CAMK_MYLK4 (Myosin light chain kinase family member 4)

Total number of chains: 4
Active chains: 2
Uniprot: MYLK4_HUMAN
Kinase Domain Residues: 104 - 361
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 2X4FB
DFGin BLAminus 2 50.0% AF-Q86YV6-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MYLK4 AF-Q86YV6-K1A Q86YV6 96 369 388.0 No_ligand No_ligand Active DFGin 6.1677 13.6713 BLAminus -123.76, 177.22 58.12, 74.61 -83.18, 16.73 298.72, 103.28 -59.31, -32.51 in-in in 9.1608 Saltbr-in 2.7779 HRD-in -78.56, -49.82 62.36, 13.93 in-in-in SNCiii in-in ActLoopNT-in 2.8633 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.01, 162.01 APE9-dihe-na 125.05, 175.6 APE8-dihe-in -85.72, 124.99 APE8-rot-in 309.59 APE67-dihe-in -56.95, -29.01 -46.3, -45.91 APE12-dist-in 8.3091 APE11-dist-in 11.8309 APE10-dist-in 6.852 APE9-dist-in 4.7718 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[104, 361]] 1.0 AF-Q86YV6-K1 CAMK_MYLK4_HUMAN CAMK 1.6e-86 295.7 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4
MYLK4 AF-Q86YV6-K3A Q86YV6 96 369 388.0 No_ligand No_ligand Active DFGin 5.8982 13.4847 BLAminus -127.05, -179.68 55.11, 75.49 -84.43, 16.06 303.59, 104.43 -58.98, -33.28 in-in in 9.1466 Saltbr-in 2.7484 HRD-in -81.51, -47.62 67.83, -1.34 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.47, 163.06 APE9-dihe-na 133.9, 176.55 APE8-dihe-in -81.28, 124.88 APE8-rot-in 305.78 APE67-dihe-in -60.11, -28.48 -47.26, -46.08 APE12-dist-in 7.7469 APE11-dist-in 11.4519 APE10-dist-in 7.3546 APE9-dist-in 4.9754 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[104, 361]] 1.0 AF-Q86YV6-K3 CAMK_MYLK4_HUMAN CAMK 1.6e-86 295.7 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4
MYLK4 2X4FA Q86YV6 80 373 388.0 16X:1374 Type1 Inactive DFGin 6.3509 13.7144 ABAminus -114.62, 5.88 -145.33, 138.81 -130.87, 35.13 298.6, 100.84 -58.07, -36.28 in-out in 9.72 Saltbr-out 5.5372 HRD-in -83.33, -58.18 76.53, 5.71 out-in-out SNCoio in-out ActLoopNT-in 2.8074 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -94.01, 6.99 APE9-dihe-na -65.55, 124.09 APE8-dihe-out 51.34, 71.53 APE8-rot-in 307.35 APE67-dihe-in -58.94, -19.09 -103.84, 16.38 APE12-dist-in 11.1929 APE11-dist-in 13.2664 APE10-dist-out 17.2295 APE9-dist-out 14.353 None None None XRAY 2.67 0.193 0.241 A 373.0 289.0 5 27 27 0 [[104, 361]] 1.0 2x4f CAMK_MYLK4_HUMAN CAMK 4.5e-86 294.5 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4
MYLK4 2X4FB Q86YV6 81 370 388.0 16X:1371 Type1 Inactive DFGin 6.3497 13.5797 ABAminus -116.67, 3.01 -141.83, 144.06 -136.88, 36.19 301.36, 99.86 -63.7, -27.74 in-out in 9.7448 Saltbr-out 5.2003 HRD-in -77.83, -57.08 77.66, -0.94 out-in-out SNCoio in-out ActLoopNT-in 2.7862 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -89.9, 9.25 APE9-dihe-na -67.43, 122.64 APE8-dihe-out 51.59, 67.64 APE8-rot-in 313.26 APE67-dihe-in -59.93, -20.27 -95.09, 16.01 APE12-dist-in 11.1371 APE11-dist-in 13.4698 APE10-dist-out 17.1302 APE9-dist-out 14.3044 None None None XRAY 2.67 0.193 0.241 B 373.0 288.0 2 27 27 0 [[104, 361]] 1.0 2x4f CAMK_MYLK4_HUMAN CAMK 4.5e-86 294.5 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4

CAMK_MYLK4 (Myosin light chain kinase family member 4)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 2X4FB
DFGin BLAminus 2 50.0% AF-Q86YV6-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MYLK4 MYLK4_HUMAN AF-Q86YV6-K1A Q86YV6 96 369 388.0 No_ligand No_ligand Active DFGin 6.1677 13.6713 BLAminus -123.76, 177.22 58.12, 74.61 -83.18, 16.73 298.72, 103.28 -59.31, -32.51 in-in in 9.1608 Saltbr-in 2.7779 HRD-in -78.56, -49.82 62.36, 13.93 in-in-in SNCiii in-in ActLoopNT-in 2.8633 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.01, 162.01 APE9-dihe-na 125.05, 175.6 APE8-dihe-in -85.72, 124.99 APE8-rot-in 309.59 APE67-dihe-in -56.95, -29.01 -46.3, -45.91 APE12-dist-in 8.3091 APE11-dist-in 11.8309 APE10-dist-in 6.852 APE9-dist-in 4.7718 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[104, 361]] 1.0 AF-Q86YV6-K1 Homo sapiens CAMK_MYLK4_HUMAN CAMK 1.6e-86 295.7 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4
MYLK4 MYLK4_HUMAN AF-Q86YV6-K3A Q86YV6 96 369 388.0 No_ligand No_ligand Active DFGin 5.8982 13.4847 BLAminus -127.05, -179.68 55.11, 75.49 -84.43, 16.06 303.59, 104.43 -58.98, -33.28 in-in in 9.1466 Saltbr-in 2.7484 HRD-in -81.51, -47.62 67.83, -1.34 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.47, 163.06 APE9-dihe-na 133.9, 176.55 APE8-dihe-in -81.28, 124.88 APE8-rot-in 305.78 APE67-dihe-in -60.11, -28.48 -47.26, -46.08 APE12-dist-in 7.7469 APE11-dist-in 11.4519 APE10-dist-in 7.3546 APE9-dist-in 4.9754 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[104, 361]] 1.0 AF-Q86YV6-K3 Homo sapiens CAMK_MYLK4_HUMAN CAMK 1.6e-86 295.7 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4
MYLK4 MYLK4_HUMAN 2X4FA Q86YV6 80 373 388.0 16X:1374 Type1 Inactive DFGin 6.3509 13.7144 ABAminus -114.62, 5.88 -145.33, 138.81 -130.87, 35.13 298.6, 100.84 -58.07, -36.28 in-out in 9.72 Saltbr-out 5.5372 HRD-in -83.33, -58.18 76.53, 5.71 out-in-out SNCoio in-out ActLoopNT-in 2.8074 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -94.01, 6.99 APE9-dihe-na -65.55, 124.09 APE8-dihe-out 51.34, 71.53 APE8-rot-in 307.35 APE67-dihe-in -58.94, -19.09 -103.84, 16.38 APE12-dist-in 11.1929 APE11-dist-in 13.2664 APE10-dist-out 17.2295 APE9-dist-out 14.353 None None None XRAY 2.67 0.193 0.241 A 373.0 289.0 5 27 27 0 [[104, 361]] 1.0 2x4f Homo sapiens CAMK_MYLK4_HUMAN CAMK 4.5e-86 294.5 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4
MYLK4 MYLK4_HUMAN 2X4FB Q86YV6 81 370 388.0 16X:1371 Type1 Inactive DFGin 6.3497 13.5797 ABAminus -116.67, 3.01 -141.83, 144.06 -136.88, 36.19 301.36, 99.86 -63.7, -27.74 in-out in 9.7448 Saltbr-out 5.2003 HRD-in -77.83, -57.08 77.66, -0.94 out-in-out SNCoio in-out ActLoopNT-in 2.7862 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -89.9, 9.25 APE9-dihe-na -67.43, 122.64 APE8-dihe-out 51.59, 67.64 APE8-rot-in 313.26 APE67-dihe-in -59.93, -20.27 -95.09, 16.01 APE12-dist-in 11.1371 APE11-dist-in 13.4698 APE10-dist-out 17.1302 APE9-dist-out 14.3044 None None None XRAY 2.67 0.193 0.241 B 373.0 288.0 2 27 27 0 [[104, 361]] 1.0 2x4f Homo sapiens CAMK_MYLK4_HUMAN CAMK 4.5e-86 294.5 5.0 256.0 252.0 246 247 248 250 252 135 151 155 224 226 225 227.0 285 273 268 267 266 265 264 263 262 181 Myosin light chain kinase family member 4

CAMK_MYLK4 (Myosin light chain kinase family member 4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name