TYR_MST1R (Macrophage-stimulating protein receptor)

Total number of chains: 4
Active chains: 2
Uniprot: RON_HUMAN
Kinase Domain Residues: 1080 - 1343
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q04912-K1A
DFGin BLBplus 2 50.0% 8ZKDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MST1R AF-Q04912-K1A Q04912 1072 1351 1400.0 No_ligand No_ligand Active DFGin 6.2818 14.4618 BLAminus -141.99, -179.45 59.52, 75.28 -86.8, 14.49 298.5, 109.69 -58.17, -33.61 in-in in 8.2175 Saltbr-in 2.6317 HRD-in -72.72, -43.94 66.74, -14.42 in-in-in SNCiii in-in ActLoopNT-in 3.0517 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.86, 108.34 APE9-dihe-in -93.05, 148.17 APE8-dihe-in -79.31, 66.76 APE8-rot-na 36.39 APE67-dihe-in -74.17, -12.48 -42.36, -41.66 APE12-dist-na 13.4073 APE11-dist-na 8.0283 APE10-dist-na 10.377 APE9-dist-in 6.6596 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 32 32 0 [[1082, 1343]] 1.0 AF-Q04912-K1 TYR_MST1R_HUMAN TYR 9.8e-89 303.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor
MST1R AF-Q04912-K3A Q04912 1072 1351 1400.0 No_ligand No_ligand Active DFGin 6.5306 13.9061 BLAminus -145.94, -177.24 58.06, 63.71 -79.93, 12.91 303.19, 113.83 -61.23, -33.51 in-in in 8.5499 Saltbr-in 2.719 HRD-in -73.56, -45.72 65.65, -12.22 in-in-in SNCiii in-in ActLoopNT-in 3.0889 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.52, 98.98 APE9-dihe-in -86.58, 144.76 APE8-dihe-in -81.58, 60.26 APE8-rot-na 37.35 APE67-dihe-in -73.35, -12.38 -43.26, -40.36 APE12-dist-na 13.3523 APE11-dist-na 8.2877 APE10-dist-na 9.9574 APE9-dist-in 6.6626 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 32 32 0 [[1082, 1343]] 1.0 AF-Q04912-K3 TYR_MST1R_HUMAN TYR 9.8e-89 303.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor
MST1R 3PLSA Q04912 1060 1357 1400.0 ANP:1358 ATPlike Inactive DFGin 6.2964 13.4362 BLBplus -158.57, 169.48 54.59, 28.32 -75.35, 163.89 46.83, 88.44 77.37, 8.52 out-out out 14.5017 Saltbr-out 15.6805 HRD-in -64.04, -56.3 78.09, -13.1 out-out-out SNCooo out-out ActLoopNT-out 7.3962 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -133.31, 27.58 APE9-dihe-in -79.04, 151.37 APE8-dihe-out -60.01, -26.4 APE8-rot-na 344.59 APE67-dihe-in -77.79, -6.02 -43.7, -39.07 APE12-dist-na 21.5297 APE11-dist-na 22.4916 APE10-dist-na 18.0334 APE9-dist-out 10.6231 M1254T None None XRAY 2.24 0.235 0.29 A 298.0 298.0 0 32 32 0 [[1082, 1343]] 1.0 3pls TYR_MST1R_HUMAN TYR 3.8e-88 301.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor
MST1R 8ZKDA Q04912 1060 1357 1400.0 ANP:1401 ATPlike Inactive DFGin 5.9634 13.4449 BLBplus -136.42, 163.89 75.82, 17.06 -71.65, 165.79 57.65, 82.07 74.72, 11.98 out-out out 14.7199 Saltbr-out 14.9554 HRD-in -65.95, -60.68 80.92, -14.74 out-out-out SNCooo out-out ActLoopNT-out 7.373 ActLoopCT-out TYR APEdihe_iooai APEdist_aaao APE10-dihe-in -84.37, 161.73 APE9-dihe-out -52.23, -44.7 APE8-dihe-out -56.31, -27.37 APE8-rot-na 334.62 APE67-dihe-in -83.51, -2.98 -41.89, -46.09 APE12-dist-na 22.0591 APE11-dist-na 19.0322 APE10-dist-na 14.2218 APE9-dist-out 10.029 None None None XRAY 2.05 0.18 0.231 A 298.0 298.0 0 32 32 0 [[1082, 1343]] 1.0 8zkd TYR_MST1R_HUMAN TYR 3.8e-88 301.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor

TYR_MST1R (Macrophage-stimulating protein receptor)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q04912-K1A
DFGin BLBplus 2 50.0% 8ZKDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MST1R RON_HUMAN AF-Q04912-K1A Q04912 1072 1351 1400.0 No_ligand No_ligand Active DFGin 6.2818 14.4618 BLAminus -141.99, -179.45 59.52, 75.28 -86.8, 14.49 298.5, 109.69 -58.17, -33.61 in-in in 8.2175 Saltbr-in 2.6317 HRD-in -72.72, -43.94 66.74, -14.42 in-in-in SNCiii in-in ActLoopNT-in 3.0517 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.86, 108.34 APE9-dihe-in -93.05, 148.17 APE8-dihe-in -79.31, 66.76 APE8-rot-na 36.39 APE67-dihe-in -74.17, -12.48 -42.36, -41.66 APE12-dist-na 13.4073 APE11-dist-na 8.0283 APE10-dist-na 10.377 APE9-dist-in 6.6596 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 32 32 0 [[1082, 1343]] 1.0 AF-Q04912-K1 Homo sapiens TYR_MST1R_HUMAN TYR 9.8e-89 303.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor
MST1R RON_HUMAN AF-Q04912-K3A Q04912 1072 1351 1400.0 No_ligand No_ligand Active DFGin 6.5306 13.9061 BLAminus -145.94, -177.24 58.06, 63.71 -79.93, 12.91 303.19, 113.83 -61.23, -33.51 in-in in 8.5499 Saltbr-in 2.719 HRD-in -73.56, -45.72 65.65, -12.22 in-in-in SNCiii in-in ActLoopNT-in 3.0889 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.52, 98.98 APE9-dihe-in -86.58, 144.76 APE8-dihe-in -81.58, 60.26 APE8-rot-na 37.35 APE67-dihe-in -73.35, -12.38 -43.26, -40.36 APE12-dist-na 13.3523 APE11-dist-na 8.2877 APE10-dist-na 9.9574 APE9-dist-in 6.6626 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 32 32 0 [[1082, 1343]] 1.0 AF-Q04912-K3 Homo sapiens TYR_MST1R_HUMAN TYR 9.8e-89 303.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor
MST1R RON_HUMAN 3PLSA Q04912 1060 1357 1400.0 ANP:1358 ATPlike Inactive DFGin 6.2964 13.4362 BLBplus -158.57, 169.48 54.59, 28.32 -75.35, 163.89 46.83, 88.44 77.37, 8.52 out-out out 14.5017 Saltbr-out 15.6805 HRD-in -64.04, -56.3 78.09, -13.1 out-out-out SNCooo out-out ActLoopNT-out 7.3962 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -133.31, 27.58 APE9-dihe-in -79.04, 151.37 APE8-dihe-out -60.01, -26.4 APE8-rot-na 344.59 APE67-dihe-in -77.79, -6.02 -43.7, -39.07 APE12-dist-na 21.5297 APE11-dist-na 22.4916 APE10-dist-na 18.0334 APE9-dist-out 10.6231 M1254T None None XRAY 2.24 0.235 0.29 A 298.0 298.0 0 32 32 0 [[1082, 1343]] 1.0 3pls Homo sapiens TYR_MST1R_HUMAN TYR 3.8e-88 301.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor
MST1R RON_HUMAN 8ZKDA Q04912 1060 1357 1400.0 ANP:1401 ATPlike Inactive DFGin 5.9634 13.4449 BLBplus -136.42, 163.89 75.82, 17.06 -71.65, 165.79 57.65, 82.07 74.72, 11.98 out-out out 14.7199 Saltbr-out 14.9554 HRD-in -65.95, -60.68 80.92, -14.74 out-out-out SNCooo out-out ActLoopNT-out 7.373 ActLoopCT-out TYR APEdihe_iooai APEdist_aaao APE10-dihe-in -84.37, 161.73 APE9-dihe-out -52.23, -44.7 APE8-dihe-out -56.31, -27.37 APE8-rot-na 334.62 APE67-dihe-in -83.51, -2.98 -41.89, -46.09 APE12-dist-na 22.0591 APE11-dist-na 19.0322 APE10-dist-na 14.2218 APE9-dist-out 10.029 None None None XRAY 2.05 0.18 0.231 A 298.0 298.0 0 32 32 0 [[1082, 1343]] 1.0 8zkd Homo sapiens TYR_MST1R_HUMAN TYR 3.8e-88 301.1 4.0 260.0 257.0 1225 1226 1227 1229 1231 1114 1131 1135 1205 1207 1206 1208.0 1269 1257 1252 1251 1250 1249 1248 1247 1246 1162 Macrophage-stimulating protein receptor

TYR_MST1R (Macrophage-stimulating protein receptor)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name