STE_MYO3A (Myosin-IIIa)

Total number of chains: 2
Active chains: 2
Uniprot: MYO3A_HUMAN
Kinase Domain Residues: 21 - 287
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q8NEV4-K1A

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Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MYO3A AF-Q8NEV4-K1A Q8NEV4 13 295 1616.0 No_ligand No_ligand Active DFGin 6.7384 13.6389 BLAminus -136.81, 175.56 56.55, 75.43 -86.2, 14.28 292.69, 86.55 -61.07, -27.46 in-in in 8.7076 Saltbr-in 2.8011 HRD-in -74.12, -44.94 64.76, 7.18 in-in-in SNCiii in-in ActLoopNT-in 2.8686 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.14, 160.14 APE9-dihe-na 110.46, 175.6 APE8-dihe-in -78.08, 124.58 APE8-rot-in 306.64 APE67-dihe-in -73.02, -22.36 -47.96, -39.29 APE12-dist-in 8.7648 APE11-dist-in 11.318 APE10-dist-in 5.4013 APE9-dist-in 3.4939 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 28 28 0 [[21, 287]] 1.0 AF-Q8NEV4-K1 STE_MYO3A_HUMAN STE 1e-95 325.8 1.0 257.0 257.0 167 168 169 171 173 50 65 69 147 149 148 150.0 212 195 190 189 188 187 186 185 184 101 Myosin-IIIa
MYO3A AF-Q8NEV4-K3A Q8NEV4 13 295 1616.0 No_ligand No_ligand Active DFGin 6.4995 13.4551 BLAminus -144.94, 173.26 62.19, 68.71 -83.34, 9.33 302.56, 102.83 -58.88, -23.4 in-in in 8.9266 Saltbr-in 2.8981 HRD-in -73.43, -45.08 66.73, 3.76 in-in-in SNCiii in-in ActLoopNT-in 2.8741 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.59, 142.15 APE9-dihe-na 144.94, 176.94 APE8-dihe-in -79.44, 125.51 APE8-rot-in 300.76 APE67-dihe-in -72.31, -25.43 -48.14, -41.94 APE12-dist-in 9.2409 APE11-dist-in 11.5194 APE10-dist-in 5.7373 APE9-dist-in 3.248 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 28 28 0 [[21, 287]] 1.0 AF-Q8NEV4-K3 STE_MYO3A_HUMAN STE 1e-95 325.8 1.0 257.0 257.0 167 168 169 171 173 50 65 69 147 149 148 150.0 212 195 190 189 188 187 186 185 184 101 Myosin-IIIa

STE_MYO3A (Myosin-IIIa)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q8NEV4-K1A

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MYO3A MYO3A_HUMAN AF-Q8NEV4-K1A Q8NEV4 13 295 1616.0 No_ligand No_ligand Active DFGin 6.7384 13.6389 BLAminus -136.81, 175.56 56.55, 75.43 -86.2, 14.28 292.69, 86.55 -61.07, -27.46 in-in in 8.7076 Saltbr-in 2.8011 HRD-in -74.12, -44.94 64.76, 7.18 in-in-in SNCiii in-in ActLoopNT-in 2.8686 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.14, 160.14 APE9-dihe-na 110.46, 175.6 APE8-dihe-in -78.08, 124.58 APE8-rot-in 306.64 APE67-dihe-in -73.02, -22.36 -47.96, -39.29 APE12-dist-in 8.7648 APE11-dist-in 11.318 APE10-dist-in 5.4013 APE9-dist-in 3.4939 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 28 28 0 [[21, 287]] 1.0 AF-Q8NEV4-K1 Homo sapiens STE_MYO3A_HUMAN STE 1e-95 325.8 1.0 257.0 257.0 167 168 169 171 173 50 65 69 147 149 148 150.0 212 195 190 189 188 187 186 185 184 101 Myosin-IIIa
MYO3A MYO3A_HUMAN AF-Q8NEV4-K3A Q8NEV4 13 295 1616.0 No_ligand No_ligand Active DFGin 6.4995 13.4551 BLAminus -144.94, 173.26 62.19, 68.71 -83.34, 9.33 302.56, 102.83 -58.88, -23.4 in-in in 8.9266 Saltbr-in 2.8981 HRD-in -73.43, -45.08 66.73, 3.76 in-in-in SNCiii in-in ActLoopNT-in 2.8741 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.59, 142.15 APE9-dihe-na 144.94, 176.94 APE8-dihe-in -79.44, 125.51 APE8-rot-in 300.76 APE67-dihe-in -72.31, -25.43 -48.14, -41.94 APE12-dist-in 9.2409 APE11-dist-in 11.5194 APE10-dist-in 5.7373 APE9-dist-in 3.248 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 28 28 0 [[21, 287]] 1.0 AF-Q8NEV4-K3 Homo sapiens STE_MYO3A_HUMAN STE 1e-95 325.8 1.0 257.0 257.0 167 168 169 171 173 50 65 69 147 149 148 150.0 212 195 190 189 188 187 186 185 184 101 Myosin-IIIa

STE_MYO3A (Myosin-IIIa)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name