AGC_MAST2 (Microtubule-associated serine/threonine-protein kinase 2)

Total number of chains: 2
Active chains: 2
Uniprot: MAST2_HUMAN
Kinase Domain Residues: 512 - 785
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q6P0Q8-K1A

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Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAST2 AF-Q6P0Q8-K1A Q6P0Q8 504 793 1798.0 No_ligand No_ligand Active DFGin 6.4112 13.3596 BLAminus -134.48, 176.64 63.48, 68.04 -78.49, 16.62 307.28, 103.65 -60.72, -22.41 in-in in 8.6624 Saltbr-in 2.6405 HRD-in -71.43, -51.38 68.67, -7.82 in-in-in SNCiii in-in ActLoopNT-in 2.8816 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.91, 149.43 APE9-dihe-na 128.65, -177.44 APE8-dihe-in -86.63, 114.88 APE8-rot-in 306.21 APE67-dihe-in -65.83, -23.52 -47.09, -39.32 APE12-dist-in 12.1384 APE11-dist-in 12.5681 APE10-dist-in 6.9445 APE9-dist-in 4.2457 None None None AF2 -1.0 1.0 1.0 A 290.0 290.0 0 43 43 0 [[512, 785]] 1.0 AF-Q6P0Q8-K1 AGC_MAST2_HUMAN AGC 6.8e-98 332.8 1.0 260.0 260.0 652 653 654 656 658 541 560 564 632 634 633 635.0 707 695 690 689 688 687 686 685 684 590 Microtubule-associated serine/threonine-protein kinase 2
MAST2 AF-Q6P0Q8-K3A Q6P0Q8 504 793 1798.0 No_ligand No_ligand Active DFGin 6.1038 13.4739 BLAminus -140.2, -179.55 56.73, 79.38 -84.63, 19.96 302.1, 96.79 -64.67, -19.66 in-in in 8.4761 Saltbr-in 2.6032 HRD-in -72.34, -47.12 71.88, -13.41 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.18, 149.37 APE9-dihe-na 125.46, -175.09 APE8-dihe-in -86.05, 115.5 APE8-rot-in 308.38 APE67-dihe-in -64.49, -22.71 -48.28, -41.41 APE12-dist-in 11.856 APE11-dist-in 12.1839 APE10-dist-in 6.8232 APE9-dist-in 4.6434 None None None AF2 -1.0 1.0 1.0 A 290.0 290.0 0 43 43 0 [[512, 785]] 1.0 AF-Q6P0Q8-K3 AGC_MAST2_HUMAN AGC 6.8e-98 332.8 1.0 260.0 260.0 652 653 654 656 658 541 560 564 632 634 633 635.0 707 695 690 689 688 687 686 685 684 590 Microtubule-associated serine/threonine-protein kinase 2

AGC_MAST2 (Microtubule-associated serine/threonine-protein kinase 2)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q6P0Q8-K1A

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAST2 MAST2_HUMAN AF-Q6P0Q8-K1A Q6P0Q8 504 793 1798.0 No_ligand No_ligand Active DFGin 6.4112 13.3596 BLAminus -134.48, 176.64 63.48, 68.04 -78.49, 16.62 307.28, 103.65 -60.72, -22.41 in-in in 8.6624 Saltbr-in 2.6405 HRD-in -71.43, -51.38 68.67, -7.82 in-in-in SNCiii in-in ActLoopNT-in 2.8816 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.91, 149.43 APE9-dihe-na 128.65, -177.44 APE8-dihe-in -86.63, 114.88 APE8-rot-in 306.21 APE67-dihe-in -65.83, -23.52 -47.09, -39.32 APE12-dist-in 12.1384 APE11-dist-in 12.5681 APE10-dist-in 6.9445 APE9-dist-in 4.2457 None None None AF2 -1.0 1.0 1.0 A 290.0 290.0 0 43 43 0 [[512, 785]] 1.0 AF-Q6P0Q8-K1 Homo sapiens AGC_MAST2_HUMAN AGC 6.8e-98 332.8 1.0 260.0 260.0 652 653 654 656 658 541 560 564 632 634 633 635.0 707 695 690 689 688 687 686 685 684 590 Microtubule-associated serine/threonine-protein kinase 2
MAST2 MAST2_HUMAN AF-Q6P0Q8-K3A Q6P0Q8 504 793 1798.0 No_ligand No_ligand Active DFGin 6.1038 13.4739 BLAminus -140.2, -179.55 56.73, 79.38 -84.63, 19.96 302.1, 96.79 -64.67, -19.66 in-in in 8.4761 Saltbr-in 2.6032 HRD-in -72.34, -47.12 71.88, -13.41 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.18, 149.37 APE9-dihe-na 125.46, -175.09 APE8-dihe-in -86.05, 115.5 APE8-rot-in 308.38 APE67-dihe-in -64.49, -22.71 -48.28, -41.41 APE12-dist-in 11.856 APE11-dist-in 12.1839 APE10-dist-in 6.8232 APE9-dist-in 4.6434 None None None AF2 -1.0 1.0 1.0 A 290.0 290.0 0 43 43 0 [[512, 785]] 1.0 AF-Q6P0Q8-K3 Homo sapiens AGC_MAST2_HUMAN AGC 6.8e-98 332.8 1.0 260.0 260.0 652 653 654 656 658 541 560 564 632 634 633 635.0 707 695 690 689 688 687 686 685 684 590 Microtubule-associated serine/threonine-protein kinase 2

AGC_MAST2 (Microtubule-associated serine/threonine-protein kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name