CAMK_MARK1 (Serine/threonine-protein kinase MARK1)

Total number of chains: 12
Active chains: 2
Uniprot: MARK1_HUMAN
Kinase Domain Residues: 60 - 311
Spatial label Dihedral label Number of Chains Percent Representative
None None 8 66.7% 2HAKE
DFGin BLAminus 4 33.3% AF-Q9P0L2-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9P0L2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 319 0 None None Serine/threonine-protein kinase MARK1
AF-Q9P0L2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 319 0 None None Serine/threonine-protein kinase MARK1
6C9DA 2.499 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 53 - 795 0 None T215E,K761S,R764S Serine/threonine-protein kinase MARK1
6C9DB 2.499 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 53 - 795 0 None T215E,K761S,R764S Serine/threonine-protein kinase MARK1
2HAKA 2.6 Inactive None‑None in-out out-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 55 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKB 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 53 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKC 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 53 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKD 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKE 2.6 Inactive None‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKF 2.6 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKG 2.6 Inactive None‑None in-out out-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 55 - 371 0 None None Serine/threonine-protein kinase MARK1
2HAKH 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1

CAMK_MARK1 (Serine/threonine-protein kinase MARK1)

Total number of chains: 12
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
None None 8 66.7% 2HAKE
DFGin BLAminus 4 33.3% AF-Q9P0L2-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MARK1_HUMAN AF-Q9P0L2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 319 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN AF-Q9P0L2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 319 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 6C9DA 2.499 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 53 - 795 0 None T215E,K761S,R764S Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 6C9DB 2.499 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 53 - 795 0 None T215E,K761S,R764S Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKA 2.6 Inactive None‑None in-out out-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 55 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKB 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 53 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKC 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 53 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKD 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKE 2.6 Inactive None‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKF 2.6 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKG 2.6 Inactive None‑None in-out out-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 55 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens
MARK1_HUMAN 2HAKH 2.6 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 54 - 371 0 None None Serine/threonine-protein kinase MARK1 Homo sapiens

CAMK_MARK1 (Serine/threonine-protein kinase MARK1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism