNT-in 2.8624 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.24, 158.3 APE9-dihe-na 113.67, 166.14 APE8-dihe-in -79.22, 122.82 APE8-rot-in 301.09 APE67-dihe-in -69.65, -9.89 -33.76, -49.87 APE12-dist-in 9.1614 APE11-dist-in 11.6025 APE10-dist-in 5.7775 APE9-dist-in 3.3765 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 28 28 0 [[4, 257]] 1.0 AF-P51956-K1 Homo sapiens NEK_NEK3_HUMAN NEK 6.4e-113 382.4 1.0 255.0 255.0 144 145 146 148 150 33 50 54 124 126 125 127.0 184 172 167 166 165 164 163 162 161 80 Serine/threonine-protein kinase Nek3
NEK3 NEK3_HUMAN AF-P51956-K3A P51956 1 265 506.0 No_ligand No_ligand Active DFGin 6.0451 14.103 BLAminus -139.87, -171.44 56.73, 72.04 -84.68, 9.62 282.35, 78.86 -61.42, -30.97 in-in in 7.9682 Saltbr-in 2.7101 HRD-in -78.24, -44.39 66.6, -10.13 in-in-in SNCiii in-in ActLoopNT-in 2.8403 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.05, 141.17 APE9-dihe-na 135.98, 164.24 APE8-dihe-in -77.23, 120.88 APE8-rot-in 296.49 APE67-dihe-in -64.95, -16.02 -48.85, -38.95 APE12-dist-in 9.48 APE11-dist-in 11.7534 APE10-dist-in 5.8934 APE9-dist-in 3.2394 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 28 28 0 [[4, 257]] 1.0 AF-P51956-K3 Homo sapiens NEK_NEK3_HUMAN NEK 6.4e-113 382.4 1.0 255.0 255.0 144 145 146 148 150 33 50 54 124 126 125 127.0 184 172 167 166 165 164 163 162 161 80 Serine/threonine-protein kinase Nek3

NEK_NEK3 (Serine/threonine-protein kinase Nek3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name