STE_MAP4K5 (Mitogen-activated protein kinase kinase kinase kinase 5)

Total number of chains: 2
Active chains: 2
Uniprot: M4K5_HUMAN
Kinase Domain Residues: 20 - 277
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9Y4K4-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAP4K5 AF-Q9Y4K4-K1A Q9Y4K4 12 285 846.0 No_ligand No_ligand Active DFGin 5.8463 14.4015 BLAminus -133.94, 175.36 58.06, 73.41 -87.38, 15.51 291.73, 85.03 -58.29, -24.85 in-in in 8.6425 Saltbr-in 2.7343 HRD-in -84.18, -46.07 67.0, 6.09 in-in-in SNCiii in-in ActLoopNT-in 2.8082 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.17, 150.94 APE9-dihe-na 125.44, 173.43 APE8-dihe-in -79.04, 132.24 APE8-rot-in 306.88 APE67-dihe-inflip 74.9, -40.17 -49.79, 158.1 APE12-dist-in 8.6005 APE11-dist-in 11.8428 APE10-dist-in 6.0664 APE9-dist-in 3.5818 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[20, 277]] 1.0 AF-Q9Y4K4-K1 STE_MAP4K5_HUMAN STE 5.4e-97 330.1 1.0 257.0 257.0 157 158 159 161 163 49 65 69 137 139 138 140.0 200 185 180 179 178 177 176 175 174 95 Mitogen-activated protein kinase kinase kinase kinase 5
MAP4K5 AF-Q9Y4K4-K3A Q9Y4K4 12 285 846.0 No_ligand No_ligand Active DFGin 5.5949 14.2491 BLAminus -135.16, 176.01 54.68, 72.15 -81.36, 11.63 288.78, 83.39 -55.78, -31.5 in-in in 8.7627 Saltbr-in 2.7454 HRD-in -84.35, -44.08 67.31, 3.74 in-in-in SNCiii in-in ActLoopNT-in 2.9361 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.8, 148.0 APE9-dihe-na 130.72, 173.23 APE8-dihe-in -81.48, 125.83 APE8-rot-in 303.14 APE67-dihe-in -72.21, -23.3 -45.46, -48.9 APE12-dist-in 9.0254 APE11-dist-in 11.73 APE10-dist-in 6.0289 APE9-dist-in 3.2837 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[20, 277]] 1.0 AF-Q9Y4K4-K3 STE_MAP4K5_HUMAN STE 5.4e-97 330.1 1.0 257.0 257.0 157 158 159 161 163 49 65 69 137 139 138 140.0 200 185 180 179 178 177 176 175 174 95 Mitogen-activated protein kinase kinase kinase kinase 5

STE_MAP4K5 (Mitogen-activated protein kinase kinase kinase kinase 5)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9Y4K4-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAP4K5 M4K5_HUMAN AF-Q9Y4K4-K1A Q9Y4K4 12 285 846.0 No_ligand No_ligand Active DFGin 5.8463 14.4015 BLAminus -133.94, 175.36 58.06, 73.41 -87.38, 15.51 291.73, 85.03 -58.29, -24.85 in-in in 8.6425 Saltbr-in 2.7343 HRD-in -84.18, -46.07 67.0, 6.09 in-in-in SNCiii in-in ActLoopNT-in 2.8082 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.17, 150.94 APE9-dihe-na 125.44, 173.43 APE8-dihe-in -79.04, 132.24 APE8-rot-in 306.88 APE67-dihe-inflip 74.9, -40.17 -49.79, 158.1 APE12-dist-in 8.6005 APE11-dist-in 11.8428 APE10-dist-in 6.0664 APE9-dist-in 3.5818 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[20, 277]] 1.0 AF-Q9Y4K4-K1 Homo sapiens STE_MAP4K5_HUMAN STE 5.4e-97 330.1 1.0 257.0 257.0 157 158 159 161 163 49 65 69 137 139 138 140.0 200 185 180 179 178 177 176 175 174 95 Mitogen-activated protein kinase kinase kinase kinase 5
MAP4K5 M4K5_HUMAN AF-Q9Y4K4-K3A Q9Y4K4 12 285 846.0 No_ligand No_ligand Active DFGin 5.5949 14.2491 BLAminus -135.16, 176.01 54.68, 72.15 -81.36, 11.63 288.78, 83.39 -55.78, -31.5 in-in in 8.7627 Saltbr-in 2.7454 HRD-in -84.35, -44.08 67.31, 3.74 in-in-in SNCiii in-in ActLoopNT-in 2.9361 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.8, 148.0 APE9-dihe-na 130.72, 173.23 APE8-dihe-in -81.48, 125.83 APE8-rot-in 303.14 APE67-dihe-in -72.21, -23.3 -45.46, -48.9 APE12-dist-in 9.0254 APE11-dist-in 11.73 APE10-dist-in 6.0289 APE9-dist-in 3.2837 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 28 28 0 [[20, 277]] 1.0 AF-Q9Y4K4-K3 Homo sapiens STE_MAP4K5_HUMAN STE 5.4e-97 330.1 1.0 257.0 257.0 157 158 159 161 163 49 65 69 137 139 138 140.0 200 185 180 179 178 177 176 175 174 95 Mitogen-activated protein kinase kinase kinase kinase 5

STE_MAP4K5 (Mitogen-activated protein kinase kinase kinase kinase 5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name