MARK1 (Serine/threonine-protein kinase MARK1)

Group: CAMK
Uniprot: MARK1_HUMAN
Domain boundary: 60 - 311


Total number of chains: 11
Spatial Dihedral Chains Representative
DFGin BLAminus 3 AF-Q9P0L2-K1A
None None 8 2HAKE
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q9P0L2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 52 - 319 None None 0
6C9DA 2.499 Active DFGin BLAminus in-in in-in No_ligand No_ligand 53 - 795 T215E,K761S,R764S None 0
6C9DB 2.499 Active DFGin BLAminus in-in in-in No_ligand No_ligand 53 - 795 T215E,K761S,R764S None 0
2HAKA 2.6 Inactive None None in-out out-out No_ligand No_ligand 55 - 371 None None 8
2HAKB 2.6 Inactive None None out-out out-none No_ligand No_ligand 53 - 371 None None 18
2HAKC 2.6 Inactive None None out-out out-none No_ligand No_ligand 53 - 371 None None 9
2HAKD 2.6 Inactive None None out-out out-none No_ligand No_ligand 54 - 371 None None 9
2HAKE 2.6 Inactive None None out-out out-out No_ligand No_ligand 54 - 371 None None 0
2HAKF 2.6 Inactive None None out-out out-out No_ligand No_ligand 54 - 371 None None 0
2HAKG 2.6 Inactive None None in-out out-none No_ligand No_ligand 55 - 371 None None 10
2HAKH 2.6 Inactive None None out-out out-none No_ligand No_ligand 54 - 371 None None 17

MARK1 (Serine/threonine-protein kinase MARK1)

Group: CAMK
Total number of chains: 11
Spatial Dihedral Chains Representative
DFGin BLAminus 3 AF-Q9P0L2-K1A
None None 8 2HAKE
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens MARK1_HUMAN AF-Q9P0L2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 52 - 319 None None 0
Homo sapiens MARK1_HUMAN 6C9DA 2.499 Active DFGin BLAminus in-in in-in No_ligand No_ligand 53 - 795 T215E,K761S,R764S None 0
Homo sapiens MARK1_HUMAN 6C9DB 2.499 Active DFGin BLAminus in-in in-in No_ligand No_ligand 53 - 795 T215E,K761S,R764S None 0
Homo sapiens MARK1_HUMAN 2HAKA 2.6 Inactive None None in-out out-out No_ligand No_ligand 55 - 371 None None 8
Homo sapiens MARK1_HUMAN 2HAKB 2.6 Inactive None None out-out out-none No_ligand No_ligand 53 - 371 None None 18
Homo sapiens MARK1_HUMAN 2HAKC 2.6 Inactive None None out-out out-none No_ligand No_ligand 53 - 371 None None 9
Homo sapiens MARK1_HUMAN 2HAKD 2.6 Inactive None None out-out out-none No_ligand No_ligand 54 - 371 None None 9
Homo sapiens MARK1_HUMAN 2HAKE 2.6 Inactive None None out-out out-out No_ligand No_ligand 54 - 371 None None 0
Homo sapiens MARK1_HUMAN 2HAKF 2.6 Inactive None None out-out out-out No_ligand No_ligand 54 - 371 None None 0
Homo sapiens MARK1_HUMAN 2HAKG 2.6 Inactive None None in-out out-none No_ligand No_ligand 55 - 371 None None 10
Homo sapiens MARK1_HUMAN 2HAKH 2.6 Inactive None None out-out out-none No_ligand No_ligand 54 - 371 None None 17

MARK1 (Serine/threonine-protein kinase MARK1)

No non-human structures known.